1LAR_A 19 KFSQEYESIDPGQq---------fTWENSNLEVNK----------PKNRYANVIAYDHSRVILTSIDGv---PGSDYINA 76 human P91345 179 AISKLHQDKIKGYmp--------pNCTYTAYEANP----------DLNRYADVRCIEETRVVLKNHD-------RDYIHA 233 Caenorhabditis e... Q22852 55 KKAKISNMTREFRnnke----ykpNVTTSISEKMM----------DKNRYRHIFCGDDNRVVLKERD-----PSNDYIHA 115 Caenorhabditis e... O17889 857 WAEGIYDTIWKLD-----------VMVSTNTQANI----------SQRRHTLFLCEPKTMAKLVGFP-------DPFINA 908 Caenorhabditis e... O16728 795 QFCKSILRIANLApn--------nAIVESEKYS------------EQDRYSDVLCGMDNRILIDEDVCrrcyFKDQYINA 854 Caenorhabditis e... O01923 789 KFDAMNEKYEV-------------PGREALKSEQ-----------MKQRL-PIPLVMDTRVVLKDYGTl---FNDDYIHA 840 Caenorhabditis e... O01924 937 DFMKFFKTSYENKvan------mqSPEVSDLVKKHe----------MDLRVANPLIEKTRVILKGYKKq---FNDNFLHA 997 Caenorhabditis e... Q20324 29 GKETYQQDLDDMNld-------deKIERFIRNG------------EKNRFTNVTCFDEILDRENQE---------FFVHA 80 Caenorhabditis e... NP_507918 1151 KVWIISQDHQDADktarfynatmdQVYVTTLDKDNmtkslgylhkDKHRYDGVPCKPLTAVEVMDN------GKRVPIHA 1224 nematode NP_507932 956 DFIEGSWKIAIATqt-------klTVKDSFKYLPA----------DKHRYGNIPCTPETAVEVMVND------KRVPIHA 1012 nematode
1LAR_A 77 NYIDGY--RKQNAYIATQGPL------------------------------PETMGDFWRMVWEQRTATVVMMTRLEEK- 123 human P91345 234 SWMRMPg-KDQSTYITTQGPL------------------------------PETLSDFWHMIYQEKIAYVLMLCTLFEG- 281 Caenorhabditis e... Q22852 116 SWMVMP---DGFQFISTQGPI------------------------------KNTIADFWHMVYTEKCHVIVMLCQYIEE- 161 Caenorhabditis e... O17889 909 NVMKF----GEISWIMAQGPMdgtehleki-------------skvppkpkKSTLEKHWAVIDQYDVGIVAQLASVIES- 970 Caenorhabditis e... O16728 855 NYLELP---NGNRMILTQAPMsrtehfkpekdkkrknlyslsdeeeeisylVQTVDKFYQTIVQTGTEVVAMLCDFNEE- 930 Caenorhabditis e... O01923 841 NRVTCS---HGLQLILSQAPQeang-----------------------escESTIESYWWTAKQEKSTQLVMMCDFDEKc 894 Caenorhabditis e... O01924 998 NYVTCP---DGMRFILMQSPQceilepkpake--------kekytemtprrNSTIEKFWWMIRQEKVEQVVMTCDFLERn 1066 Caenorhabditis e... Q20324 81 NTFRT----PYGNFLISQAPN------------------------------DSTNADHLHLMWIYNVQTVVCLVLPEE-- 124 Caenorhabditis e... NP_507918 1225 NWIPTH--GHPHRFIATQGPL------------------------------DNTCEDFWAMCVYHNVDKIAMLCLNVEK- 1271 nematode NP_507932 1013 NWVPTKcpKQEHRFIATQGPM------------------------------TNTFDDFWAMIAYHECENIVMLCNFVETd 1062 nematode
1LAR_A 124 -----SRVKCDQYWParg---------teTCG--LIQVTLLDTVELA-------TYTVRTFALHKSGS---SEKRELRQF 177 human P91345 282 -----GVEKCALYYPeklg-------evvKFGkyEITLTECKEEAIA-------GTILNSLTVINTEDa-tSEPLYMNHV 341 Caenorhabditis e... Q22852 162 -----DQEKCQRYFSdts---------ekEYGdyRVKVVEKTVELWN-------PVKVTGIQVQKKNC---PTKHMVYHY 217 Caenorhabditis e... O17889 971 -----DDRKFAPYYSekvg-------ekmTFG--RYTVTTKSINTKLenftdkkSFVMYNLEYKNDQWqdkKLKKTVSVL 1036 Caenorhabditis e... O16728 931 -----GVEKCSSYFPlekd-------gkqKFH--NVNVCTTNVQHPSa------DVVLRTLVITSYLGe-kKKTHTVKHY 989 Caenorhabditis e... O01923 895 p---gKTNSCARYYPesvg-------esmKFK--NLTVECKSKIAEK-------DFETRELEVKFDGH----EPHTVTHS 951 Caenorhabditis e... O01924 1067 retglFFENCSKYYPmkvd-------telTFK--GITVKCTNMVKVD-------GIERRTLCITFGDG----VQLTVTHN 1126 Caenorhabditis e... Q20324 125 ---------AGGYFVpkegetftsfqkyqIKT--IGIFDEKQGVTVYqce-lksYKAPKKLNRRMVY-----IICCDTSV 187 Caenorhabditis e... NP_507918 1272 -----NVKKCAVYFAsdpp-------sklDIG--RFQITTQSRQLILr-----dNVIERKLLVKDTTGk--FEPKTVTHY 1330 nematode NP_507932 1063 pk-egEKEKCEKYFSpevs-------kttDFK--MFSITTVSVEKILh-----nSTEKRVLKVVDKTGk--FPTRNVEHY 1125 nematode
1LAR_A 178 QFMAWPDHGVPEYPTPILAFLRRVKACNPLD--------AGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKT-------- 241 human P91345 342 QVPWWPDQLAPEDARPMIELYKWVKKVNPKE---------KPICVHCSAGVGRTATFVGIDYATIRIMENPN-------- 404 Caenorhabditis e... Q22852 218 FYYDWHDQVAPLDPAPMIKMYKAVLNKSSSK----------PIVVHCSAGVGRTSTFVGIYLSQIMIRENSS-------- 279 Caenorhabditis e... O17889 1037 HFTAWPDHGAPKNPDYALDIIRFCESYKTS------------VLVHCSAGVGRTGTLVAIKYGIQLCTTERT-------- 1096 Caenorhabditis e... O16728 990 SYKGWIEKNAPELPREILNIFRVARNSKS-------------LVVHCSNGIGRSAAFVSWELCYHFVPVNFEicdfsvae 1056 Caenorhabditis e... O01923 952 RLVGWNPLNVQPDTLLFTSLIQKIKNS------------TTPVMVHCIDGISRSAAFASMIIGYQLVIQSLGs------- 1012 Caenorhabditis e... O01924 1127 LMSSWTYLNTQKTTISIISLIQYLNKCKG-----------APIVIHDHDGISRSATIPASIIGYQKIAETSGa------- 1188 Caenorhabditis e... Q20324 188 GSIRSPRQQTV-----IMEYMWAFEETNAIEnevaladaTTTVLVHGIAGTRRCASFVVAAVMCKQLLETGQ-------- 254 Caenorhabditis e... NP_507918 1331 QHVKWPDRDTPKTHVDTFELMELVKKS------------ENPIVVHCSAGIGRTTAFIGTEYLAREVENDPK-------- 1390 nematode NP_507932 1126 LYLNWPDKNVPEGHDDTFELMNLVKKS------------TKPIVVHCSAGIGRTMSFIGSEYLAREIEHHPD-------- 1185 nematode
1LAR_A 242 -----------------VDIYGHVTCMRSQRNY-MVQTEDQYVFIHEALLE 274 human P91345 405 -----------------IEMLDIVREMRAMRFQ-AVQSHMQFLFLYVVLME 437 Caenorhabditis elegans Q22852 280 -----------------VDMVEILKRLRTMRLG-AVQSQLQYVYLVVLMIE 312 Caenorhabditis elegans O17889 1097 -----------------TNLLSIVCPVRNCRFG-AVQSAQQLMYLIVCITK 1129 Caenorhabditis elegans O16728 1057 fvyqkmirsldttstvnLDFLSLLTELRHSRPR-AIHTPMQLAFSIMMVLD 1106 Caenorhabditis elegans O01923 1013 -----------------VKLEAVVSYIRSQRAM-AITSALELAFVDAGIVK 1045 Caenorhabditis elegans O01924 1189 -----------------FVLTDVIDYIREHRAL-AISTPGELSYIDAVIVR 1221 Caenorhabditis elegans Q20324 255 -----------------FSAMETWFEMRKRRAHtCTRKHDFFSSVYTFFAF 288 Caenorhabditis elegans NP_507918 1391 -----------------IELTEALKHLREHRWK-GVQMRSQLYWMTLGAVY 1423 nematode NP_507932 1186 -----------------TTLGKNMENMREFRSK-GIQTPQQLYWMEMGAIY 1218 nematode
Jiyao W et al.(2023). "The conserved domain database in 2023.",