GEO DataSets

Developmental gene expression profiling of fetal orofacial tissue from gestation day (GD) 12-14 embryos.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 3 development stage sets

Platform:

GPL81

Series:

GSE1624

9 Samples

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(Submitter supplied) Developmental gene expression profiling of mammalian, fetal orofacial tissue Keywords = orofacial Keywords = embryo Keywords = development Keywords: time-course

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS739

Platform:

GPL81

9 Samples

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(Submitter supplied) BACKGROUND: Orofacial development is a multifaceted process involving precise, spatio-temporal expression of a panoply of genes. MicroRNAs (miRNAs) constitute the largest family of noncoding RNAs involved in gene silencing, and represent critical regulators of cell and tissue differentiation. MicroRNA gene expression profiling is an effective means of acquiring novel and valuable information regarding the expression and regulation of genes, under the control of miRNA, involved in mammalian orofacial development. more...

Organism:

Homo sapiens; Mus musculus; Rattus norvegicus

Type:

Non-coding RNA profiling by array

Platform:

GPL10179

9 Samples

Download data: TXT

(Submitter supplied) The overall goal of this project is to investigate the role of TGF-beta signaling in tongue development in order to study the contribution of cranial neural crest (CNC) cells towards the patterning of cranial mesoderm for proper tongue formation. Here, we conducted gene expression profiling of embryonic tongue tissue from wild type mice as well as those with a neural crest specific conditional inactivation of the Tgfbr2 gene. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

6 Samples

Download data: CEL

(Submitter supplied) BACKGROUND: Development of the neural tube is a highly orchestrated process relying on precise, spatio-temporal expression of numerous genes as well as hierarchies of signal transduction and gene regulatory networks. Disruption of expression of a number of genes participating in these networks is believed to underlie developmental anomalies such as neural tube defects (NTDs) resulting from anomalous neural tube morphogenesis. more...

Organism:

Mus musculus; Rattus norvegicus; Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL10178

9 Samples

Download data: TXT

(Submitter supplied) BACKGROUND: When resources are scant, C. elegans larvae arrest as long-lived dauers under the control of insulin/IGF- and TGFbeta-related signaling pathways. : We have identified genes that show different levels of expression in a comparison of wild-type L2 or L3 larvae (non-dauer) to TGFbeta mutants at similar developmental stages undergoing dauer formation. Many insulin/IGF pathway and other known dauer regulatory genes have changes in expression that suggest strong positive feedback by the TGFbeta pathway. more...

Organism:

Caenorhabditis elegans

Type:

Expression profiling by array

4 related Platforms

10 Samples

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(Submitter supplied) Mouse embryonic fibroblasts stimulated with varying doses of FGF2 in conventional hES cell medium were analysed on whole-genome expression chips to reveal altered expression of genes encoding secreted proteins. Keywords: Growth factor stimulation experiment

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS2421

Platform:

GPL4055

4 Samples

Download data: TXT

(Submitter supplied) Mouse embryonic fibroblasts stimulated with 40 ng/ml of FGF2 in conventional hES cell medium were analysed on whole-genome expression chips to reveal altered expression of genes encoding secreted proteins. Keywords: Growth factor stimulation experiment

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL4865

2 Samples

Download data: TXT

(Submitter supplied) Mouse embryonic fibroblasts stimulated with 40 ng/ml of FGF2 in conventional hES cell medium were analysed on whole-genome expression chips to reveal altered expression of genes encoding secreted proteins. Keywords: Growth factor stimulation experiment

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL4865

2 Samples

Download data: TXT

(Submitter supplied) Hybridisations were carried out to define a fibroblast-like cell type derived from H9 human embryonic stem cells. Keywords: cell type comparison

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS2423

Platform:

GPL2700

4 Samples

Download data: TXT

(Submitter supplied) This series includes hES cell samples starved and re-stimulated with FGF2. Controls were FGF2-starved but not re-stimulated. Two independent experiments were carried out (one sample plus control each). Keywords: Growth factor stimulation experiment

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS2422

Platform:

GPL2700

4 Samples

Download data: TXT

Analysis of embryonic fibroblast-like (EF) differentiated cells derived from H9 embryonic stem cells. Foreskin fibroblasts, and undifferentiated H9 and embryonic carcinoma cells also examined. Results provide insight into the differences between EF cells and fibroblasts at the molecular level.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 4 cell type sets

Platform:

GPL2700

Series:

GSE5416

4 Samples

Download data: TXT

Analysis of embryonic fibroblasts starved of fibroblast growth factor 2 (FGF2) for 2 days and subsequently restimulated with FGF2. FGF2 promotes the self-renewal of embryonic stem cells (ESCs) . Results provide insight into the molecular mechanisms underlying ESC self-renewal in response to FGF2.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 agent, 2 protocol sets

Platform:

GPL2700

Series:

GSE5415

4 Samples

Download data: TXT

Analysis of embryonic fibroblasts after treatment with fibroblast growth factor 2 (FGF2) at 4, 13, and 40 ng/ml for 24 hours. FGF2 promotes the self-renewal of embryonic stem cells (ESCs) . Results provide insight into the molecular mechanisms underlying ESC self-renewal in response to FGF2.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 agent, 4 dose sets

Platform:

GPL4055

Series:

GSE5437

4 Samples

Download data: TXT

(Submitter supplied) This trancriptome analysis reveals the first detailed analysis on how the remnant lens epithelial cells (LECs) greatly reprogram their transcriptome by 48 hours post cataract surgery (PCS) and the dependence of this phenomenom on endogenous fibronectin gene expression.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL17021

12 Samples

Download data: TSV, TXT

(Submitter supplied) This trancriptome analysis reports genes that are differentially expressed upon deletion of the fibronectin gene from the lens during late embryonic development.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19057

6 Samples

Download data: CSV

(Submitter supplied) Transforming growth factor β (TGFβ) signaling regulates multifaceted reproductive processes via its transmembrane receptor complex-associated machinery. It has been shown that the type 1 receptor of TGFβ (TGFBR1) is indispensable for female reproductive tract development, pregnancy success, and fertility. However, the role of TGFβ signaling in decidual development and function remains poorly defined. more...

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19057

8 Samples

Download data: XLSX

(Submitter supplied) Fetal lung development is a complex biological process, which involves temporal and spatial regulations of many genes. To understand molecular mechanisms of this process, we investigated gene expression profiling of lungs at gestational day 18, 19, 20, 21, new born, and adult rats using in-house rat DNA microarray containing 6,000 known genes and 4,000 ESTs. 1,512 genes passed SAM test and 583 genes (402 known genes and 181 ESTs) had a 2-fold change at least at one time point. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL1699

54 Samples

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(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS2227

Platform:

GPL2987

21 Samples

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(Submitter supplied) The mouse embryonic stem cell’s differentiation was guided by several treatments, and each stage of differentiation was examined. Keywords: development stage

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL2987

12 Samples

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