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Full record GDS4498

Transcription factor Nrf2 gain-of-function model: postnatal day 2.5 whole skin

Analysis of whole skin from female, K5cre-caNrf2 transgenics at P2.5. Nrf2 activation induced epidermal thickening and hyperkeratosis resembling human skin disease lamellar ichthyosis. Results provide insight into the role of Nrf2 as a regulator of protective functions of the epidermis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE35160
6 Samples
Download data: CEL

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