GEO DataSets

Analysis of livers of Fisher F344/N males at 32, 58, and 84 weeks of age. Results provide insight into age-associated changes in the capacity of the liver to metabolize xenobiotic compounds.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, log ratio, 3 age sets

Platform:

GPL890

Series:

GSE4270

38 Samples

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Analysis of testes of males exposed to methoxyacetic acid (MAA) for up to 24 hours. MAA is an in vivo metabolite of ethylene glycol monomethoxy ether, a solvent in industrial and household applications. Results provide insight into the mechanisms underlying the disruption of spermatogenesis by MAA.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, log2 ratio, 2 agent, 4 time sets

Platform:

GPL890

Series:

GSE10032

47 Samples

Download data: TXT

Analysis of cultured cardiomyocytes treated for up to 24 hours with the flavonoid quercetin. Consumption of food rich in quercetin is correlated with a decreased incidence of heart disease. Results provide insight into the molecular mechanisms underlying the cardioprotective effects of quercetin.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, log ratio, 3 time sets

Platform:

GPL890

Series:

GSE7222

6 Samples

Download data: TIFF, TXT

Analysis of primary cardiomyocyte cultures treated with eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA). EPA and DHA are n-3 polyunsaturated fatty acids (PUFAs). Results provide insight into the molecular basis of the cardioprotective effect of n-3 PUFAs.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, log2 ratio, 2 agent sets

Platform:

GPL890

Series:

GSE4327

4 Samples

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Analysis of hearts exposed to the heart toxin bis(2-chloroethoxy)methane (CEM) for 2 or 5 days. Toxicity occurs at day 2 of CEM dosing, and recovery at day 5 despite continued dosing. Results provide insight into the molecular basis of heart toxicity and recovery during the exposure to CEM.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, log2 ratio, 2 time sets

Platform:

GPL890

Series:

GSE4254

12 Samples

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Analysis of isografted kidneys from brain dead donors. Brain death in donors triggers nonspecific inflammatory events that increase the kinetics and intensity of the immunologic response in recipients after kidney transplantation. Results provide insight into the mechanisms underlying this response.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, log10 ratio, 2 disease state, 2 protocol sets

Platform:

GPL890

Series:

GSE5104

12 Samples

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Analysis of peritoneal mesotheliomas induced by various concentrations of o-nitrotoluene (o-NT) or bromochloracetic acid (BCA). o-NT is a high production chemical. BCA is a by-product of drinking water disinfection. Results provide insight into the mechanisms underlying mesothelioma formation.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, log10 ratio, 2 agent, 5 dose sets

Platform:

GPL890

Series:

GSE4682

16 Samples

Download data: TIFF, TXT

Analysis of mammary gland from parous or virgin Lewis animals 3 weeks after treatment with 50 mg/kg of N-methyl-N-nitrosourea, a carcinogen. Full-term pregnancy early in life is associated with a reduced chance of developing breast cancer.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent, 2 development stage sets

Platform:

GPL890

Series:

GSE2726

4 Samples

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Expression profiling of primary cortical neuron cultures exposed to 1 or 3% halothane or 4% isoflurane for 6 hours. Cells allowed to recover for an additional 6 hours. Results provide insight into effect of inhaled anesthetics on global gene expression.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, log ratio, 3 agent, 4 dose sets

Platform:

GPL890

Series:

GSE2982

12 Samples

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