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Full record GDS2169

Nuclear and extranuclear mutant huntingtin exon 1 protein effect on cerebellum

Analysis of cerebella of transgenics expressing mutant huntingtin (htt) exon 1 protein in nucleus only or in both nucleus and cytoplasm. The polyglutamine (polyQ) expansion in htt results in Huntington's disease (HD). Results provide insight into the impact of subcellular location of polyQ in HD.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 6 age, 3 agent, 5 strain sets
Platform:
GPL81
Series:
GSE3248
48 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS2169
ID:
2169

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