Conserved Protein Domain Family
PRK00772

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PRK00772: PRK00772 
3-isopropylmalate dehydrogenase; Provisional
Statistics
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PSSM-Id: 234832
Aligned: 631 rows
Threshold Bit Score: 392.157
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
158421928   2 ATHKLLLLAGDGIGPEVMAEVKHVIGFL-DKQGIASFAIEEDLVGGSAYDAHGVAISDAAMERAKAADAILLGAVGGPKW 80 
241113365   2 KTYKIALLPGDGIGRDVTAAAWAVLEKT-ARLNGFSLDATSYPWSCDYYLENGSMMPADGIETLRSFDAILLGAVGWPR- 79 
209547315   2 KTYRIALLPGDGIGRDVTEAAKAVLEKA-AARNGFSLATTSYPWSCDYYLENGSMMPDNGIETLRSFDAILLGAVGWPR- 79 
116249294   2 KTYKIALLPGDGIGRDVTAAAWAVLEKA-ARLNGFSLDATSYPWSCDYYLENGSMMPADGIEILRSFDAILLGAVGWPR- 79 
86361069    2 KTYRIALLPGDGIGRDVTDAAWAVLEKT-AGSGGFSLEATRYPWSCDYYLENGSMMPADGIETLKSFDAILLGAVGWPR- 79 
190894878   2 KTYKIALLPGDGIGRDVTEAAWSVLEKT-AGSSGFSLQATRLPWSCDYYLENGSMMPADGIETLRSFDAILLGAVGWPR- 79 
77404601    3 RRHAVALIPGDGIGPEVIDASLEVLEKV-ARLHGFALDMTRFDWSCDRYLATGRMMPEDGIDQLRPHAAILLGAVG---W 78 
221218241   3 RRHAVALIPGDGIGPEVIDASLEVLEKA-ASVHGFALDMTRFDWSCDRYLATGRMMPEDGIDQLRPHAAILLGAVG---W 78 
14520655    1 -MYRVAVIKGDGIGPEVVDSAIRVVNSVtD-----RIRFYEFEGGFEVFKRIGSPISEDDLKEIRKMDAILFGATTTPF- 73 
228917966   1 -MYKVAVIKGDGIGPEVIDAAIRVVKSVtD-----KIKFYEFEGGLSVFKKYGVPIREEDLEEIRKMDAILFGATTTPF- 73 
158421928  81 ANVPYEARPEAG-LLRLRKDLGLFANLRPALCYPALADASSLKREvveGLDILIVRELTGGVYFGEP-KTILdlgnGQRR 158
241113365  80 --KVPDSVSLHGlLLPIRKAFVQYANIRPHRLLPGVQG--PLRSD---GFDILCIRENTEGEYSGAG-GRVHqg-tDNEV 150
209547315  80 --KVPDSVSLHGlLLPIRKAFVQYANIRPHRLLPGVQG--PLRSE---NFDILCIRENTEGEYSGAG-GRVHqg-tDSEV 150
116249294  80 --KVPDSVSLHGlLLPIRKAFVQYANIRPHRLLPGVQG--PLRSD---GFNILCIRENTEGEYSGAG-GRVHqg-tDNEV 150
86361069   80 --KVPDSVSLHGlLLPIRKAFVQYANIRPHRLLPGVQG--PLRSD---GFDILCIRENTEGEYSGAG-GRIHqg-aDNEV 150
190894878  80 --KVPDSVSLHGlLLPIRKAFVQYANIRPHRQLPGVQG--PLRSD---GFDILCIRENTEGEYSGAGgRVHQg--tDNEV 150
77404601   79 PARVPDAVSLHGlLLPIRKSFDQFANMRPHRLLPG--ATGPLKSE---AFDILCIRENTEGEYSGAG--GRIhvgtPAEV 151
221218241  79 PARVPDSVSLHGlLLPIRKSFDQFANMRPHRLLPG--ATGPLKSE---AFDILCIRENTEGEYSGAG-GRIHvg-tPAEV 151
14520655   74 -----NVPGYRSlIVTLRKELDLYANLR---IIPDLSN----------GKEIVIVRENTEGLYARDG-IGFS------DR 128
228917966  74 -----DVPRYKSlIITLRKELDLYANLRIIPNFKL-------------RKEIIIVRENSEGLYSGEGa-------yDSNK 128
158421928 159 AIDTQVYDTYEIDRIGRVAFELARTRRNKVTSSEKHNVMRSG-VLWKETITALHAkDYKDVELEHQLADSLAMQLVRWPK 237
241113365 151 AVETSIFTRTGVERILRFGFEQARTRRGKLASVTKSNAQKYSmVFWDEITQKLSL-EYPDIEVTSYHIDAMAARMVMAPD 229
209547315 151 AVETSIFTRQGVERILRFGFEQARARRGKLASVTKSNAQRYSmVFWDEITQRLSQ-DYPDVEVTSYHIDAMAARMVMAPE 229
116249294 151 AVETSIFTRKGVERILRFGFEQARARRGKLASVTKSNAQKYSmVFWDEITQRLSA-EYPDVEVTSYHIDAMAARMVMAPD 229
86361069  151 AIETAIFTRKGVERILRFGFEQARARRGKLASVTKSNAQKYSmVFWDEITHGLSA-EYPDVEVTSYHIDAMAARMVMAPE 229
190894878 151 AIETAIFTRKGVERILRFGFEQARARRGKLASVTKSNAQKYSmVFWDEITHGLAA-EYPDVEVTSYHIDAMAARMVMAPD 229
77404601  152 AVETSIFTRRGVERILRFGFEQARRRSGRLASVTKSNAQKYSmVFWDEVTEEVAA-DYPDVTVSRYHIDAIAARMVMAPE 230
221218241 152 AVETSIFTRRGVERILRFGFEQARRRSGRLASVTKSNAQKYSmVFWDEVTEEVAA-DYPDVTVSRYHIDAIAARMVMAPE 230
14520655  129 AIDFRIITLEGARRIAKFAINLAKERNSFITFVHKANVLKGD-RFFREIVLEIAE--REGVEVREAIIDSFMIKLVKNPW 205
228917966 129 VVDFRIITRKGAERIAKFAVKLAKDRSTFLTFVHKANILESD-RFFRKIVLDIAR--KEDVKVREEIVDSFTIKLVKDPW 205
158421928 238 QFDVIVTDNLFGDILSDIASMLTGSLGMLPSASLGaldeatGKRPAMYEPVHGSAPDIAGRGIANPIAMIGSLGMALRYs 317
241113365 230 SLDVVVASNLFGDILTDLGAAIQGGLGFAASANINp----dRSAPSMFEPVHGSAPDIAELGIANPIAAIWSGAMMLEH- 304
209547315 230 SLDVVVASNLFGDILTDLGAAIQGGLGFAASANINp----dRSTPSMFEPVHGSAPDIAHLGIANPIAAIWSGAMMLEH- 304
116249294 230 SLDVVVASNLFGDILTDLGAAIQGGLGFAASANINp----dRSAPSMFEPVHGSAPDIADLGIANPIAAIWSGAMMLEH- 304
86361069  230 SLDVVAASNLFGDILTDLGAAIQGGLGFAASANINp----dRSAPSMFEPVHGSAPDIAHLGIANPIAAIWSGAMMLEH- 304
190894878 230 SLDVVVASNLFGDILTDLGAAIQGGLGFAASANINp----dRSAPSMFEPVHGSAPDIAHLGIANPIAAIWSGAMMLEH- 304
77404601  231 TLDVVVASNLFGDILTDLGAAIQGGLGFAPSANINp----dRSQPSMFEPVHGSAPDIAGRGIANPVATLWSAALMLDH- 305
221218241 231 TLDVVVASNLFGDILTDLGAAIQGGLGFAPSANINp----dRSQPSMFEPVHGSAPDIAGRGIANPVATLWSAALMLDH- 305
14520655  206 DHGVILTENMFGDIISDLATIHAGSIGIVPSGNYG-------DEIALFEPIHGSAPDIAGKGIANPIGAILSAAMMLDY- 277
228917966 206 NLGIILSENMFGDILSDLATIHAGSIGIVPSGNYG-------EDIALFEPIHGSAPDIAGKGIANPIGAILSAAMMLDY- 277
158421928 318 FGLGEVADKIEEAIAAVLASG--KRTGDIrtpGGPVIGTADMGAAIVEELG 366
241113365 305 LGETAAAARVMASIEATTARG--IGA------IPGKDKTDAITASVLSALG 347
209547315 305 LGEPGAAGKVMAAIEATTARGig--------aSPGRDKTDAITASVLSALD 347
116249294 305 LGEPAAAARVMASIEATTARG----IGSI----PGKDKTDAITASVLSALG 347
86361069  305 LGETAAAEKVMDAIETTTARG----VGAI----PGKDRTDAITASVLSALG 347
190894878 305 LGETAAAGKVMAAIETTTARG------------IGAIPGKDKTDAITASVL 343
77404601  306 LGEEAAGRSLLAALSAVTAEGr-LRTPDQ----GGRACTTDVARAVADRLS 351
221218241 306 LGEEAAGRSLLAALSAVTAEGrlRTPDQ-----GGRACTTDVARAVADRLS 351
14520655  278 --LGLNGKVVWEATRRYVRYG--NLTPDM----GGTATTSEVTKGIISEIY 320
228917966 278 --LGLDGSIIWKAVGRYVRRG--NLTPDM----EGRATTLEVTNGIISEIY 320
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