RNA-seq Analysis of Wild Type and Ptpn11-deficient cerebellar Transcriptomes - - GEO DataSets

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RNA-seq Analysis of Wild Type and Ptpn11-deficient cerebellar Transcriptomes

(Submitter supplied) We have recently discovered that deletion of Ptpn11, which codes for protein tyrosine phosphatase Shp2, blocks Bergmann glia (BG) formation and cerebellar foliation, whereas expressing a constitutively active Mek1 (Map2k1), Mek1DD, reverses the Ptpn11-deficient phenotypes, uncovering a previously unappreciated role of BG in folding of the cerebellar cortex. Relatively little is known regarding to the BG induction. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL13112 GPL19057
28 Samples

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Accession:: GSE87104

ID:: 200087104

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