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Adra2a adrenoceptor alpha 2A [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100135475, updated on 8-Mar-2024

Summary

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Gene symbol
Adra2a
Gene description
adrenoceptor alpha 2A
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947485.1 (84572167..84577073)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176408.1 (4463882..4465376, complement)

NW_026947485.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100717117 Neighboring gene uncharacterized LOC134475211 Neighboring gene SHOC2 leucine rich repeat scaffold protein Neighboring gene protein arginine N-methyltransferase 6-like Neighboring gene uncharacterized LOC134472726 Neighboring gene uncharacterized LOC134475212

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Heterologous expression of the cloned guinea pig alpha 2A, alpha 2B, and alpha 2C adrenoceptor subtypes. Radioligand binding and functional coupling to a CAMP-responsive reporter gene. Svensson SP, et al. Biochem Pharmacol, 1996 Feb 9. PMID 8573196

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables alpha2-adrenergic receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables epinephrine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating adrenergic receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in platelet activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of smooth muscle contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of vasoconstriction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alpha-2A adrenergic receptor
Names
adrenergic receptor, alpha 2a
adrenergic, alpha-2A-, receptor
alpha-2A adrenoceptor
alpha-2A adrenoreceptor
alpha-2AAR

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001172846.1 → NP_001166317.1  alpha-2A adrenergic receptor

    Status: PROVISIONAL

    Source sequence(s)
    U25722
    UniProtKB/Swiss-Prot
    Q60474
    Conserved Domains (1) summary
    cd15322
    Location:48 → 451
    7tmA_alpha2A_AR; alpha-2 adrenergic receptors subtype A, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947485.1 Reference mCavPor4.1

    Range
    84572167..84577073
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063233722.1 → XP_063089792.1  alpha-2A adrenergic receptor isoform X1

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q60474.2 GenPept UniProtKB/Swiss-Prot:Q60474

Gene LinkOut

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