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Select item 53181.

Full record GDS5318

Drug efflux transporter ABCB5 knockdown effect on G3361 melanoma cells

Analysis of pigmented melanoma G3361 cell line following ABCB5 ablation. ABCB5 [ATP-binding cassette, subfamily B (MDR/TAP), member 5] is a drug efflux transporter shown to be highly overexpressed in diverse human cancers. Results provide insight into the role of ABCB5 in melanoma.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 protocol sets

Platform:: GPL571
Series:: GSE38290
6 Samples

Download data: CEL, EXP, TXT

DataSet

Accession:: GDS5318

ID:: 5318

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 53172.

Full record GDS5317

Drug efflux transporter ABCB5 knockdown effect on A375 melanoma cells

Analysis of nonpigmented melanoma A375 cell line following ABCB5 ablation. ABCB5 [ATP-binding cassette, subfamily B (MDR/TAP), member 5] is a drug efflux transporter shown to be highly overexpressed in diverse human cancers. Results provide insight into the role of ABCB5 in melanoma.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 protocol sets

Platform:: GPL571
Series:: GSE38290
6 Samples

Download data: CEL, EXP, TXT

DataSet

Accession:: GDS5317

ID:: 5317

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 52863.

Full record GDS5286

Monocyte-derived dendritic cells from young and aged donors

Comparison of dendritic cells (DCs) from young (20 to 27 years) and aged (77 to 87 years) donors. DCs are antigen-presenting cells important in initiating and regulating innate and adaptive immune responses. Results provide insight into the molecular basis of the decline in DC function with age.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 age sets

Platform:: GPL571
Series:: GSE58015
9 Samples

Download data: CEL

DataSet

Accession:: GDS5286

ID:: 5286

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 56694.

Full record GDS5669

WHO grade IV primary glioblastoma of long-term survivors

Analysis of 7 patients with glioblastoma (GBM) treated at Memorial Sloan-Kettering Cancer Center, with survival > 48 months. These long-term survivors (LTSs) represent proneural, neural, classical, and mesenchymal subtypes of GBM. Results provide insight into molecular characteristics of GBM LTSs.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 4 disease state, 7 individual, 7 time sets

Platform:: GPL571
Series:: GSE54077
7 Samples

Download data: CEL

DataSet

Accession:: GDS5669

ID:: 5669

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 54455.

Full record GDS5445

E3 ubiquitin ligase PARK2 depletion effect on SF539 glioma cell line

Analysis of SF539 glioma cells depleted for PARK2. PARK2 is an E3 ubiquitin ligase. Results provide insight into the role of PARK2 in the coordinate control of cyclins in cell cycle regulation and tumor suppression.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 agent sets

Platform:: GPL571
Series:: GSE50864
6 Samples

Download data: CEL

DataSet

Accession:: GDS5445

ID:: 5445

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 54446.

Full record GDS5444

E3 ubiquitin ligase PARK2 depletion effect on SNB19 glioma cell line

Analysis of SNB19 glioma cells depleted for PARK2. PARK2 is an E3 ubiquitin ligase. Results provide insight into the role of PARK2 in the coordinate control of cyclins in cell cycle regulation and tumor suppression.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 agent sets

Platform:: GPL571
Series:: GSE50864
6 Samples

Download data: CEL

DataSet

Accession:: GDS5444

ID:: 5444

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 56357.

Full record GDS5635

Chlamydia Type III secretion effector TepP-deficient mutant infection of endocervical epithelial cells in vitro

Analysis of A2EN endocervical epithelial cells infected with a Chlamydia trachomatis mutant strain lacking type III secretion effector TepP (Ct875) or its complemented counterpart for 4hr. Results provide insight into the impact of effector protein TepP on the host cell molecular response.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 infection sets

Platform:: GPL571
Series:: GSE54336
6 Samples

Download data: CEL

DataSet

Accession:: GDS5635

ID:: 5635

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 48978.

Full record GDS4897

Skeletal muscle of patients with inherited insulin resistance

Analysis of muscle from patients with a mutation (Arg1174Gln) in the tyrosine kinase domain of the insulin receptor gene (INSR). This mutation is associated with inherited insulin resistance. Results provide insight into molecular mechanisms underlying insulin resistance in skeletal muscle.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL571
Series:: GSE36297
16 Samples

Download data: CEL

DataSet

Accession:: GDS4897

ID:: 4897

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 50769.

Full record GDS5076

PIAS1 SUMO ligase depletion effect on breast cancer cell line

Analysis of MDA-MB231 breast cancer cells depleted for PIAS1. PIAS1 is a SUMO ligase. Results provide insight into the role of PIAS1 in breast tumorigenesis.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 growth protocol, 2 protocol sets

Platform:: GPL571
Series:: GSE44024
4 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS5076

ID:: 5076

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 487510.

Full record GDS4875

Proliferator-activated receptor gamma agonist rosiglitazone effect on extravillous cytotrophoblasts in vitro

Analysis of EVCTs isolated from first trimester placenta and treated with rosiglitazone, a PPARγ agonist. EVCT invasion into the uterus is critical for placental and fetal development. Results provide insight into the molecular basis of PPARγ-mediated regulation of EVCT invasion in vitro.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent sets

Platform:: GPL571
Series:: GSE28426
10 Samples

Download data: CEL

DataSet

Accession:: GDS4875

ID:: 4875

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 533911.

Full record GDS5339

Endometriosis: ectopic and eutopic endometrium

Analysis of ectopic endometria and eutopic endometria from endometriosis patients. Endometriosis is characterized by the presence of endometrial tissue at extra-uterine sites. Results provide insight into the molecular mechanisms underlying endometriosis pathogenesis.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state, 3 tissue sets

Platform:: GPL571
Series:: GSE25628
22 Samples

Download data: CEL

DataSet

Accession:: GDS5339

ID:: 5339

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 489112.

Full record GDS4891

Discoid lupus erythematosus and psoriasis skin biopsies

Analysis of discoid lupus erythematosus (DLE) and psoriasis skin samples. DLE is the most common skin manifestation of lupus; psoriasis is the most well-characterized autoimmune skin disease to date. Results provide insight into the molecular mechanisms underlying DLE skin.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 disease state, 2 other sets

Platform:: GPL571
Series:: GSE52471
38 Samples

Download data: CEL

DataSet

Accession:: GDS4891

ID:: 4891

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 487113.

Full record GDS4871

Donor lymphocyte infusion effect on bone marrow-infiltrating CD3+ T cells of patients with relapsed chronic myelogenous leukemia

Analysis of marrow-infiltrating CD3+ T cells isolated from relapsed chronic myelogenous leukemia (CML) patients following donor lymphocyte infusion (DLI) therapy. Four patients were DLI-responsive, two were DLI-nonresponsive. Results provide mechanistic insights into DLI response in relapsed CML.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 individual, 2 protocol sets

Platform:: GPL571
Series:: GSE49067
12 Samples

Download data: CEL

DataSet

Accession:: GDS4871

ID:: 4871

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 496214.

Full record GDS4962

Transcription factor ETS fusion EWS/FLI1 knockdown in Ewing sarcoma cell line: time course

Analysis of A673 Ewing Sarcoma cell line for up to 96hrs after inducible EWSR1/FLI1 knockdown. Oncogenic ETS fusions are driver mutations in diverse cancers, including Ewing sarcoma. Results provide insight into the molecular mechanisms underlying ETS-driven tumorigenesis.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 protocol, 6 time sets

Platform:: GPL571
Series:: GSE27524
16 Samples

Download data: CEL

DataSet

Accession:: GDS4962

ID:: 4962

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 498915.

Full record GDS4989

PGC1alpha depletion effect on melanoma cell line

Analysis of A375P melanoma cells depleted for PGC1alpha. PGC1alpha is a transcriptional coactivator that promotes mitochondrial biogenesis and respiration. A375P is a cell line that overexpresses PGC1alpha. Results provide insight into the role of PGC1alpha in melanoma.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 protocol sets

Platform:: GPL571
Series:: GSE36879
8 Samples

Download data: CEL

DataSet

Accession:: GDS4989

ID:: 4989

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 515416.

Full record GDS5154

FAT1 depletion effect on astrocyte and glioma cell lines

Analysis of astrocyte and glioma cells depleted for FAT1. FAT1 encodes a cadherin-like protein. Results provide insight into the role of FAT1 in cancer development.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 cell line, 2 cell type, 2 protocol sets

Platform:: GPL571
Series:: GSE40583
18 Samples

Download data: CEL

DataSet

Accession:: GDS5154

ID:: 5154

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 435317.

Full record GDS4353

Cerebral Palsy: skeletal muscle biopsies

Analysis of gracilis and semitendinosus muscle biopsies from pediatric cerebral palsy (CP) patients. Muscles from CP patients are spastic and form contractures limiting range of motion and joint function. Results provide insight into molecular basis of skeletal muscle response to CP.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state, 2 tissue sets

Platform:: GPL571
Series:: GSE31243
40 Samples

Download data: CEL

DataSet

Accession:: GDS4353

ID:: 4353

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 459718.

Full record GDS4597

In vitro model for inflammatory dendritic cells

Analysis of an in vitro model of peptidoglycan-activated monocytes as inflammatory myeloid dendritic cells (DCs). DCs are thought to have an important role in the pathogenesis of inflammatory skin lesions such as psoriasis. Results provide insight into molecular basis of psoriasis pathogenesis.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 5 agent sets

Platform:: GPL571
Series:: GSE42305
15 Samples

Download data: CEL

DataSet

Accession:: GDS4597

ID:: 4597

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 440119.

Full record GDS4401

H9 hESC-derived neural stem cells harboring pathogenic leucine-rich repeat kinase 2 mutation

Analysis of LRRK2 (Gly2019Ser) mutant neural stem cells (NSC) treated with LRRK2 kinase specific inhibitor LRRK2-IN-1. The LRRK2 (G2019S) mutation causes familial Parkinson's disease. Results provide insight into molecular basis of progressive degeneration of NSCs caused by pathogenic LRRK2.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent, 2 genotype/variation sets

Platform:: GPL571
Series:: GSE36321
9 Samples

Download data: CEL

DataSet

Accession:: GDS4401

ID:: 4401

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 440020.

Full record GDS4400

Fibroblast-derived induced pluripotent stem cells harboring pathogenic leucine-rich repeat kinase 2 mutation

Analysis of IPSCs generated from LRRK2 (Gly2019Ser) mutation-bearing patient fibroblasts by cell reprogramming. The LRRK2 (G2019S) mutation causes familial Parkinson's disease (PD). Results provide insight into the molecular mechanisms underlying PD.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 cell type, 3 genotype/variation sets

Platform:: GPL571
Series:: GSE33298
14 Samples

Download data: CEL

DataSet

Accession:: GDS4400

ID:: 4400

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

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