Similar studies for GEO DataSets (Select 4138) - GEO DataSets

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Items: 5

Select item 41381.

Proteasomal inhibitor lactacystin effect on cortical neurons in vitro: time course (MG_U74A)

Analysis of cultured cortical neurons treated with 1uM lactacystin for up to 48 hr. Lactacystin induces neuronal apoptosis. Results provide insight into molecular mechanisms underlying proteasomal inhibition-induced neuronal death.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent, 2 time sets

Platform:: GPL32
Series:: GSE22465
4 Samples

Download data: CEL

DataSet

Accession:: GDS4138

ID:: 4138

Select item 2000224652.

Global transcriptomic profiling of lactacystin-mediated neuronal death

(Submitter supplied) Inhibition of proteasome degradation pathway has been implicated in neuronal cell death leading to neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s disease. Pharmacological proteasomal inhibitors such as lactacystin can induce apoptosis in cultured mouse cortical neurons through the activation of caspase-3. Furthermore, proteasomal inhibitors are also reported to mediate deleterious alterations in cell cycle regulation, inflammatory processes and protein aggregation and trigger the cell death pathway. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Datasets:: GDS4138 GDS4140
Platforms:: GPL32 GPL81
10 Samples

Download data: CEL

Series

Accession:: GSE22465

ID:: 200022465

Select item 41403.

Proteasomal inhibitor lactacystin effect on cortical neurons in vitro: time course (MG_U74Av2)

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent, 2 time sets

Platform:: GPL81
Series:: GSE22465
6 Samples

Download data: CEL

DataSet

Accession:: GDS4140

ID:: 4140

Select item 2000369114.

Gene expression levels in immortalized B cells from 131 unrelated CEPH-Utah grandparents treated under ER stress.

(Submitter supplied) We used microarrays to examine gene expression levels from 131 unrelated CEPH-Utah grandparents with either DMSO or tunicamycin.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
262 Samples

Download data: CEL

Series

Accession:: GSE36911

ID:: 200036911

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000369105.

Gene expression levels in immortalized B cells from 95 unrelated CEPH-Utah individuals treated with 10Gy of ionizing radiation

(Submitter supplied) We used microarrays to examine gene expression levels from 95 unrelated CEPH-Utah individuals 0, 2 or 6 hours after treatment with 10Gy of ionizing radiation.