Conserved Protein Domain Family
RNA1

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COG5238: RNA1 
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis]
Statistics
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PSSM-Id: 444072
Aligned: 12 rows
Threshold Bit Score: 348.318
Created: 9-Feb-2022
Updated: 24-Feb-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_083758868  129 LRNKAGAKRAIELARALQGTQVHTLNLRFNEIGAEGAIEVAKALQGTQVHTLDLVYNQIGAEGAIEV------------- 195 
AFZ23848        1 MNEQIIHCPIHDVMETASDVLEAIFPLIEHLQTNIPVTRQTTFPRGIVMPDGRLDLCKQGLGYLGFQp------------ 68  
WP_012472307  107 VKVKEVDFKYSNLKKDLTPATIPSFIFYHLMGHVRNLAQSWWPYLQGNNIHTLGLSWNHLGDQGAIVlaq---------- 176 
WP_083758875  273 FTKHLQGTQVQAVNLSFNNISDQGAEGFAKHLKETKVHTVNLSYNQISDQGAEGFAKHLQETQVHT-------------- 338 
WP_083758879  210 LQATKVHTVNLRLNQIGAQGVEELAKNLQGTSVHTVNLSENHIGDQGAEELFRYLQGTRVHTVYLS-------------- 275 
WP_014222116   41 NTAFPVGTITPDGRLDMCKQQLGIRGLELVAAPLMNNQVVKHLLLGTNAFGNTGAAAVAELVAANH-------------- 106 
WP_015179567    4 NTALHCPLPNPIESSSEVVIELKSLIDYLQTDRPIAQKIVFPRGTVMPDGRLDLCKQDLGVMGCHLV------------- 70  
WP_038540498    1 ------------------------------------------------------------------Mkyfnk-------- 6   
WP_084173760    1 ------------------------------------------------------------------Mfymfnkeqwnkll 14  
WP_083457158  306 ELDRALAHWPDGSRVAHAASLEDGPQPAHALVRRLELEQGVVDAALVRAVLGSEHTARVSSLALFSM------------- 372 
WP_051908367 1539 EWRTVNCRFPVQLGREMNKLRYLNSIQRNYHPFLKYLISLLRNEPTLTSLTLGRNEIGESCDVALG-------------- 1604
WP_051908707  589 EKTSQNTQTKSFFDRIWGRTSSSSIPSTPTQPVRSISPALLKDPKVGKYYHLLTEPHSLQRLEQIQdsheglpplvksl- 667 
WP_083758868  196 ---AKALQgtqvhkldlsnnqi-------gaegaievakalqGTQVHTLNLMGNQIGNegAIELAKAL-QGTQVHTLYLR 264 
AFZ23848       69 --iAEALAanktiaslllgtngi-----gnagaadvakliecNQHLEVVYLGCNQIAD--ISELANALtKNTSVTGLWLK 139 
WP_012472307  177 ---------------------------------------hlqGTNVHTVDISDNQIGDqgLEGFAKHL-QETNVHMVVLS 216 
WP_083758875  339 ------------------------------------------------VDLSGNQIGDqgIEEFGKHL-QGTNVHTLVLS 369 
WP_083758879  276 ----------------------------------------------------SNQIGAqgAERLAKQL-LGTSVHTIDLS 302 
WP_014222116  107 --------------------------------------------SIETVYLGCNYIEQegCKAICEAVeASPNVKSIWFK 142 
WP_015179567   71 ---TQALAnndaiaslllgtngi-----gdrgaqdvarliqrNNRLEIVYLGCNAISStgIAALAAALtQNQSITGLWLK 142 
WP_038540498    7 ------------------------------------------dnwnEIVALGSDELQL----RLKEQL---NQYSGFILQ 37  
WP_084173760   15 aqgEKGLQervetecrrytsidlkgaklqlihiqmiaeilqeNKTLTSLNLDSNNIDSegAESIAQALiKNKTLTTLHLG 94  
WP_083457158  373 ------------------------------------------------------ETQLdaIRVLADA--APAALRELQLA 396 
WP_051908367 1605 -----------------------------------------------------------------EALkINTTLTSLDLW 1619
WP_051908707  668 ------------------------------lpldmcvrlgldDHSVQLIDLSNLRLGEegLKLLWNVLsSNTTVNTLKLA 717 
WP_083758868  265 RNQIDNEGAIEV-----------------------AKALQG-AQVHTLSLSDNQIGAEGVIELA---------------- 304 
AFZ23848      140 RNPIGLSGASFI-----------------------AEMLCHnHSIRTLDLVNTNIGDQGLAIII---------------- 180 
WP_012472307  217 RSEIGDQGAEGF-----------------------AKHLQG-TRVHVVDLSMNKMGDSGAEALA---------------- 256 
WP_083758875  370 ENQIDDQGAEEF-----------------------GKHLKE-TRVHTVDLSKNYIGDQGAEGFA---------------- 409 
WP_083758879  303 GNHIGDRGAEGF-----------------------AQHLQR-TSVHTVDLSENHIGDRGAIEFA---------------- 342 
WP_014222116  143 RNPIGAESMPAI-----------------------IKMLSGnKQLRTLDLVNTCAG-EGFHLLF---------------- 182 
WP_015179567  143 RNPIGPEGADRL-----------------------AEMLRHnTSIRTLDLVNTQIGDEGLAAIL---------------- 183 
WP_038540498   38 DTSFTESQLKIL-----------------------FEVLKEnKTITSLDLSDNDLKDAEVIAIA---------------- 78  
WP_084173760   95 LNNIGDKGAKSI-----------------------IQALIKnKALTSLDISGNHIGCDGISNIA---------------- 135 
WP_083457158  397 GDAIADDASEILaasalpirvltfegattnrsvraIAAGTGlPALDHLQYHDVQVDDEGVVALAasermarlgtlrisya 476 
WP_051908367 1620 GNYIGKPGVVAL-----------------------GEALKTnTTLTSLGLGGNKISEPGVVALG---------------- 1660
WP_051908707  718 NLGMGELQAYRL-----------------------ASVVAMnKKLTQLDLSNNPLTDGGLMALG---------------- 758 
WP_083758868  305 -------NALQ---GTQVHTLYLSHnqignegaiglakalqgaqvytldlshNQIDNEGAIGL--AKALQG-TQVHKLDL 371 
AFZ23848      181 -------DALIh-qNRTVERLYLGG---------------------------NQIDCKGAQLL--ATLLRKnSAIKAILL 223 
WP_012472307  257 -------KHLQ---GTQVHTLDLSM---------------------------NKIGDQGAEAL--AKHLQG-TNLQEIDL 296 
WP_083758875  410 -------KYLK---ETQVHTVNLSG---------------------------NQIGAEGAVGL--AKNLQG-TQVHTVNL 449 
WP_083758879  343 -------KNLQ---GTSVHTVYLNHnkigaqgaielakhlqgssvqkinlshNQIGAQGAEGL--AKHLQG-TQVHTINL 409 
WP_014222116  183 -------EYMEn--NDSVERLYLSG---------------------------NYLTATTMKYV--NKMVARnKHLKSLYL 224 
WP_015179567  184 -------EVLTy-tNRTVERLYLGG---------------------------NQIQENHAALL--ANLLADnPVITGLFL 226 
WP_038540498   79 -------EVLKe--NKTITSLNLSG---------------------------NYIEEAGVIAI--AEALKGnKTITSLDL 120 
WP_084173760  136 -------DLLEn--NRTITTLDLYC---------------------------NNIGVQGAKRI--AQGLENnKTLTSLNI 177 
WP_083457158  477 qvgragaEALAstrPSRLEHLDLGL---------------------------NHVGHEGARALvaSSAL---TSLRSLHL 526 
WP_051908367 1661 -------EALKt--NTTLTSLGLEG---------------------------NKISEPGVVAL--GEALKVnTTLTSLDL 1702
WP_051908707  759 -------TSLRv--QHNLRGLDLTGv--------------------------RRVTAKGLISL--ITTLST-INLEYLIL 800 
WP_083758868  372 SHNQIDNEGAIGLAK--ALQGTQ-VHKLDLSHSK-----------IDNEGAIGLAKALQ-GTQVHTLNL----------- 425 
AFZ23848      224 NVNDLGDAGAVALAE--ALQQNHtLVELGVASNG-----------ITPQGGIRLIEAIQkHPALVNVDLgysqstrvlga 290 
WP_012472307  297 RFNQISDRGAIALAQ--HLQKTN-IHTLNLKSNK-----------IGAQGAIALVQHLK-DARIHTLDL----------- 350 
WP_083758875  450 SGNVIGAQGAEGLAK--HLQGTK-VHTLHLAGNR-----------IGAQCAEALAKHLQ-GTKVHTLHL----------- 503 
WP_083758879  410 WANQIGAQGAVEFAK--NLQGTN-VHTVYLGYNQ-----------IGAQGAEGLAKNLQ-GTSVHTVDL----------- 463 
WP_014222116  225 SVNNIGDEGVAALIP--GLAVNAtLEDLGLASCG-----------ITGKGMELLFTTLQaNSNLKSLDLgyapstkalga 291 
WP_015179567  227 NVNHLGDRGVTVLVD--GLAENKtLVDLGLASNG-----------IGVAGCNPLLAAVAtHPKLSNLDLgyspstgvlga 293 
WP_038540498  121 GYNRIREAGWIAIAE--TLRKNKtLTLLNLGYNN-----------IREAGWIAIAEALKeNKIITSLDL----------- 176 
WP_084173760  178 GLNNIGDEGAKNIAQ--GLENNKiLTSLNINYNN-----------IGNEGAKSIAQALEkNYTLTFLDL----------- 233 
WP_083457158  527 SENRLGGPGVRALAEhcSLER---LAELSLSYNQdsnrlldpdsmVGTDGVRALAAARW-LRTVERLEL----------- 591 
WP_051908367 1703 GDNEIGDPGAVALGE--GLKTNTtLTSLDLMGNK-----------VSDSGAVALGEALKtNTTLTSLDL----------- 1758
WP_051908707  801 NQIPLTFESALALQN--LLEHSSpLRVLCLAQTG-----------LSDVEAKFLAKALKeNRTLEILKL----------- 856 
WP_083758868  426 MINEIGNEGAIGLAKALQG-TQVHTLDLMANAIGNEGAIGLAKALQGTQ--VHTLGLSAnqignATKQLLVEQYPH---- 498 
AFZ23848      291 IANSLGDAGAEAIANLLVNnQTLRKINLRRNGITEQGKLSLIAGLQHNRt-IRQLILDG-----KQHSQITALIQRnfnl 364 
WP_012472307  351 CENKIKDAGVIALAQYIKG-TSVHTINLSKNKISVLGAMELAKHLQETN--VHTLNLGYnliraGqlvkhlqgtrvhtln 427 
WP_083758875  504 SMNQIGAQGAEGFAKHLQG-TQVHTVDLSYNQIGDQGAEALAKHLqgtqmhtvilagnhigaqgaeefakhlqgtqvytv 582 
WP_083758879  464 TSNQIGDQGAEGLAKYLQG-TQVHTVNLSSNNIGAQGAEELAKSLQGTS--VHTVDLRWndigaDIQRLLVEQYPH---- 536 
WP_014222116  292 KANELSVASAALLIEFIEGrPNLINLNLGKMNLPEVERNKLIDEMN----------------------------KRngsl 343 
WP_015179567  294 QPNQIGDIGASAIAHSIARnQTLLKLNLCRNGIGNLGKKALIAALEINQk-LRYLILDG-----QPDRRIEVLLDRnrml 367 
WP_038540498  177 SDDYITDKGAIELIKLLESnKSILEINLRKRTISPDKFEEVNDLILKNRvif---------------------------- 228 
WP_084173760  234 YFNPIDDEGVKSIAQAIAEnSSLTFLNLGANNIHDEGAESIIQALKTNRt-LTALKLDSnhigyEEQAKIEQALERnihv 312 
WP_083457158  592 AGNAIGDEGMDALCTSPNL-GGLRELDVADNQLGSRGVAALLASSVIDQ--LKKLRIELnelgdDARDALFDACEArgia 668 
WP_051908367 1759 MGNKVSDSGAVALGEALKTnTTLTSLNLRGNWIYKSGVVALGEALKVNTt-LTSLGLGDgiyesqwfsedfirllrnept 1837
WP_051908707  857 EDNRLSDHSAKVLAQYLVNhPTLRELHLGGNKLTKKGAQYLIDMLQTGKirLARLTFSPgllteEMEQRLNQLLDRh--- 933 
WP_083758868  499 -------------------IKWKF 503 
AFZ23848      365 elekd-----laiardvalIKSVY 383 
WP_012472307  428 lngnnidgqgvialtqylegtnvq 451 
WP_083758875  583 nlsenhidgqgaegfakhlkgtnv 606 
WP_083758879  537 -------------------IKWSF 541 
WP_014222116  344 emrgyqsertypahadskaIKSVY 367 
WP_015179567  368 nlgee-----lhqprsvslIQSVY 386 
WP_038540498  229 ----------------cneIERLY 236 
WP_084173760  313 aslf-------hgkgiigvLKKML 329 
WP_083457158  669 lva--------------------- 671 
WP_051908367 1838 ltsldlsgdgigdsggvalgealk 1861
WP_051908707      ------------------------     
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