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Full record GDS4986

Tumor-infiltrating CD8 T cells silenced for negative regulators of T cells

Analysis of CD8 T cells that were transduced with shRNAs targeting inhibitors of T-cell function, adoptively transferred into B16 tumor-bearing mice, and purified from spleen or tumor 7 days later. Results provide insight into molecular mechanisms blocking cytotoxic T cell infiltration into tumors.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 6 protocol, 2 tissue sets
Platform:
GPL1261
Series:
GSE53388
36 Samples
Download data: CEL

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