GEO DataSets

Analysis of Mycobacterium tuberculosis (Mt)-infected lung 0 to 21 days after infection. TB immunity is associated with IFNγ lung T helper cell type 1 (Th1) accumulation and Mt-infected macrophage activation. Results provide insight into immune events that occur prior to Th1 accumulation in TB lung.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 2 infection, 4 time sets

Platform:

GPL1261

Series:

GSE23014

16 Samples

Download data: CEL

(Submitter supplied) The lung host immune responses following M.tuberculosis infection in the mouse model of tuberculosis were assayed by studying the gene expression profiles at day 0, day 12, 15 and 21 post infection

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS4257

Platform:

GPL1261

16 Samples

Download data: CEL

(Submitter supplied) A potent Th1 immune response is critical to the control of tuberculosis. The impact of an additive Th2 response on the course of disease has so far been insufficiently characterized, despite increased morbidity after coinfection with Mycobacterium tuberculosis and Th2 eliciting helminths and possible involvement of Th2 polarization in reactivation of latent tuberculosis. Here, we describe the gene expression profile of murine bone marrow derived macrophages alternatively activated by IL-4 to infection with M. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1868

5 Samples

Download data: TIFF

(Submitter supplied) This study was conducted to describe transcriptomic changes of M. tuberculosis during macrophage infection.

Organism:

Mycobacterium tuberculosis H37Rv

Type:

Expression profiling by high throughput sequencing

Platform:

GPL29178

6 Samples

Download data: CSV, TXT

(Submitter supplied) This study was conducted to descripe transcriptomic changes of M.tuberculosis during neutrophil infection

Organism:

Mycobacterium tuberculosis

Type:

Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platform:

GPL27507

6 Samples

Download data: CSV, TXT

(Submitter supplied) Fresh resected lung tissues were obtained from six tuberculosis patients with elevated pulmonary 18F-FDG avidity. Lung tissues with 18F-FDG avidity and nearby uninvolved tissues were profiled with single-cell RNA sequencing.

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24676

11 Samples

Download data: H5, MTX, TSV