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APOE apolipoprotein E [ Equus caballus (horse) ]

Gene ID: 100065481, updated on 8-Mar-2024

Summary

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Official Symbol
APOEprovided by VGNC
Official Full Name
apolipoprotein Eprovided by VGNC
Primary source
VGNC:VGNC:50996
See related
Ensembl:ENSECAG00000008236
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
4
Annotation release Status Assembly Chr Location
103 current EquCab3.0 (GCF_002863925.1) 10 NC_009153.3 (15712330..15715203)
102 previous assembly EquCab2.0 (GCF_000002305.2) 10 NC_009153.2 (15518582..15521077)

Chromosome 10 - NC_009153.3Genomic Context describing neighboring genes Neighboring gene mitochondrial import receptor subunit TOM40 homolog Neighboring gene translocase of outer mitochondrial membrane 40 Neighboring gene apolipoprotein C-I-like Neighboring gene uncharacterized LOC111775479 Neighboring gene apolipoprotein C1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables amyloid-beta binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables low-density lipoprotein particle receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables very-low-density lipoprotein particle receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cholesterol catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipoprotein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of neuron apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of nitric-oxide synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of amyloid-beta clearance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of intermediate-density lipoprotein particle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
apolipoprotein E

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009153.3 Reference EquCab3.0 Primary Assembly

    Range
    15712330..15715203
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005614763.3 → XP_005614820.3  apolipoprotein E

    UniProtKB/TrEMBL
    F6VBP9
    Conserved Domains (1) summary
    pfam01442
    Location:83 → 266
    Apolipoprotein; Apolipoprotein A1/A4/E domain

  2. XM_023649876.1 → XP_023505644.1  apolipoprotein E

    UniProtKB/TrEMBL
    F6VBP9
    Related
    ENSECAP00000006356.3, ENSECAT00000008481.3
    Conserved Domains (1) summary
    pfam01442
    Location:83 → 266
    Apolipoprotein; Apolipoprotein A1/A4/E domain
Nucleotide Protein
Heading Accession and Version

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