GSM1396623[Accession] - GEO DataSets

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Items: 4

Select item 2000579281.

Towards epigenetic understanding and therapy of insulin resistance by intranuclear insulin

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by array; Methylation profiling by genome tiling array

Platforms:: GPL15207 GPL1261 GPL13534
24 Samples

Download data: CEL

Series

Accession:: GSE57928

ID:: 200057928

Analyze with GEO2R

Select item 2000578942.

Towards epigenetic understanding and therapy of insulin resistance by intranuclear insulin [DNA methylation]

(Submitter supplied) There is evidence indicating the involvement of DNA methylation memory in maintaining gene expression patterns associated with insulin resistance. Although the exact mechanism remains unknown, it has been proved that insulin resistance is correlated to low heat shock protein (HSP) expression. We reveal that intranuclear insulin can reduce HSP DNA methylation level to up-regulate HSP protein expression and result in long term cure of hyperglycemia.

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL13534
6 Samples

Download data: TXT

Series

Accession:: GSE57894

ID:: 200057894

Analyze with GEO2R

Select item 1000135343.

Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)

(Submitter supplied) 1 difference between HumanMethylation450_15017482_v.1.1.bpm and HumanMethylation450_15017482_v.1.2.bpm: 1.1: 41636384,NEGATIVE,-99,Negative 604 1.2: 41636384,RESTORATION,Green,Restore Protocol: See manufacturer's website