5SYN_B 11 LTDAATVSGAERETAAVIFLHGLGDTG-----HSWADALS-TIRLPHVKYICPHAPR-IPVTLNMKMVMPSWFDLMGLSP 83 human Q21224 6 NGNPSIVSPRGEHKGTLIFLHGLGDQG-----HGWADAFKtEAKHDNIKFICPHSSE-RPVTLNMGMRMPAWFDLFGLDP 79 Caenorhabditis elegans O18501 18 LP-AAVVASRSKHSATLIFLHGLGDTG-----HGWSDALK-EYVPDYFKIICPHANS-IPVTLNGGMCMPAWYDIYALSE 89 Schistosoma mansoni O77821 11 P---AVVPAARKATAAVIFLHGLGDTG-----HGWAEAFA-GIKSPHIKYICPHAPV-MPVTLNMNMAMPSWFDIVGLSP 80 rabbit Q12354 1 MNGLRVAAKIQPARQTIIFLHGLGDTGsgwgfLAQYLQQRdPAAFQHTNFVFPNAPE-LHVTANGGALMPAWFDILEWDP 79 Saccharomyces cerevis... O42881 6 N--SVIINPSVAHTATVIFLHGLGDSG-----QGWSFMANtWSNFKHIKWIFPNAPS-IPVTVNNGMKMPAWYDIYSFAD 77 Schizosaccharomyces p... O14304 11 NACAEIIEGKDKVHNVVILMHGLGDSH-----KSFANMAK-NVPLPNTSYISLRGPYrLPLDFENPGGNWMWGEDVHFDQ 84 Schizosaccharomyces p... O84138 11 AGIEFIECPGDPEAPVIIFCHGYGASAd----HLTFFPTMcVCANLRPTWVFPHGIE-QLPYQLGGGR--AWFPLDTVLF 83 Chlamydia trachomatis O05958 5 LEYPEVESKELPPQKLVVLLHGVGSDGh----DLIGLVPYiKNDLPNCHFISPHGIE-DYDMMPYGR---QWFSLRDRSP 76 Rickettsia prowazekii... P76561 3 HDHFVVQSPDKPAQQLLLLFHGVGDNP-----VAMGEIGNwFAPLFPDALVVSVGGA-EPSGNPAGR---QWFSVQGITE 73 Escherichia coli K-12
5SYN_B 84 DA--PEDEAGIKKAAENIKALIEHEMKNG------------IPANRIVLGGFSQGGALSLYTALTCPH--PLAGIVALSC 147 human Q21224 80 NA--QEDEQGINRATQYVHQLIDAEVAAG------------IPASRIAVGGFSMGGALAIYAGLTYPQ--KLGGIVGLSS 143 Caenorhabditis elegans O18501 90 NA--KQDEAGIKEASLELGKFVDAEIKAG------------VPIGNIVIGGFSQGGSVALYNALTSTL--QYGGVVAFSC 153 Schistosoma mansoni O77821 81 DS--QEDESGIKQAAETVKALIDQEVKNG------------IPSNRIILGGFSQGGALSLYTALTTQQ--KLAGVTALSC 144 rabbit Q12354 80 SFs-KVDSDGFMNSLNSIEKTVKQEIDKG------------IKPEQIIIGGFSQGAALALATSVTLPW--KIGGIVALSG 144 Saccharomyces cerevis... O42881 78 MK--REDENGILRSAGQLHELIDAELALG------------IPSDRILIGGFSQGCMVSLYAGLTYPK--RLAGIMGHSG 141 Schizosaccharomyces p... O14304 85 NGe-LQSEADFSKSFTMISNLIGNLLSYG------------ILSSRIFFFGFGQGAMVALYSCYKLSTkyQLGGIFSFGG 151 Schizosaccharomyces p... O84138 84 EKliSSQE-ITPDTDRLYQQLLDVDFEKPkqalegliheleRDRSEVIIGGFSQGAMMTTHLMLSSRL--PYRGALICSG 160 Chlamydia trachomatis O05958 77 HI----IAKLIANNISKLEDIIREKQTELn-----------LTNKDTVIIGFSQGTIIGLYLTLIQQK--PLFCTIGFSG 139 Rickettsia prowazekii... P76561 74 DN----RQARVDAIMPTFIETVRYWQKQSg-----------VGANATALIGFSQGAIMVLESIKAEPG--LASRVIAFNG 136 Escherichia coli K-12
5SYN_B 148 WLPLHRAFPQAANGSAk--DLAILQCHGELDPMVPVRFGALTAEKLRSVVTpaRVQFKTYPGVMHSSCPQEMAAVKEFLE 225 human Q21224 144 FFLQRTKFPGSFTANN---ATPIFLGHGTDDFLVPLQFGQMSEQYIKKFNP--KVELHTYRGMQHSSCGEEMRDVKTFLS 218 Caenorhabditis elegans O18501 154 WLPLHTKFMSSPTLLTmpkDVPVFQCHGLEDYTIPFAMGKLTHELLKTFQLs-KCELNCYPQLSHSSCEKEMGDLRTFLS 232 Schistosoma mansoni O77821 145 WLPLRASFSQGPINSAn-rDISVLQCHGDCDPLVPLMFGSLTVERLKALINpaNVTFKIYEGMMHSSCQQEMMDVKHFID 223 rabbit Q12354 145 FCSIPGILKQHKNGINv--KTPIFHGHGDMDPVVPIGLGIKAKQFYQDSCEiqNYEFKVYKGMAHSTVPDELEDLASFIK 222 Saccharomyces cerevis... O42881 142 FLPLASKFPSALSRVAk--EIPILLTYMTEDPIVPSVLSSASAKYLINNLQl-KCLDRPFEGDAHSLSSESFMAMYKFTQ 218 Schizosaccharomyces p... O14304 152 TLPLSITLPNHPFHVPv--YLFEKRLHCSCSEYEESRLRKTFKPFHLTCWN--RDDKTDMP-SSPREWYTFVQSISKHLY 226 Schizosaccharomyces p... O84138 161 AAVPNQSWEENASLCG---KTPYIQSHGYDDPILPYFLGERLYKVLTASLK---GEMVSFH-GGHEIPVVMMQKIQESIA 233 Chlamydia trachomatis O05958 140 ALIPPMKVN---NKLT-----PICLIHGELDQVINVSEMYNASNYLSKLNI--EHSGHKLTSLAHSIDGRGLEIAINFIN 209 Rickettsia prowazekii... P76561 137 RYASLPETAS--TATT------IHLIHGGEDPVIDLAHAVAAQEALISAGG--DVTLDIVEDLGHAIDNRSMQFALDHLR 206 Escherichia coli K-12
5SYN_B 226 KLL 228 human Q21224 219 AHI 221 Caenorhabditis elegans O18501 233 KNI 235 Schistosoma mansoni O77821 224 KLL 226 rabbit Q12354 223 KSL 225 Saccharomyces cerevisiae S288C O42881 219 TVI 221 Schizosaccharomyces pombe 972h- O14304 227 IHN 229 Schizosaccharomyces pombe 972h- O84138 234 LWS 236 Chlamydia trachomatis O05958 210 TCH 212 Rickettsia prowazekii str. Madrid E P76561 207 YTI 209 Escherichia coli K-12
Jiyao W et al.(2023). "The conserved domain database in 2023.",