GEO DataSets

Expression profiling of naïve and memory CD8 T cells from female RAG1-deficient transgenics expressing B6.2.16 T cell receptors specific for the human Y antigen. Genes protecting against programmed cell death upregulated in memory CD8 T cells.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 development stage sets

Platform:

GPL75

Series:

GSE1578

2 Samples

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(Submitter supplied) Naive B6.2.16 CD8 T cells (>85% pure) were isolated from the lymph nodes (LN) of female RAG1-deficient B6.2.16 mice. B6.2.16 CD8 T cell effectors were generated by culturing splenocytes from female RAG1-deficient B6.2.16 mice with HY peptide for 4 d and adoptively transferred into female RAG1-deficient mice. After 200 d, memory B6.2.16 CD8 T cells (>80% pure) were recovered from the spleens and LNs by magnetic bead sorting. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS728 GDS755

Platforms:

GPL75 GPL76

4 Samples

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Expression profiling of naïve and memory CD8 T cells from female RAG1-deficient transgenics expressing B6.2.16 T cell receptors specific for the human Y antigen. Genes protecting against programmed cell death upregulated in memory CD8 T cells.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 development stage sets

Platform:

GPL76

Series:

GSE1578

2 Samples

Download data

(Submitter supplied) CD8 T cells normally differentiate from resting naïve T cells into function effector and then memory CD8 T cells following acute infections. During chronic viral infections, however, virus-specific CD8 T cells often become exhausted. We used microarrays to examine the gene expression differences between naive, effector, memory and exhausted virus-specific CD8 T cells following lymphocytic choriomeningitis virus infection. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platforms:

GPL82 GPL83 GPL81

25 Samples

Download data: CEL