Conserved Protein Domain Family
Raftlin

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pfam15250: Raftlin 
Raftlin
This family of proteins plays a role in the formation and/or maintenance of lipid rafts.
Statistics
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PSSM-Id: 464590
Aligned: 14 rows
Threshold Bit Score: 714.197
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_007664372  26 MGCGLNKFEKRDEKRPGNIYSTLKRPQVETKIDVSYEYRFLEFTTLNNAELPRSSAARLSSWRDLPAQLQELYQQGFALA 105
XP_007505190   1 MGCRLNKLEKRDEKRPGNIYSTLKRPQVETKIDVAYEYRFLEFTTLTDVELPRSSAVRLSSLRDLPTQLQELYQQGFTLV 80 
XP_003463410   1 MGCGLRKLSDPEDSSPGKIFSTLKRPQVETKTDTAYEYLLLDFCL---QALPHPEVIRIHSVTDIPAQVEAYYLQGYVVG 77 
XP_343572      1 MGCGLRKLEDPDESSPGKIFSTLKRPQVETKTEFAYEYALLDFTL---QASTNPEVIKINSVLDIVAKVEDYYLKGYVVG 77 
XP_019693976   1 MGCGLRKLEDPDDSSPGKIFSTLKRPQVETKTEFAYEYVLLDFTL---QASPNPEVIKINSIPDIVTKVEDYYLKGYIVG 77 
Q6A0D4         1 MGCSLNKLEKREEKRPGNIYSTLKRPQVETKVDVTYEYCFLEFTTLTAAELPRSSATRLASLRDLPDQLLELYQQGFSLA 80  house mouse
XP_002716228   1 MGCGLNKLEKRDEKRPGNIYSTLKRPQVETKIDVAYEYRFLEFTTLSAAALPQSSAVRLASLRDLPAQLLGLYEQGFSLA 80 
XP_014440582   1 MGCGLNKLEKRSEKRPGNIYSTLKRPQVETKVDVAYEYRFLDFTTLSTAELPRSSAVRLSSLRDLPAQLLELYQQGFSLA 80 
XP_018879302   1 MGCGLNKLEKRDEKRPGNIYSTLKRPQVETKIDVSYEYRFLEFTTLSAAELPGSSAVRLASLRDLPAQLLELYQQGFSLA 80 
XP_014316607   1 MGCGLRKLDDPEDSSPGKIFSTLKRPQVETKTEVAYEYVLLDFTL---QASPNPEVIKISSIPDIVTKVDEYYRNGYVVG 77  little brown bat
XP_007664372 106 ALHPFVQPTNEREKTPQEQIFRAVLIKKTERS--QKTDYHNEGYILELECCSSLDHLAGQKIIPDFIKKIQDAASRGLKF 183
XP_007505190  81 ALHPFVQPTDEREKTPQEQIFRAVLIKKTERS--QKNDFHNDGYILELDCCSSLDHPTDQKIIPNFIKKIQDTASRGLEF 158
XP_003463410  78 ALHPILHPAGPRAPLPASHLYRAVLLRPRASPkqQAVPSTQRCQRLVIEECPVPGDAQTSDIAKELMEKVNAAARAGMRF 157
XP_343572     78 AIHPVIQPVGQRKHLPASHLYRAVLSRVKLSSk-HSAAGGQRRARLVIEECPLTCETQGNDSAKELIDKVNAAAKRGMRF 156
XP_019693976  78 AIHPVIQPVGQRKHLPASYLYRVVLLRLKLSLkhSAASSGQRRPRLVIEECPLTYETQTNDIAKELIEKINIAAKRGMKF 157
Q6A0D4        81 ALHPFVQPTRRQEKILLEHIFRAILVKKTNRS--QKAELHDEGYTLELDYCSSLEHLADQKLIPEFIKKVQEAASQGLKF 158 house mouse
XP_002716228  81 ALHPFVQPTHGLERTPLEHIFRAILIKKTDRS--QKSDVYNEGYILELDCCSSLDHLSDQKIIPEFIKKVQEAASQGLKF 158
XP_014440582  81 ALHPFVQPTHEWEKTPLQHIFRAILIKKTDRS--QKTDVPNDGYVLELDCCSSLDHLTDQKIIPEFIKKVQEAASQGLKF 158
XP_018879302  81 ALHPFVQPTHEREKTPLEHIFRAILIKKTDRS--QKTDLHNEGYVLELDCCSSLEHLPDQKLIPEFIKKIQEAASQGLKF 158
XP_014316607  78 AVHPVLQPVRQRRPLPASHLYRVVLWRLKLSPklSAAPSGQRRPRLVIEECPLMYETQANDVAKELIEKINEASKRGRRF 157 little brown bat
XP_007664372 184 VGVIPHYSSQVKTADGGVVTIPGNNSVETRDEENGSGLCEDRASLGNGNSGATHSLPLGdppalrdADTQRHPETSEEQR 263
XP_007505190 159 VGVIPQYQCPGNSAGSSPLTPTANGSGESRDEKNTLGSSEDLLPLDRETPGSADICSTP-------AGSQGDAGLWENGG 231
XP_003463410 158 IGFVPQLCPPPRCCNGTETGQGVGMEP---ADAGARPGSDDSWRSTDKRPGSGSGPVLE-------GGTGEEPHQE---- 223
XP_343572    157 VGFVPQHCSPSKHCNGASQ-DGVAESE-----LHKRQGSQDNCKSLND--GTL----WE-------SGVEEEPQPE---- 213
XP_019693976 158 VGFISQPYSPLKFCNGTNH-DEDIESA-----LPLRHTSDENCKSWNE--GTLSGQSSE-------SGIEEELHHE---- 218
Q6A0D4       159 VSVVPQYQPSVSSAGSRRLKPVANSVEDARDVKCTLGD---RSSLENDTPKAAETDAAT-------AGVNRRPETKPGST 228 house mouse
XP_002716228 159 VGVIPQYHSSPSPAGGSPTVPTAPTAHSSAGAGDAKSARGTPTSLEQESPGAPVGKEQS-------LEPGGGPAEQLSPA 231
XP_014440582 159 VGVIPQYHSPPGSPASCE-----------ADARGGRGTQEGPRSLENEDLGAPDTCDAP-------AERHQSP----GPG 216
XP_018879302 159 VGVIPQYHSSVNSAGSSAPVSTANSTEDARDAKNARGD---HASLENEKPGTGDACSAP-------AGRNQSPEPSSGPR 228
XP_014316607 158 VGLLAQHSAP--FCNGTDL-NGDGEPA-----LPGRHSCEDHGRSWSE--GPLSGQPSE-------SGAEGELHPQ---- 216 little brown bat
XP_007664372 264 EKGPAAEQLSL--PSGVGDGEEFQD---KSLSvsqdlrktpdkregdmsgmcaeplaGKLELFTIFNKPKS-QQKCRQYY 337
XP_007505190 232 ADGQRAEPLNL--STIQGNGGGSPE---KEDEssarlts------------tadtlaGKMEIFTIFNKPKSqQQRCRQYY 294
XP_003463410 224 -----GSRAQ-----GEPEGSPSPTkprKGED---------------------------PRLYAAFNAFED-DAGCWSYQ 265
XP_343572    214 -----SGQHQ-----TEGNSSLSYSnpkRGEA-------------------------PDNKVYMVFNAFEE-DSACWTYQ 257
XP_019693976 219 -----SEQCQ-----MDRDGSPSYSksrKGEE---------------------------NKLYTIFNVFDD-ESTCWTYQ 260
Q6A0D4       229 GDVPSAQQPGIpsPSAENEAGEFP------LRglqpaldrseg---dpsngpeelpsRKMEIFAFFNRPKS-QQKCRQYY 298 house mouse
XP_002716228 232 EGVNQARDAP------DDDLSEVP------AEpa----------------------pGRMEIFALFNKPQS-HRPCRQYY 276
XP_014440582 217 GEAPVAEQPSL--PSGEGDGGEFS------PGrgsttldvpdg---tpaavrgqplpGKMEILALFNKPKS-HQKYRQYY 284
XP_018879302 229 GEVPLAKQPSS--PSGEGDGGELS------SQgvsktldgles---dplevheeplsGKMEIFTLFNKPKS-HQKCRQYY 296
XP_014316607 217 -----SGPCQ-----REPHGSPRSSeatRGE---------------------------DNKLYIVFNVFDD-ESTGWTYQ 258 little brown bat
XP_007664372 338 TVSIPLRVSKNGQTVSSLDANWLEHMSDHFRKGGVLVNAVFYLGMVN-DSFHGLTDGVFIFEDVSTEESKTI-QGYDAIV 415
XP_007505190 295 TVTIPLRVSKNGRTVNSLDANWLEHMSDHFRKGGVLVNAIFYLGMVN-DSFHSLTDGVFIFEDVSPEENKSV-QGYDAIV 372
XP_003463410 266 EGALSMKVTRKGAVVSSLDADWLELTTFYYKQGFSLTDAFVCWDPPRgDPLPKSLEGFFIYEEEGSGVPGAPrRGHDAIV 345
XP_343572    258 EGILSMKVTRKGAVISTLDANWLELTTFYYKQGLSLVDSFVCWETPKgDQLPKSLEGFFIYEEEGSGVPGSNrRGNDAIV 337
XP_019693976 261 EGILSMKVTRKGSVISTLDADWLELTTFYYKQGLSLIDSFVCWETSKgDHLPKSLEGFFIYEEEGSGVPGSSrKGNDAIV 340
Q6A0D4       299 PVTIPLQVSKNGQTVSSLDASWLEHMSDHFRKGGVLVNAVFQLGMAN-DSFYGLTDGVFIFEAVSTEDNRTT-QGYDAIV 376 house mouse
XP_002716228 277 PITIPLRVSRNGQTVSSLDANWLEHMSSHFRKGGALVNAVFYLGAGT-DSLHGLTEGVFIFEAVSTEDSKTG-QGYDAIV 354
XP_014440582 285 PVTIPLRISKNGQTVSGLDANWLEHMSDHFRKGGMLVNAVFYLGMVN-DSLHGLTDGVFIFEAISTEDEKTI-QGYDAIV 362
XP_018879302 297 PVTIPLRVSKNGQTVSGLDANWLEHMSDHFRKGGMLVNAVFYLGIVN-DSLHGLTDGVFIFEAVSTEDSKTI-QGYDAIV 374
XP_014316607 259 EGILSMKVTRKGPVISTLDADWLELTTFYYKQGLSLIDSFVCWETPRgDHVPKALDGFFIYEEEGSGVPGSSrTGNDAIV 338 little brown bat
XP_007664372 416 VEQWTVLEGVEVQTDYIPLLNSLAAYGWQLTCVLPTPIVTTNREGNLATKQIVFLQRPSLPQKAKKKESKFQWRFSREDM 495
XP_007505190 373 VEQWTVLEGVEVQTDYIPLLNSLAAYGWQLTCVLPTPIVKTNREGNVATKQIVFLQRPSLPQKAKKRESKFQWRFSREDV 452
XP_003463410 346 VEQWTVIEGASVKADYGPLLHTLAEFGWLLTSVLPTPVLRQDRDGNLATKQVVFLQRPALRSSVARSLE-GEGRILRGEN 424
XP_343572    338 VEQWTVIEGCEIKTDYGPLLHTLAEFGWLLTSVLPTPILRHDSEGNLATKQVVFLQRPVTWNSAAQTPERKGGRLLRGED 417
XP_019693976 341 VEQWTVIEGCEIKTDYGPLLHTLAEFGWLLTSVLPTPILRHDSEGNLATKQVVFLQRPVMWNSAAQTPERKASRHTKGED 420
Q6A0D4       377 VEQWTVLEGTEVQTDYMPLLNSLAAYGWQLTCVLPTPILKTTREGNVSTKQIVFLQRPCLPQKTKKRESKFQWRFSRNEI 456 house mouse
XP_002716228 355 VEQWTVLEGVEVQTDYVPLLNSLAAYGWQLTCVLPTPVIKTTREGSVSTKQIVFLQRPCLPQKIKKKESKFQWRFSRDEG 434
XP_014440582 363 VEQWTVLDGAEVRTDYVPLLSSLAAYGWQLTCVLPTPVVRTTRDGSVSTKQVVFLQRPCLPQKSKKKDSKFQWRFSREEV 442
XP_018879302 375 VEQWTVLEGVEVQTDYVPLLNSLAAYGWQLTCVLPTPVVKTTSEGSVSTKQIVFLQRPCLPQKIKKKESKFQWRFSREEM 454
XP_014316607 339 VEQWTVIEGCEIKTDYAPLLHTLAEFGWLLTSVLPTPVLRHDSEGNLATKQVVFLQRPALWNSAAQTPERKASRHVKGED 418 little brown bat
XP_007664372 496 HSRQVKKS-KAKLSTREK 512
XP_007505190 453 HSRQLRKS-KSKRGAREK 469
XP_003463410 425 QNQACSGSpGSKGCTQPP 442
XP_343572    418 RNKVGSRSiGLDTSECQP 435
XP_019693976 421 RNKVTSRSiGLDTATSQP 438
Q6A0D4       457 HGRQTRKS-KGKLSASNK 473 house mouse
XP_002716228 435 HGRQLRRS-KGRLGTKDK 451
XP_014440582 443 RSRRARKS-KGQLGARDA 459
XP_018879302 455 HNRQMRKS-KGKLSARDK 471
XP_014316607 419 RHRVGSRSiGLDTATSPP 436 little brown bat
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