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Links from GEO DataSets

Items: 19

1.
Full record GDS767

RNA-dependent serine/threonine protein kinase PKR overexpression (Mu11K-A)

Analysis of gene expression in NIH3T3 overexpressing RNA-dependent serine/threonine protein kinase (PKR) controlled by a tetracycline repressible promoter. PKR repressed in 1 ug/ml tetracycline and overexpressed upon tetracycline removal. PKR promotes cell survival before inducing cell death.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 protocol sets
Platform:
GPL75
Series:
GSE682
2 Samples
Download data
2.
Full record GDS4186

Lupus nephritis model response to sirolimus-induced mTOR inhibition (Mu11KsubA)

Analysis of kidney from sirolimus-treated NZB/W F1 females at 36 and 42 weeks of age. Sirolimus, a mammalian target of rapamycin (mTOR) inhibitor, has been efficacious in the NZB/W model of lupus nephritis. Results provide insight into role of the mTOR pathway in autoimmune lupus nephritis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 age, 2 agent, 2 disease state sets
Platform:
GPL75
Series:
GSE12024
16 Samples
Download data: CEL
3.
Full record GDS3447

Lung development (Mu11K-A)

Analysis of lungs from embryonic day 12 to adulthood. Results provide insight into the molecular mechanisms governing normal lung development.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 11 age sets
Platform:
GPL75
Series:
GSE10889
11 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS3447
ID:
3447
4.
Full record GDS2661

Various adult tissues (Mu11K-A)

Analysis of various adult tissues, including in white adipose tissue (WAT). The differential expression of genes in WAT was compared to gene expression in differentiating 3T3-L1 preadipocytes (GDS2659).
Organism:
Mus musculus
Type:
Expression profiling by array, count, 5 tissue sets
Platform:
GPL75
Series:
GSE6795
5 Samples
Download data: CEL
DataSet
Accession:
GDS2661
ID:
2661
5.
Full record GDS2659

Adipogenesis in vitro (Mu11K-A)

Analysis of differentiating 3T3-L1 preadipocytes at various time points up to 28 days after induction of adipogenesis using a standard differentiation cocktail of methylisobutylxanthine, dexamethasone, and insulin (MDI). Results provide insight into the molecular mechanisms regulating adipogenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 3 other, 9 time sets
Platform:
GPL75
Series:
GSE6795
10 Samples
Download data: CEL
DataSet
Accession:
GDS2659
ID:
2659
6.
Full record GDS1528

Embryonic fibroblast response to adenoviral vector infection (Mu11K-A)

Analysis of primary C57BL/6 embryonic fibroblasts infected with a 1st generation adenoviral (Ad) vector. Ad vectors are known to induce certain genes and impact innate response networks. Results provide insight into the innate immune response of cells to Ad transduction.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 infection sets
Platform:
GPL75
Series:
GSE3172
12 Samples
Download data
DataSet
Accession:
GDS1528
ID:
1528
7.
Full record GDS1444

Obesity and type 2 diabetes: role of adipogenic gene expression (Mu11K-A)

Analysis of lean (C57BL/6J (B6), BTBR, F1 (B6xBTBR)), obese (B6-ob/ob), and obese-diabetic (F2 (B6xBTBR)-ob/ob [increasingly hyperglycemic], BTBR-ob/ob [severely diabetic]) strains. Results identify decreased adipogenic gene expression in obesity and further changes in the progression to diabetes.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 6 disease state, 6 genotype/variation sets
Platform:
GPL75
Series:
GSE2952
11 Samples
Download data: CEL, EXP
8.
Full record GDS768

RNA-dependent serine/threonine protein kinase PKR overexpression (Mu11K-B)

Analysis of gene expression in NIH3T3 overexpressing RNA-dependent serine/threonine protein kinase (PKR) controlled by a tetracycline repressible promoter. PKR repressed in 1 ug/ml tetracycline and overexpressed upon tetracycline removal. PKR promotes cell survival before inducing cell death.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 protocol sets
Platform:
GPL76
Series:
GSE682
2 Samples
Download data
9.
Full record GDS728

CD8 T cell development (Mu11K-A)

Expression profiling of naïve and memory CD8 T cells from female RAG1-deficient transgenics expressing B6.2.16 T cell receptors specific for the human Y antigen. Genes protecting against programmed cell death upregulated in memory CD8 T cells.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 development stage sets
Platform:
GPL75
Series:
GSE1578
2 Samples
Download data
DataSet
Accession:
GDS728
ID:
728
10.
Full record GDS411

Heart failure and rescue (Mu11K-A)

Analysis of left ventricular (LV) gene expression to uncover genomic changes associated with cardiomyopathy and/or its phenotypic rescue by the beta-adrenergic receptor kinase, betaARKc.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 6 disease state sets
Platform:
GPL75
Series:
GSE670
53 Samples
Download data
DataSet
Accession:
GDS411
ID:
411
11.
Full record GDS387

Cardiac remodeling (Mu11K-A)

Evaluation of in vivo models of cardiac remodeling. Mice underwent transverse aortic constriction (TAC); myocardial infarction (MI) or sham operation. Left ventricle free wall and septum tissues examined 1 week later.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 protocol, 2 tissue sets
Platform:
GPL75
Series:
GSE415
18 Samples
Download data
DataSet
Accession:
GDS387
ID:
387
12.
Full record GDS384

Congenital heart disease - E12.5 (Mu11K-A)

Examination of whole heart of embryonic day 12.5 Csx/Nkx2.5 heterozygous and homozygous embryos to identify downstream target genes and affected pathways of Nkx2.5. Nkx2.5 is a cardiogenic marker with critical function in cardiac differentiation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 strain sets
Platform:
GPL75
Series:
GSE528
13 Samples
Download data
DataSet
Accession:
GDS384
ID:
384
13.
Full record GDS355

Calorie restriction and aging (Mu11K-A)

Investigation of the effect of calorie restriction on the aging process. Gene expression profiles generated for control-fed 5 month, control-fed 30 month and calorie restricted 30 month C57BL/6 mice. Kidney tissue analyzed.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 age, 2 protocol sets
Platform:
GPL75
Series:
GSE459
15 Samples
Download data
DataSet
Accession:
GDS355
ID:
355
14.
Full record GDS285

Ethynyl estradiol estrogen effect in uterus

Temporal examination of ethynyl estradiol (EE) in uterus of immature, ovariectomized C57BL/6. 0.1 mg/kg EE or vehicle administered and uteri harvested at 0, 2, 8, 12, or 24 hours, or three daily doses administered and uteri harvested at 72 hours.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 agent, 6 time sets
Platform:
GPL75
Series:
GSE280
21 Samples
Download data
DataSet
Accession:
GDS285
ID:
285
15.
Full record GDS168

Dietary effects of long chain polyunsaturated fatty acids (Mu11K-A)

Dietary effects of long chain polyunsaturated fatty acids from arachidonate-rich fungal oil and fish oil on hepatic and hippocampal gene expression. Identified broad-spectrum effects on major lipid metabolism transcription factors.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 4 protocol, 2 tissue sets
Platform:
GPL75
Series:
GSE91
8 Samples
Download data
16.
Full record GDS49

Congenital heart disease (Mu11K-A)

Use of E9.5 Csx/Nkx2.5 mutant embryos to identify downstream target genes and affected pathways of Nkx2.5 which has a function in cardiac differentiation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 strain sets
Platform:
GPL75
Series:
GSE78
9 Samples
Download data
DataSet
Accession:
GDS49
ID:
49
17.
Full record GDS47

Granulosa cell tumorigenesis (Mu11K-A)

Comparison of global changes in ovarian transcriptomes uniquely associated with either granulosa cell tumors or luteomas, and identification of new markers for this tumor phenotype. Luteinizing hormone hypersecreting mice studied.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 age, 4 strain sets
Platform:
GPL75
Series:
GSE499
9 Samples
Download data
DataSet
Accession:
GDS47
ID:
47
18.
Full record GDS46

E2F1-regulated genes

Identification of E2F1-regulated genes that modulate the transition from quiescence into DNA synthesis, or have roles in apoptosis, signal transduction, membrane biology, and transcription repression.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 protocol sets
Platform:
GPL75
Series:
GSE498
4 Samples
Download data
DataSet
Accession:
GDS46
ID:
46
19.
Full record GDS45

Cochlear hair cell line differentiation time course (Mu11K-A)

Gene expression profile of differentiation of inner ear hair cell precursors in vitro. A conditionally immortal cell line derived from the mouse cochlea, UB/OC-1, examined from 0 to 14 days.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 12 time sets
Platform:
GPL75
Series:
GSE36
16 Samples
Download data
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