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Full record GDS3779

Chromogranin A-null model of hypertension: adrenal gland

Analysis of adrenal glands from 12-week old, chromogranin A knockouts (Chga KO). The Chga KO displays severe hypertension coupled with reduction in size, number, and density of regulated secretory granules. Results provide insight into the molecular basis of this monogenic hypertension model.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL81
Series:
GSE18332
6 Samples
Download data: CEL, CHP

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