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Full record GDS4756

Bone marrow microenvironment effect on imatinib-treated chronic myeloid leukemia CD34+ cells

Analysis of CML cells treated with tyrosine kinase inhibitor (TKI) imatinib and BM mesenchymal stromal cells (MSCs). Coculture with MSCs protects the CML cells from TKI-mediated cell death and depletion. Results provide insight into microenvironmental protection of CML cells from TKI treatment.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 4 protocol, 2 tissue sets
Platform:
GPL6244
Series:
GSE43225
12 Samples
Download data: CEL

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