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ATP5F1A ATP synthase F1 subunit alpha [ Sus scrofa (pig) ]

Gene ID: 100157880, updated on 8-Mar-2024

Summary

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Official Symbol
ATP5F1Aprovided by VGNC
Official Full Name
ATP synthase F1 subunit alphaprovided by VGNC
Primary source
VGNC:VGNC:109475
See related
Ensembl:ENSSSCG00000004499
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
ATP5A1; ATP5A2
Expression
Ubiquitous expression in heart (RPKM 1037.9), psoas major muscle (RPKM 741.5) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
12
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 1 NC_010443.5 (95738789..95750835, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 1 NC_010443.4 (105944306..105955798)

Chromosome 1 - NC_010443.5Genomic Context describing neighboring genes Neighboring gene ectopic P-granules 5 autophagy tethering factor Neighboring gene proline-serine-threonine phosphatase interacting protein 2 Neighboring gene acyl-CoA-binding protein pseudogene Neighboring gene HAUS augmin like complex subunit 1 Neighboring gene arkadia (RNF111) N-terminal like PKA signaling regulator 2N

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Localization on the mitochondrial F1 ATPase alpha subunit of an epitope masked in the membrane-bound enzyme using a monoclonal antibody and synthetic peptides. Moradi-Améli M, et al. Eur J Biochem, 1991 Aug 1. PMID 1714390
  2. Evaluation and characterization of a porcine small intestine cDNA library: analysis of 839 clones. Wintero AK, et al. Mamm Genome, 1996 Jul. PMID 8672129
  3. Comparative analysis of protein coding sequences from human, mouse and the domesticated pig. Jørgensen FG, et al. BMC Biol, 2005 Jan 28. PMID 15679890, Free PMC Article
  4. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  5. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ADP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables proton-transporting ATP synthase activity, rotational mechanism IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proton motive force-driven ATP synthesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of mitochondrial proton-transporting ATP synthase, catalytic core IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of proton-transporting ATP synthase complex, catalytic core F(1) IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ATP synthase subunit alpha, mitochondrial
Names
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
cardiac muscle ATP synthase H+ transporting mitochondrial F1 complex alpha subunit 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001185142.1 → NP_001172071.1  ATP synthase subunit alpha, mitochondrial

    See identical proteins and their annotated locations for NP_001172071.1

    Status: PROVISIONAL

    Source sequence(s)
    EU650784
    UniProtKB/Swiss-Prot
    B2ZF46, P80021, Q29596
    UniProtKB/TrEMBL
    A0A4X1USY4, A0A8D0ZJG9
    Related
    ENSSSCP00000037224.1, ENSSSCT00000056853.2
    Conserved Domains (4) summary
    PRK09281
    Location:49 → 553
    PRK09281; F0F1 ATP synthase subunit alpha; Validated
    cd01132
    Location:137 → 418
    F1_ATPase_alpha; F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to ...
    pfam00306
    Location:427 → 521
    ATP-synt_ab_C; ATP synthase alpha/beta chain, C terminal domain
    pfam02874
    Location:69 → 135
    ATP-synt_ab_N; ATP synthase alpha/beta family, beta-barrel domain

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010443.5 Reference Sscrofa11.1 Primary Assembly

    Range
    95738789..95750835 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P80021.2 GenPept UniProtKB/Swiss-Prot:P80021

Gene LinkOut

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