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apcdd1l adenomatosis polyposis coli down-regulated 1-like [ Danio rerio (zebrafish) ]

Gene ID: 100001408, updated on 27-Mar-2024

Summary

Official Symbol
apcdd1lprovided by ZNC
Official Full Name
adenomatosis polyposis coli down-regulated 1-likeprovided by ZNC
Primary source
ZFIN:ZDB-GENE-121022-3
See related
Ensembl:ENSDARG00000075557 AllianceGenome:ZFIN:ZDB-GENE-121022-3
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable Wnt-protein binding activity. Acts upstream of or within glial cell development and retina development in camera-type eye. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in atrium; brain; eye; post-vent region; and trunk. Human ortholog(s) of this gene implicated in hypotrichosis 1. Orthologous to several human genes including APCDD1L (APC down-regulated 1 like). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 6
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (49651794..49673447, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (49653231..49674792, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene RAB22A, member RAS oncogene family Neighboring gene VAMP (vesicle-associated membrane protein)-associated protein B and C Neighboring gene syntaxin 16 Neighboring gene aminopeptidase like 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    49651794..49673447 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001341376.5XP_001341412.1  protein APCDD1-like

    UniProtKB/TrEMBL
    A0A8M1PUY8, E7F3Y0
    Related
    ENSDARP00000102504.2, ENSDART00000112226.4
    Conserved Domains (1) summary
    pfam14921
    Location:52277
    APCDDC; Adenomatosis polyposis coli down-regulated 1

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394670.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    106503..131061 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021471845.1XP_021327520.1  protein APCDD1-like

    UniProtKB/TrEMBL
    A0A8M9Q271
    Conserved Domains (1) summary
    pfam14921
    Location:52277
    APCDDC; Adenomatosis polyposis coli down-regulated 1