GEO DataSets

Analysis of C57BL/6 testis from day 1 to adult. Determination of transcripts expressed specifically by male germ cells late in spermatogenesis (postmeiotic) reveals many candidates for contraceptive targeting and fertilization participants.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 11 age, 3 tissue sets

Platform:

GPL82

Series:

GSE640

17 Samples

Download data: CEL

(Submitter supplied) A multitude of genes expressed solely in meiotic or postmeiotic spermatogenic cells offers a myriad of contraceptive targets. Understanding mammalian spermatozoan development and the events surrounding fertilization has grown slowly, in part because of uncertainty about the number and identity of the cellular components involved. Determination of those transcripts expressed specifically by germ cells should provide an inclusive list of probable critical proteins. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS401 GDS409 GDS410

Platforms:

GPL82 GPL83 GPL81

51 Samples

Download data: CEL

Analysis of C57BL/6 testis from day 1 to adult. Determination of transcripts expressed specifically by male germ cells late in spermatogenesis (postmeiotic) reveals many candidates for contraceptive targeting and fertilization participants.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 11 age, 3 tissue sets

Platform:

GPL83

Series:

GSE640

17 Samples

Download data: CEL

Analysis of C57BL/6 testis from day 1 to adult. Determination of transcripts expressed specifically by male germ cells late in spermatogenesis (postmeiotic) reveals many candidates for contraceptive targeting and fertilization participants.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 11 age, 3 tissue sets

Platform:

GPL81

Series:

GSE640

17 Samples

Download data: CEL

(Submitter supplied) WIN 18,446/RA treatment of neonatal mice was used to synchronize the initial wave of spermatogenesis and identify novel messages expressed within either germ or Sertoli cells as spermatogonia enter meiosis.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL6246

77 Samples

Download data: CEL

(Submitter supplied) Mammalian spermatogenesis is a complex and highly orchestrated combination of processes in which male germline proliferation and differentiation result in the production of mature spermatozoa. If recent genome-wide studies have contributed to the in-depth analysis of the male germline protein-coding transcriptome, little effort has yet been devoted to the systematic identification of novel unannotated transcribed regions expressed during mammalian spermatogenesis. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL10287

8 Samples

Download data: BED, GTF, TXT

(Submitter supplied) Trout spermatogenesis proceeds seasonally in a way that all morphological and cellular events tend to be synchronized. We thus used gonads at key stages of the male reproductive cycle together with isolated germ cell populations to study the changes in gene expression underlying testis development. Statistical analysis followed by clustering of expression profiles allowed the discrimination of sequential events of gene activation or repression during testis development and/or throughout the germline.

Organism:

Oncorhynchus mykiss

Type:

Expression profiling by array

Platform:

GPL3650

38 Samples

Download data: QTF

(Submitter supplied) Mouse Round Spermatids (Sptd) and Pachytene Spermatocytes (Spcy) Keywords: repeat sample

Organism:

Mus musculus

Type:

Expression profiling by array

Platforms:

GPL1451 GPL1452 GPL1450

9 Samples

Download data

(Submitter supplied) To determine differential gene expression in Ctnnb1 CKO mice testis compared to CTRL mice testis.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL4134

2 Samples

Download data: TXT

(Submitter supplied) MicroRNAs are essential for spermatogenesis. However, the stage‑specific requirements for specific miRNAs in the male mammalian germ line remain largely uncharacterized. The miR‑34 family is, to date, the only miRNA proven to be necessary for the production of sperm in mice, though its germline roles are poorly understood. Here, we generate and analyze paired small RNA and mRNA profiles across different stages of germline development in male mice, focusing on time points shortly before and during meiotic prophase I.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platforms:

GPL17021 GPL13112

20 Samples

Download data: TXT

(Submitter supplied) Gametes rely heavily on post-transcriptional control mechanisms to regulate their differentiation. In eggs, the storage and selective temporal activation of maternal mRNAs is essential for normal development. In the male, transcription ceases during spermiogenesis necessitating the post-transcriptional regulation of many paternal mRNAs required for spermatid differentiation and spermatozoan function. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS2277

Platform:

GPL339

18 Samples

Download data: CEL

Analysis of ribonucleoprotein (RNP) and polysome fractions of prepuberal and adult testes. Protein synthesis occurs on polysomes and translationally inactive mRNAs are sequestered as RNPs. Results provide insight into the translation state of individual mRNAs as spermatogenesis proceeds.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 3 age, 2 development stage, 2 other sets

Platform:

GPL339

Series:

GSE4711

18 Samples

Download data: CEL

(Submitter supplied) Testicular gene expression changes with loss of Topaz1

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL6887

12 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array; Expression profiling by array

Platforms:

GPL6246 GPL16219

15 Samples

Download data: CEL, TXT

(Submitter supplied) Gene expression during spermatogenesis is highly variable and this differential pattern is very important for the successive culmination of different stages of the process, leading to production of the male gamete. Taking the time window of first wave of spermatogenesis, we did a microarray profiling of total testicular transcriptome in mouse and found several significant patterns of variable gene expression, forming upregulated and downregulated clusters among the three stages analyzed here.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL6246

9 Samples

Download data: CEL

(Submitter supplied) Gene expression in mammalian testis undergoing spermatogenesis is under strict post transcriptional regulation and microRNAs are known to play a role in this regulation. Considering the time window of first wave of spermatogenesis, we did a microarray profiling of total testicular microRNAs in mouse and found several significant patterns of variable expression of these molecules during the different stages analyzed here.

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array

Platform:

GPL16219

6 Samples

Download data: TXT

(Submitter supplied) We conducted a genome-wide expression analysis of wild-type males using three cell populations isolated from mitotic, meiotic and post-meiotic phases of spermatogenesis in Drosophila melanogaster. Our approach was to directly isolate testis regions enriched with RNAs from each of the three specific germline phases. We used microarrays to detail the global gene expression profile in spermatogenesis and identified up- and down-regulated genes between two different spermatogenic phases in pairwise comparisons

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL1322

9 Samples

Download data: CEL

(Submitter supplied) Our experimental design includes samples at different time points during the first wave of spermatogenesis. Each time point corresponds to specific cell content in the testis. First time point is post natal day (PND) 7, when only somatic cells and spermatogonia are present in the testis. Thereafter additional cell types are present in selected samples in chronological order: PND 14 contains early spermatocytes, PND 17 late spermatocytes, PND 21 round spermatids and finally PND 28 elongating spermatids. more...

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL14602

12 Samples

Download data: TAB

(Submitter supplied) The sequence of gene regulatory events that drive neonatal germ cell development in the mammalian testis is not yet clear. We assessed changes in mRNA utilization in the neonatal testis at 1 and 4 dpp, times when the testis contains quiescent gonocytes (1 dpp) and proliferating spermatogonia (4 dpp). There are not thought to be major changes in the nature or number of somatic cells over that interval. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

12 Samples

Download data: CEL

(Submitter supplied) LncRNA and mRNA expression profiles in five mouse tissues like brain, heart, kidney, liver and testis and three germ cell-related cell lines such as F9, GC-1 and GC-2

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array

Platform:

GPL24126

24 Samples

Download data: TXT