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Items: 10

1.

Chromosomal deletions linked to p53 loss of heterozygosity promote cancer through p53-independent mechanisms

(Submitter supplied) The purpose of current study is to identify the differentiated gene expression associated with mouse 11B3 deletion, syntenic to human chromosome 17p13.1. We compared four different mouse acute myeloid leukemia cells, freshly isolated from mouse bone marrows with either 11B3fl/p53fl;shNf1;shMll3;Vav1-Cre or p53fl/fl;shNf1;shMll3;Vav1-Cre. The RNA-seq results indicate that genes located on chromosome 11B3 mostly reduce gene expression level in 11B3 deleted leukemia cells.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
8 Samples
Download data: TXT, XLS
Series
Accession:
GSE69654
ID:
200069654
2.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
3.

p53fl/fl rep4

Organism:
Mus musculus
Source name:
acute myeloid cells
Platform:
GPL17021
Series:
GSE69654
Download data: TXT
Sample
Accession:
GSM1705364
ID:
301705364
4.

p53fl/fl rep3

Organism:
Mus musculus
Source name:
acute myeloid cells
Platform:
GPL17021
Series:
GSE69654
Download data: TXT
Sample
Accession:
GSM1705363
ID:
301705363
5.

p53fl/fl rep2

Organism:
Mus musculus
Source name:
acute myeloid cells
Platform:
GPL17021
Series:
GSE69654
Download data: TXT
Sample
Accession:
GSM1705362
ID:
301705362
6.

p53fl/fl rep1

Organism:
Mus musculus
Source name:
acute myeloid cells
Platform:
GPL17021
Series:
GSE69654
Download data: TXT
Sample
Accession:
GSM1705361
ID:
301705361
7.

11B3fl/p53fl rep4

Organism:
Mus musculus
Source name:
acute myeloid cells
Platform:
GPL17021
Series:
GSE69654
Download data: TXT
Sample
Accession:
GSM1705360
ID:
301705360
8.

11B3fl/p53fl rep3

Organism:
Mus musculus
Source name:
acute myeloid cells
Platform:
GPL17021
Series:
GSE69654
Download data: TXT
Sample
Accession:
GSM1705359
ID:
301705359
9.

11B3fl/p53fl rep2

Organism:
Mus musculus
Source name:
acute myeloid cells
Platform:
GPL17021
Series:
GSE69654
Download data: TXT
Sample
Accession:
GSM1705358
ID:
301705358
10.

11B3fl/p53fl rep1

Organism:
Mus musculus
Source name:
acute myeloid cells
Platform:
GPL17021
Series:
GSE69654
Download data: TXT
Sample
Accession:
GSM1705357
ID:
301705357
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Supplemental Content

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