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PTB_Shc: Shc-like phosphotyrosine-binding (PTB) domain
Shc is a substrate for receptor tyrosine kinases, which can interact with phosphoproteins at NPXY mo...
View in Cn3D Specific ProteinProteinSuperfamilySuperfamily MembersPubMed
SH2_SHC: Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
SHC is involved in a wide variety of pathways including regulating proliferation, angiogenesis, inva...
PTB_TK_HMTK: Tyrosine-specific kinase/HM-motif TK (TM/HMTK) Phosphotyrosine-binding (PTB) PH-like fold
TK kinases catalyzes the transfer of the terminal phosphate of ATP to a specific tyrosine residue on...
PTB_tensin-related: Tensin-related Phosphotyrosine-binding (PTB) domain
Tensin plays critical roles in renal function, muscle regeneration, and cell migration. It binds to ...
PTB_Anks: Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
Both AIDA-1b (AbetaPP intracellular domain-associated protein 1b) and Odin (also known as ankyrin re...
PTB_CED-6: Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
CED6 (also known as GULP1: engulfment adaptor PTB domain containing 1) is an adaptor protein involve...
PTB_X11: X11-like Phosphotyrosine-binding (PTB) domain
The function of the neuronal protein X11 is unknown to date. X11 has a PTB domain followed by two PD...
PTB: Phosphotyrosine-binding (PTB) PH-like fold
PTB domains have a common PH-like fold and are found in various eukaryotic signaling molecules. This...
PTB_Numb: Numb Phosphotyrosine-binding (PTB) domain
Numb is a membrane associated adaptor protein which plays critical roles in cell fate determination....
PTB: Phosphotyrosine-binding domain, phosphotyrosine-interaction (PI) domain
PTB/PI domain structure similar to those of pleckstrin homology (PH) and IRS-1-like PTB domains.
SH2: Src homology 2 domains
Src homology 2 domains bind phosphotyrosine-containing polypeptides via 2 surface pockets. Specifici...
SH2_SH2D7: Src homology 2 domain found in the SH2 domain containing protein 7 (SH2D7)
SH2D7 contains a single SH2 domain. In general SH2 domains are involved in signal transduction. They...
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