GSM760379[Accession] - GEO DataSets

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Items: 4

Select item 2000306541.

Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and their Differentiated Derivatives

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Methylation profiling by array

Platforms:: GPL8490 GPL6947 GPL13534
675 Samples

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Series

Accession:: GSE30654

ID:: 200030654

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000306532.

Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and their Differentiated Derivatives [Illumina Infinium 27K DNA Methylation]

(Submitter supplied) Human pluripotent stem cells (hPSCs) are potential sources of cells for modeling disease and development, drug discovery, and regenerative medicine. However, it is important to identify factors that may impact the utility of hPSCs for these applications. In an unbiased analysis of 205 hPSC and 130 somatic samples, we identified hPSC-specific epigenetic and transcriptional aberrations in genes subject to X chromosome inactivation (XCI) and genomic imprinting, which were not corrected during directed differentiation. more...

Organism:: Homo sapiens

Type:: Methylation profiling by array

Platform:: GPL8490
283 Samples

Download data: TXT

Series

Accession:: GSE30653

ID:: 200030653

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000084903.

Illumina HumanMethylation27 BeadChip (HumanMethylation27_270596_v.1.2)

(Submitter supplied) HumanMethylation27 DNA Analysis BeadChip allows researchers to interrogate 27,578 highly informative CpG sites per sample at single-nucleotide resolution. This 12-sample BeadChip features content derived from the well-annotated NCBI CCDS database (Genome Build 36) and is supplemented with more than 1,000 cancer-related genes described in published literature. Probe content has been enriched to deeply cover more than 150 well-established cancer genes known to show differential methylation patterns. more...