5OCN


Conserved Protein Domain Family
FH_FOXN1

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cd20056: FH_FOXN1 
Click on image for an interactive view with Cn3D
Forkhead (FH) domain found in Forkhead box protein N1 (FOXN1)
FOXN1, also called winged helix transcription factor nude, acts as a transcriptional regulator which regulates the development, differentiation, and function of thymic epithelial cells (TECs), both in the prenatal and postnatal thymus. It is also an important factor in controlling the skin wound healing process, as it actively participates in re-epithelialization and is responsible for scar formation. The FH domain is a winged helix DNA-binding domain. FOX transcription factors recognize the core sequence 5'-(A/C)AA(C/T)A-3'.
Statistics
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PSSM-Id: 410830
Aligned: 6 rows
Threshold Bit Score: 185.306
Created: 18-Dec-2018
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
 
putative DNA
Conserved site includes 14 residues -Click on image for an interactive view with Cn3D
Feature 1:putative DNA binding site [nucleic acid binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1           #                 ##  #                  ## ##  #      #          ### #   
5OCN_A      3 PKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALN 82  human
O15353    270 PKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALN 349 human
AEY78524  154 PKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALN 233 African clawed frog
POI26929   36 PKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGNSSRKGCLWALN 115 Chinese bamboo-par...
ACN53914  159 PKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHFPYFKSAPDGWKNSVRHNLSLNKCFEKVENKCGGSSRKGCLWALN 238 elephant shark
AAI62597  219 PKPVYSYSILIFLALRNSKTGSLPVSEIYSFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKNGNSSRKGCLWALN 298 zebrafish
Feature 1                      
5OCN_A     83 PAKIDKMQEELQKWKRK 99  human
O15353    350 PAKIDKMQEELQKWKRK 366 human
AEY78524  234 PAKIDKMQEELQKWKRK 250 African clawed frog
POI26929  116 PAKIDKMQEELQKWKRK 132 Chinese bamboo-partridge
ACN53914  239 PAKVQKMQEELQKWKRK 255 elephant shark
AAI62597  299 PAKVEKMQEELHKWRRK 315 zebrafish

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