GEO DataSets

Analysis of 5 and 8 hour embryos from 9 inbred lines. Results provide insight into the extent of gene expression variation in natural populations during early development.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 age, 9 strain sets

Platform:

GPL1322

Series:

GSE8892

36 Samples

Download data: CEL, CHP

(Submitter supplied) Variation in gene expression may underlie many important evolutionary traits. However, it is not known at what stage in organismal development changes in gene expression are most likely to result in changes in phenotype. One widely held belief is that changes in early development are more likely to results in changes in downstream phenotypes. In order to discover how much genetic variation for transcript level is present in natural populations, we studied zygotic gene expression in nine inbred lines of Drosophila melanogaster at two time points in development. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Dataset:

GDS2981

Platform:

GPL1322

36 Samples

Download data: CEL, CHP

(Submitter supplied) The earliest stage of animal development is controlled by maternally deposited mRNA transcripts and proteins. Once the zygote is able to transcribe its own genome, maternal transcripts are degraded, in a tightly regulated process known as the maternal to zygotic transition (MZT). While this process has been well-studied within model species, we have little knowledge of how the pools of maternal and zygotic transcripts evolve. more...

Organism:

Drosophila ananassae; Drosophila erecta; Drosophila miranda; Drosophila sechellia; Drosophila simulans; Drosophila virilis; Drosophila persimilis; Drosophila santomea; Drosophila melanogaster; Drosophila yakuba; Drosophila mauritiana; Drosophila mojavensis; Drosophila pseudoobscura; Drosophila willistoni

Type:

Expression profiling by high throughput sequencing; Third-party reanalysis

14 related Platforms

119 Samples

Download data: TXT

(Submitter supplied) Expression profile comparison of females of D. melanogaster, D. simulans and their hybrid. RNA source: whole body. Keywords: other

Organism:

Drosophila melanogaster; Drosophila simulans

Type:

Expression profiling by array

Platform:

GPL356

21 Samples

Download data

(Submitter supplied) Maternal gene products supplied to the egg during oogenesis drive the earliest events of development in all metazoans. After the initial stages of embryogenesis, maternal transcripts are degraded as zygotic transcription is activated; this is known as the maternal to zygotic transition (MZT). Altering the abundances of maternally deposited factors in the laboratory can have a dramatic effect on development, adult phenotypes and ultimately fitness. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by high throughput sequencing

Platform:

GPL21306

48 Samples

Download data: TXT

(Submitter supplied) Background: The early stages of D. melanogaster embryogenesis involve cell migration and pattern formation, and lead to the formation of three germ layers (the ectoderm, mesoderm and endoderm). These developmental events are controlled by differential gene activity. In the current study we used a suppressive subtractive hybridization (SSH) procedure to identify a group of genes potentially involved in D. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL8228

5 Samples

Download data: TXT

(Submitter supplied) In all animals, the initial events of embryogenesis are controlled by maternal gene products that are deposited into the developing oocyte. At some point after fertilization, control of embryogenesis is transferred to the zygotic genome in a process called the maternal to zygotic transition (MZT). During this time maternal RNAs are degraded and zygotic RNAs are transcribed1. A long standing question has been, what factors regulate these events? The recent findings that microRNAs and Smaugs mediate maternal transcript degradation brought new life to this old problem2,3, however, the transcription factors that activate zygotic gene expression remained elusive. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Dataset:

GDS3477

Platform:

GPL1322

6 Samples

Download data: CEL

Analysis of embryos lacking the zinc finger protein Zelda. Results provide insight into the role of Zelda in the transfer of control of embryogenesis to the zygotic genome during the process of maternal-to-zygotic transition.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL1322

Series:

GSE11231

6 Samples

Download data: CEL

(Submitter supplied) Early embryogenesis is a unique developmental stage where genetic control of development is handed off from mother to zygote. Yet the contribution of this transition to the evolution of gene expression is poorly understood. Here we study two aspects of gene expression specific to early embryogenesis in Drosophila: sex-biased gene expression prior to the onset of canonical X chromosomal dosage compensation, and the contribution of maternally supplied mRNAs. more...

Organism:

Drosophila virilis; Drosophila melanogaster; Drosophila pseudoobscura; Drosophila yakuba

Type:

Expression profiling by high throughput sequencing

4 related Platforms

31 Samples

Download data: TXT

(Submitter supplied) microRNAs play crucial roles in the early development of an organism. However the regulation of transcription through the action of microRNAs during the initial embyonic development has not been studied. We used microarrays to detail the effect of maternal microRNA mir-34 in regulation of zygotic trancription during the initial stages of Zebrafish embryonic development from one cell stage through the maternal-zygotic transition up to 24 hours post fertilization.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL1319

18 Samples

Download data: CEL

(Submitter supplied) We sequenced mRNA from 24 single D. melanogaster embryos (12 male and 12 female) taken from 8 early embryonic timepoints to generate the first sex specific timecourse of gene expression in early Drosophila development

Organism:

Drosophila melanogaster

Type:

Expression profiling by high throughput sequencing

Platform:

GPL9061

24 Samples

Download data: BEDGRAPH, CUFF, SAM

(Submitter supplied) Species-specific regulation of gene expression contributes to the development and maintenance of reproductive isolation and to species differences in ecologically important traits. A better understanding of the evolutionary forces which shape regulatory variation and divergence can be developed by comparing expression differences among species and interspecific hybrids. Once expression differences are identified, the underlying genetics of regulatory variation or divergence can be explored. more...

Organism:

Drosophila simulans; Drosophila melanogaster; Drosophila sp. (in: flies)

Type:

Expression profiling by genome tiling array

Platform:

GPL5919

24 Samples

Download data: BAR, CEL

(Submitter supplied) http://0-www-nature-com.brum.beds.ac.uk/ng/journal/v33/n2/abs/ng1086.html. Little is known about broad patterns of variation and evolution of gene expression during any developmental process. Here we investigate variation in genome-wide gene expression among Drosophila simulans, Drosophila yakuba and four strains of Drosophila melanogaster during a major developmental transition?the start of metamorphosis. Differences in gene activity between these lineages follow a phylogenetic pattern, and 27% of all of the genes in these genomes differ in their developmental gene expression between at least two strains or species. more...

Organism:

Drosophila simulans; Drosophila yakuba; Drosophila melanogaster

Type:

Expression profiling by array

5 related Platforms

48 Samples

Download data

(Submitter supplied) Little is known about broad patterns of variation and evolution of gene expression during any developmental process. Here we investigate variation in genome-wide gene expression among Drosophila simulans, Drosophila yakuba and four strains of Drosophila melanogaster during a major developmental transition-the start of metamorphosis. Differences in gene activity between these lineages follow a phylogenetic pattern, and 27% of all of the genes in these genomes differ in their developmental gene expression between at least two strains or species. more...

Organism:

Drosophila simulans; Drosophila yakuba; Drosophila melanogaster

Type:

Expression profiling by array

Platforms:

GPL227 GPL228

26 Samples

Download data

(Submitter supplied) Drosophila simulans blue gut larvae vs. white prepupae Keywords: repeat sample

Organism:

Drosophila simulans; Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL228

4 Samples

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(Submitter supplied) Drosophila melanogaster Samarkand blue gut larvae vs. white prepupae Keywords: repeat sample

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL228

6 Samples

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(Submitter supplied) Drosophila melanogaster OregonR blue gut larvae vs. white prepupae Keywords: repeat sample

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL228

4 Samples

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(Submitter supplied) Drosophila melanogaster Netherlands2 blue gut larvae vs. white prepupae Keywords: repeat sample

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL228

4 Samples

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(Submitter supplied) Drosophila melanogaster CantonS blue gut larvae vs. white prepupae Keywords: repeat sample

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL228

4 Samples

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(Submitter supplied) Drosophila yakuba white prepupae vs. blue gut larvae Keywords: repeat sample

Organism:

Drosophila melanogaster; Drosophila yakuba

Type:

Expression profiling by array

Platform:

GPL227

4 Samples

Download data