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pkmyt1 protein kinase, membrane associated tyrosine/threonine 1 [ Danio rerio (zebrafish) ]

Gene ID: 100049158, updated on 27-Mar-2024

Summary

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Official Symbol
pkmyt1provided by ZNC
Official Full Name
protein kinase, membrane associated tyrosine/threonine 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-060810-80
See related
Ensembl:ENSDARG00000074730 AllianceGenome:ZFIN:ZDB-GENE-060810-80
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:7157379; zgc:163016
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in meiotic cell cycle. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in nucleus. Orthologous to human PKMYT1 (protein kinase, membrane associated tyrosine/threonine 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (14965587..15002595, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (14927284..14964697, complement)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103911903 Neighboring gene neuronal differentiation 2 Neighboring gene myosin light chain, phosphorylatable, fast skeletal muscle b Neighboring gene phenylethanolamine N-methyltransferase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in meiotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of G2/MI transition of meiotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
NP_001091666.1
XP_005156179.1
XP_021335680.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098196.1 → NP_001091666.1  membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

    See identical proteins and their annotated locations for NP_001091666.1

    Status: PROVISIONAL

    Source sequence(s)
    BC139690
    UniProtKB/TrEMBL
    A4VCH1
    Related
    ENSDARP00000100899.1, ENSDART00000108852.4
    Conserved Domains (2) summary
    smart00220
    Location:108 → 371
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14050
    Location:106 → 369
    PKc_Myt1; Catalytic domain of the Dual-specificity protein kinase, Myt1

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    14965587..15002595 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005156122.4 → XP_005156179.1  membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform X1

    See identical proteins and their annotated locations for XP_005156179.1

    UniProtKB/TrEMBL
    A0A8M2B244, B1H1M4
    Related
    ENSDARP00000122987.1, ENSDART00000141909.2
    Conserved Domains (2) summary
    smart00220
    Location:108 → 371
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14050
    Location:106 → 369
    PKc_Myt1; Catalytic domain of the Dual-specificity protein kinase, Myt1

  2. XM_021480005.1 → XP_021335680.1  membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform X2

    UniProtKB/TrEMBL
    A0A8M9QMB9
    Conserved Domains (1) summary
    cl21453
    Location:106 → 338
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein Strain
Heading Accession and Version

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