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arfip1 ADP-ribosylation factor interacting protein 1 (arfaptin 1) [ Danio rerio (zebrafish) ]

Gene ID: 100003895, updated on 27-Mar-2024

Summary

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Official Symbol
arfip1provided by ZNC
Official Full Name
ADP-ribosylation factor interacting protein 1 (arfaptin 1)provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2690
See related
Ensembl:ENSDARG00000070055 AllianceGenome:ZFIN:ZDB-GENE-040426-2690
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:66341; id:ibd2077; wu:fd18g10
Summary
Predicted to enable phospholipid binding activity. Predicted to be involved in intracellular protein transport and regulation of Arp2/3 complex-mediated actin nucleation. Predicted to act upstream of or within regulation of protein secretion. Predicted to be located in Golgi membrane. Predicted to be active in trans-Golgi network membrane. Is expressed in notochord. Orthologous to human ARFIP1 (ADP ribosylation factor interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (25441051..25486535, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (24750222..24795706, complement)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 2a Neighboring gene FH2 domain containing 1 Neighboring gene secreted frizzled-related protein 2 Neighboring gene uncharacterized LOC101882989

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Molecular evolution of melatonin receptor genes (mtnr) in vertebrates and its shedding light on mtnr1c. Li Y, et al. Gene, 2021 Feb 15. PMID 33164759
  2. Gene expression profiling of zebrafish embryonic retinal pigment epithelium in vivo. Leung YF, et al. Invest Ophthalmol Vis Sci, 2007 Feb. PMID 17251491, Free PMC Article
  3. A gene expression screen in zebrafish embryogenesis. Kudoh T, et al. Genome Res, 2001 Dec. PMID 11731487
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC66341, MGC174820

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein domain specific binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of Arp2/3 complex-mediated actin nucleation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in trans-Golgi network membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
arfaptin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213368.1 → NP_998533.1  arfaptin-1

    See identical proteins and their annotated locations for NP_998533.1

    Status: PROVISIONAL

    Source sequence(s)
    BC054687
    UniProtKB/TrEMBL
    A0A2R8QMC7, F6PB95, Q7SYK6
    Related
    ENSDARP00000093278.3, ENSDART00000102501.5
    Conserved Domains (1) summary
    cd07660
    Location:121 → 321
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    25441051..25486535 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005170893.3 → XP_005170950.1  arfaptin-1 isoform X3

    UniProtKB/TrEMBL
    A0A8M2BI85
    Conserved Domains (1) summary
    cd07660
    Location:155 → 355
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin

  2. XM_005170891.4 → XP_005170948.1  arfaptin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BI30
    Conserved Domains (1) summary
    cd07660
    Location:262 → 462
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin

  3. XM_005170892.4 → XP_005170949.1  arfaptin-1 isoform X2

    UniProtKB/TrEMBL
    A0A8M2BI53, F1Q8M3
    Related
    ENSDARP00000121937.1, ENSDART00000141892.3
    Conserved Domains (1) summary
    cd07660
    Location:228 → 428
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394484.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    74047..114474 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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