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APBA2 amyloid beta precursor protein binding family A member 2 [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100172037, updated on 3-Apr-2024

Summary

Gene symbol
APBA2
Gene description
amyloid beta precursor protein binding family A member 2
Locus tag
CR201_G0051382
See related
Ensembl:ENSPPYG00000006280
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs
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Genomic context

Location:
chromosome: 16
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 16 NC_072001.2 (32370166..32599203, complement)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 15 NC_072000.1 (29649828..29878865, complement)

Chromosome 16 - NC_072001.2Genomic Context describing neighboring genes Neighboring gene endosomal transmembrane epsin interactor 2 Neighboring gene DDB1- and CUL4-associated factor 6-like Neighboring gene uncharacterized LOC134760188 Neighboring gene golgin subfamily A member 6-like protein 1 Neighboring gene uncharacterized LOC129050033

Genomic regions, transcripts, and products

General gene information

Markers

Clone Names

  • DKFZp459H0530

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables amyloid-beta binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in dendritic spine IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
amyloid-beta A4 precursor protein-binding family A member 2
Names
Amyloid beta A4 precursor protein-binding family A member 2
amyloid beta (A4) precursor protein-binding, family A, member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001131678.1NP_001125150.1  amyloid-beta A4 precursor protein-binding family A member 2

    See identical proteins and their annotated locations for NP_001125150.1

    Status: PROVISIONAL

    Source sequence(s)
    CR858085
    UniProtKB/Swiss-Prot
    Q5RD33
    UniProtKB/TrEMBL
    A0A2J8RFG2
    Related
    ENSPPYP00000007120.2, ENSPPYT00000007415.2
    Conserved Domains (3) summary
    cd00992
    Location:657730
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd01208
    Location:363535
    PTB_X11; X11-like Phosphotyrosine-binding (PTB) domain
    pfam00595
    Location:568651
    PDZ; PDZ domain (Also known as DHR or GLGF)

RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_072001.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    32370166..32599203 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054531070.2XP_054387045.1  amyloid-beta A4 precursor protein-binding family A member 2 isoform X3

  2. XM_054531068.2XP_054387043.1  amyloid-beta A4 precursor protein-binding family A member 2 isoform X1

  3. XM_054531069.2XP_054387044.1  amyloid-beta A4 precursor protein-binding family A member 2 isoform X2

  4. XM_054531071.2XP_054387046.1  amyloid-beta A4 precursor protein-binding family A member 2 isoform X4

  5. XM_054531072.2XP_054387047.1  amyloid-beta A4 precursor protein-binding family A member 2 isoform X5