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ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif 17 [ Equus caballus (horse) ]

Gene ID: 100056538, updated on 8-Mar-2024

Summary

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Official Symbol
ADAMTS17provided by VGNC
Official Full Name
ADAM metallopeptidase with thrombospondin type 1 motif 17provided by VGNC
Primary source
VGNC:VGNC:15066
See related
Ensembl:ENSECAG00000000579
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See ADAMTS17 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
26
Annotation release Status Assembly Chr Location
103 current EquCab3.0 (GCF_002863925.1) 1 NC_009144.3 (106146049..106484463, complement)
102 previous assembly EquCab2.0 (GCF_000002305.2) 1 NC_009144.2 (105235329..105572646, complement)

Chromosome 1 - NC_009144.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111771401 Neighboring gene LysM domain containing 4 Neighboring gene ceramide synthase 3 Neighboring gene lines homolog 1 Neighboring gene ankyrin repeat and SOCS box containing 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
A disintegrin and metalloproteinase with thrombospondin motifs 17

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009144.3 Reference EquCab3.0 Primary Assembly

    Range
    106146049..106484463 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023651365.1 → XP_023507133.1  A disintegrin and metalloproteinase with thrombospondin motifs 17 isoform X4

    UniProtKB/TrEMBL
    A0A9L0SKN5, A0A9L0TKI3
    Related
    ENSECAP00000074560.1, ENSECAT00000112380.1
    Conserved Domains (6) summary
    smart00209
    Location:545 → 597
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:231 → 448
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam00090
    Location:894 → 947
    TSP_1; Thrombospondin type 1 domain
    pfam01562
    Location:81 → 180
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:699 → 809
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1081 → 1107
    PLAC; PLAC (protease and lacunin) domain

  2. XM_023651360.1 → XP_023507128.1  A disintegrin and metalloproteinase with thrombospondin motifs 17 isoform X2

    UniProtKB/TrEMBL
    A0A9L0TKI3, F7D7K7
    Related
    ENSECAP00000000622.4, ENSECAT00000000777.4
    Conserved Domains (6) summary
    smart00209
    Location:545 → 597
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:231 → 448
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam00090
    Location:917 → 970
    TSP_1; Thrombospondin type 1 domain
    pfam01562
    Location:81 → 180
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:699 → 832
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1104 → 1130
    PLAC; PLAC (protease and lacunin) domain

  3. XM_023651364.1 → XP_023507132.1  A disintegrin and metalloproteinase with thrombospondin motifs 17 isoform X3

    UniProtKB/TrEMBL
    A0A9L0TKI3
    Conserved Domains (6) summary
    smart00209
    Location:546 → 598
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:231 → 448
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam00090
    Location:895 → 948
    TSP_1; Thrombospondin type 1 domain
    pfam01562
    Location:81 → 180
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:700 → 810
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1082 → 1108
    PLAC; PLAC (protease and lacunin) domain

  4. XM_023651354.1 → XP_023507122.1  A disintegrin and metalloproteinase with thrombospondin motifs 17 isoform X1

    UniProtKB/TrEMBL
    A0A9L0TKI3
    Conserved Domains (6) summary
    smart00209
    Location:546 → 598
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:231 → 448
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam00090
    Location:918 → 971
    TSP_1; Thrombospondin type 1 domain
    pfam01562
    Location:81 → 180
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:700 → 833
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1105 → 1131
    PLAC; PLAC (protease and lacunin) domain

  5. XM_023651372.1 → XP_023507140.1  A disintegrin and metalloproteinase with thrombospondin motifs 17 isoform X5

    UniProtKB/TrEMBL
    A0A9L0SA14
    Conserved Domains (5) summary
    smart00209
    Location:546 → 598
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:231 → 448
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam00090
    Location:918 → 971
    TSP_1; Thrombospondin type 1 domain
    pfam01562
    Location:81 → 180
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:700 → 833
    ADAM_spacer1; ADAM-TS Spacer 1

  6. XM_023651382.1 → XP_023507150.1  A disintegrin and metalloproteinase with thrombospondin motifs 17 isoform X6

    UniProtKB/TrEMBL
    F7DNJ9
    Conserved Domains (4) summary
    smart00209
    Location:546 → 598
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:231 → 448
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam01562
    Location:81 → 180
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:700 → 833
    ADAM_spacer1; ADAM-TS Spacer 1
Nucleotide Protein
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