GSM1396617[Accession] - GEO DataSets

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Items: 4

Select item 2000579281.

Towards epigenetic understanding and therapy of insulin resistance by intranuclear insulin

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by array; Methylation profiling by genome tiling array

Platforms:: GPL15207 GPL1261 GPL13534
24 Samples

Download data: CEL

Series

Accession:: GSE57928

ID:: 200057928

Analyze with GEO2R

Select item 2000578932.

Towards epigenetic understanding and therapy of insulin resistance by intranuclear insulin [human cell line gene expression]

(Submitter supplied) There is evidence indicating the involvement of DNA methylation memory in maintaining gene expression patterns associated with insulin resistance. Although the exact mechanism remains unknown, it has been proved that insulin resistance is correlated to low heat shock protein (HSP) expression. We reveal that intranuclear insulin can reduce HSP DNA methylation level to up-regulate HSP protein expression and result in long term cure of hyperglycemia.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL15207
9 Samples

Download data: CEL

Series

Accession:: GSE57893

ID:: 200057893

Analyze with GEO2R

Select item 1000152073.

[PrimeView] Affymetrix Human Gene Expression Array

(Submitter supplied) July 10, 2019: annotation table updated with netaffx build 36 Protocol: See details from Affymetrix. This is a commercially available chip.