Similar studies for GEO DataSets (Select 2955) - GEO DataSets

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Items: 4

Select item 29551.

Analysis of the stria vascularis (SV) of estrogen-related receptor beta mutants (ERR-beta; NR3B2). Results provide insight into the role of ERR-beta in the development of endolymph-producing cells of the inner ear.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE8434
6 Samples

Download data: CEL

DataSet

Accession:: GDS2955

ID:: 2955

Select item 2000084342.

Transcriptional regulation by Errb (Nr3b2) in stria vascularis

(Submitter supplied) Transcriptional profiles were compared in microdissected lateral walls of the inner ears from Errb mutant mice and wild type littermate controls. The goal is to identify transcriptional targets of Errb and candidate genes for inner ear diseases. Keywords: genetic mutant analysis

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS2955
Platform:: GPL1261
6 Samples

Download data: CEL

Series

Accession:: GSE8434

ID:: 200008434

Select item 2001347563.

Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and Tbx1-nmf219/nmf219 inner ear Transcriptomes

(Submitter supplied) Purpose: The goal of this study is to compare the expression profile of wild type and Tbx1-nmf219/nmf219 mice with NGS-derived inner ear transcriptome profiling (RNA-seq) Methods: inner ear mRNA profiles of E16.5 wild-type (WT) and Tbx1-nmf219/nmf219mice were generated by RNA-seq Results: Using an optimized data analysis workflow, we mapped about 30 million sequence reads per sample to the mouse genome and identified transcripts in the inner ear of WT and Tbx1nmf219/nmf219 mice. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL19057
10 Samples

Download data: XLSX

Series

Accession:: GSE134756

ID:: 200134756

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2002211464.

Single-cell RNA-sequencing of stria vascularis cells in the adult Slc26a4-/- mouse

(Submitter supplied) The primary pathological alternations of SLC26A4-related hearing loss are endolymphatic pH acidification and luminal enlargement of the inner ear. However, the molecular cell type-specific influences remain poorly characterized. In this study, we confirmed a method of isolating single cells in the cochlea's stria vascularis (SV) from wild-type (WT) animals. We then applied it to characterize the distinct transcriptomes from mutant (Slc26a4+/- and Slc26a4-/-) samples. more...