AFP alpha fetoprotein [Equus caballus (horse)] - Gene

Summary

Official Symbol: AFPprovided by VGNC
Official Full Name: alpha fetoproteinprovided by VGNC
Primary source: VGNC:VGNC:51133
See related: Ensembl:ENSECAG00000023229
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Equus caballus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
103	current	EquCab3.0 (GCF_002863925.1)	3	NC_009146.3 (63964135..63985168, complement)
102	previous assembly	EquCab2.0 (GCF_000002305.2)	3	NC_009146.2 (62182429..62203462, complement)

Chromosome 3 - NC_009146.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

High-Risk Pregnancy Is Associated With Increased Alpha-Fetoprotein Concentrations in the Amniotic Fluid and Foal Plasma.
Title: High-Risk Pregnancy Is Associated With Increased Alpha-Fetoprotein Concentrations in the Amniotic Fluid and Foal Plasma.
Equine alpha-fetoprotein seems to be an important indicator of fetal well-being in horses.
Title: Equine alpha-fetoprotein levels in Lipizzaner mares with normal pregnancies and with pregnancy loss.
This study confirmed that alpha-fetoprotein (AFP) is present in the fetal fluids of mares during the third trimester of pregnancy; experimentally induced placentitis was associated with an elevation in maternal plasma concentrations of AFP.
Title: Alpha-fetoprotein is present in the fetal fluids and is increased in plasma of mares with experimentally induced ascending placentitis.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables fatty acid binding	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in transport	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in blood microparticle	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: alpha-fetoprotein

Names: alpha-1-fetoprotein; alpha-fetoglobulin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.