APOBEC3A apolipoprotein B mRNA editing enzyme catalytic subunit 3A [Callithrix jacchus (white-tufted-ear marmoset)] - Gene

Summary

Gene symbol: APOBEC3A
Gene description: apolipoprotein B mRNA editing enzyme catalytic subunit 3A
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Callithrix jacchus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix
Orthologs: human all
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Genomic context

Location:: chromosome: 1

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2023_03	current	mCalJa1.2.pat.X (GCF_011100555.1)	1	NC_071442.1 (207097282..207102624)
105	previous assembly	Callithrix_jacchus_cj1700_1.1 (GCF_009663435.1)	1	NC_048383.1 (208132972..208138361)

Chromosome 1 - NC_071442.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables cytidine deaminase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA cytosine deamination	IEA Inferred from Electronic Annotation more info	PubMed
involved_in DNA demethylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cytidine to uridine editing	IEA Inferred from Electronic Annotation more info	PubMed
involved_in defense response to virus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in P-body	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: DNA dC->dU-editing enzyme APOBEC-3A

Names: apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A

NP_001288774.1

EC 3.5.4.38

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001301845.1 → NP_001288774.1 DNA dC->dU-editing enzyme APOBEC-3A

See identical proteins and their annotated locations for NP_001288774.1

Status: PROVISIONAL

Source sequence(s)

HQ404235

UniProtKB/TrEMBL

E9N3T9, F6R1Y1

Conserved Domains (3) summary

cd01283
Location:30 → 165

cytidine_deaminase; Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on ...

pfam05240
Location:136 → 181

APOBEC_C; APOBEC-like C-terminal domain

pfam08210
Location:18 → 193

APOBEC_N; APOBEC-like N-terminal domain