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Items: 9

1.

Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells

(Submitter supplied) This study characterizes the genome-side occupancy of AML1, AML1-ETO and the cofactors N-CoR and p300 in leukemics cells (Kasumi-1) to discover novel regulatory mechanisms involving genes bound by the t(8:21) fusion protein AML1-ETO. A significant discovery of our study is the co-localization of AML1-ETO with the N-CoR co-repressor on genomic regions that are primarily distal to the transcriptional start sites (TSSs). more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL9115
7 Samples
Download data: BED, BW
Series
Accession:
GSE62847
ID:
200062847
2.

Illumina Genome Analyzer II (Homo sapiens)

Platform
Accession:
GPL9115
ID:
100009115
3.

Control

Organism:
Homo sapiens
Source name:
Kasumi-1_input
Platform:
GPL9115
Series:
GSE62847
Download data
Sample
Accession:
GSM1534447
ID:
301534447
4.

H3K27me3

Organism:
Homo sapiens
Source name:
Kasumi-1_ChIP
Platform:
GPL9115
Series:
GSE62847
Download data: BW
Sample
Accession:
GSM1534446
ID:
301534446
5.

H3K4me3

Organism:
Homo sapiens
Source name:
Kasumi-1_ChIP
Platform:
GPL9115
Series:
GSE62847
Download data: BED
Sample
Accession:
GSM1534445
ID:
301534445
6.

p300

Organism:
Homo sapiens
Source name:
Kasumi-1_ChIP
Platform:
GPL9115
Series:
GSE62847
Download data: BED
Sample
Accession:
GSM1534444
ID:
301534444
7.

N-CoR

Organism:
Homo sapiens
Source name:
Kasumi-1_ChIP
Platform:
GPL9115
Series:
GSE62847
Download data: BED
Sample
Accession:
GSM1534443
ID:
301534443
8.

AML1-ETO

Organism:
Homo sapiens
Source name:
Kasumi-1_ChIP
Platform:
GPL9115
Series:
GSE62847
Download data: BED
Sample
Accession:
GSM1534442
ID:
301534442
9.

AML1

Organism:
Homo sapiens
Source name:
Kasumi-1_ChIP
Platform:
GPL9115
Series:
GSE62847
Download data: BED
Sample
Accession:
GSM1534441
ID:
301534441
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Supplemental Content

db=gds|term=GSE62847[Accession]|query=1|qty=2|blobid=MCID_66354b4f679af6518b733a4e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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