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Full record GDS4624

Unfolded Protein Response factor CHOP deficiency effect on Charcot-Marie-Tooth 1B sciatic nerves: developmental time course

Analysis of sciatic nerves from S63del/Chop-null animals from ages 5 days to 4 months. Deletion of serine 63 (P0S63del) causes demyelinating neuropathy similar to Charcot-Marie-Tooth 1B disease in humans. Results provide insight into molecular basis of myelination rescue in S63del/Chop-null nerves.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 age, 4 genotype/variation sets
Platform:
GPL8321
Series:
GSE40610
24 Samples
Download data: CEL
DataSet
Accession:
GDS4624
ID:
4624

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