ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 [Equus caballus (horse)] - Gene

Summary

Official Symbol: ATP1A1provided by VGNC
Official Full Name: ATPase Na+/K+ transporting subunit alpha 1provided by VGNC
Primary source: VGNC:VGNC:49506
See related: Ensembl:ENSECAG00000024623
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Equus caballus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 5

Exon count:: 25

Annotation release	Status	Assembly	Chr	Location
103	current	EquCab3.0 (GCF_002863925.1)	5	NC_009148.3 (49182085..49212027, complement)
102	previous assembly	EquCab2.0 (GCF_000002305.2)	5	NC_009148.2 (52605199..52627488, complement)

Chromosome 5 - NC_009148.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info	PubMed
enables P-type sodium:potassium-exchanging transporter activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in intracellular potassium ion homeostasis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in intracellular sodium ion homeostasis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in potassium ion import across plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
involved_in proton transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in sodium ion export across plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: sodium/potassium-transporting ATPase subunit alpha-1

Names: ATPase, Na+/K+ transporting, alpha 1 polypeptide; Na(+)/K(+) ATPase alpha-1 subunit; alpha1 subunit of equine Na/K ATPase; horse alpha-1 subunit of Na,K-ATPase; sodium pump subunit alpha-1

NP_001108004.2

EC 7.2.2.13

XP_023495991.1

EC 7.2.2.13

XP_023495992.1

EC 7.2.2.13

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001114532.2 → NP_001108004.2 sodium/potassium-transporting ATPase subunit alpha-1

Status: PROVISIONAL

Source sequence(s)

PJAA01000006

UniProtKB/TrEMBL

A0A3Q2H1X8

Conserved Domains (6) summary

smart00831
Location:38 → 112

Cation_ATPase_N; Cation transporter/ATPase, N-terminus

COG4087
Location:604 → 750

COG4087; Soluble P-type ATPase [General function prediction only]

TIGR01106
Location:25 → 1021

ATPase-IIC_X-K; sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit

pfam00122
Location:132 → 363

E1-E2_ATPase; E1-E2 ATPase

pfam00689
Location:797 → 1006

Cation_ATPase_C; Cation transporting ATPase, C-terminus

pfam13246
Location:425 → 519

Cation_ATPase; Cation transport ATPase (P-type)

RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

NC_009148.3 Reference EquCab3.0 Primary Assembly

Range

49182085..49212027 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_023640223.1 → XP_023495991.1 sodium/potassium-transporting ATPase subunit alpha-1 isoform X1

UniProtKB/Swiss-Prot

P18907

UniProtKB/TrEMBL

A0A3Q2H1X8

Related

ENSECAP00000022397.3, ENSECAT00000026804.4

Conserved Domains (1) summary

TIGR01106
Location:25 → 1021

ATPase-IIC_X-K; sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit
XM_023640224.1 → XP_023495992.1 sodium/potassium-transporting ATPase subunit alpha-1 isoform X2

UniProtKB/TrEMBL

A0A3Q2H1X8

Related

ENSECAP00000027485.3, ENSECAT00000038896.3

Conserved Domains (1) summary

TIGR01106
Location:25 → 1021

ATPase-IIC_X-K; sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit