GEO DataSets

(Submitter supplied) Recurrent mutations in histone modifying enzymes in multiple cancer types imply key roles in tumorigenesis. However, the functional relevance of these mutations remains unknown. Here we show that the JARID1B histone H3 lysine 4 demethylase is frequently amplified and overexpressed in luminal breast tumors and a somatic point mutation of JARID1B leads to the gain of luminal-specific gene expression programs. more...

Organism:

Homo sapiens

Type:

Methylation profiling by genome tiling array

Platform:

GPL13534

5 Samples

Download data: TXT

(Submitter supplied) 1 difference between HumanMethylation450_15017482_v.1.1.bpm and HumanMethylation450_15017482_v.1.2.bpm: 1.1: 41636384,NEGATIVE,-99,Negative 604 1.2: 41636384,RESTORATION,Green,Restore Protocol: See manufacturer's website

Organism:

Homo sapiens

1671 Series

1 Related Platform

117793 Samples

Download data: BPM, CSV, TXT, XLSX