Conserved Protein Domain Family
SRP9-21

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pfam05486: SRP9-21 
Signal recognition particle 9 kDa protein (SRP9)
This family consists of several eukaryotic SRP9 proteins. SRP9 together with the Alu-homologous region of 7SL RNA and SRP14 comprise the "Alu domain" of SRP, which mediates pausing of synthesis of ribosome associated nascent polypeptides that have been engaged by the targeting domain of SRP. This family also contains the homologous fungal SRP21.
Statistics
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PSSM-Id: 428490
Aligned: 95 rows
Threshold Bit Score: 62.6072
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CCE32263       4 FKTSQEWLEKSSLLIEARPKTTRVTTRYSIKpapAGKQPKSTTTttasptttatttttttttttitpsstpsdaaaraas 83 
CCK68293       3 IKPIDTFITNGVRLFEVNPSQSAFSITYKPP---VVKSDKGAEKkv---------------------------------- 45 
CCF57953       3 VKPIDTFIVNGIRLFEINPSQSTISITYNPK---NGKKE----------------------------------------- 38 
Q6FM21         3 VKPIDTFIENSVKLFEANPSGSSITISYHGGa------------------------------------------------ 34  [Candida] glabrata
XP_003672574   3 VKPIDTFITSSVKLFEVNPSQTTFTISYRGP---SDTDNNK--------------------------------------- 40 
CCC66997       3 VKPIDTFITSSVKLFEVNPSQTVISLTYKTP---TEKK------------------------------------------ 37 
XP_003686568   3 IKPVDLFISNSVKLFEVNPSQTTISLTYKFL---EKKKN----------------------------------------- 38 
XP_001645608   3 IKPIDSYISNSVKLFEVNPSQTVFSLTYKFP---KNSNN----------------------------------------- 38 
XP_002498115   3 VKPIDSFISQSVGLFEANPSQTTFAISYKNR---LPAQL----------------------------------------- 38 
CCE89557       3 VKPIDTFITNSVQLFEANPSQTIFSISYKCK---SKSTQ----------------------------------------- 38 
CCE32263      84 tpkpPRGSIVLTTYDPVTGVNLKYRTTKAAEVSRLVqAALGRLGRCM 130
CCK68293      46 --skKCTKVAFRFNNAHLATNYSFDTNKSKDVSRLL-NSLGPRGVSI 89 
CCF57953      39 ----KSSNVSFKIHNPHLNTNYKFRTNKSKDVSKLL-NSLGPRGVTi 80 
Q6FM21        35 ----KADPVVFRTHNPHLSTTYKYQTKMNKEVSRVL-NALGPRGVSM 76  [Candida] glabrata
XP_003672574  41 ----KKTSVSFRSHNAHLGVSYKFNTNKSKDVSRLL-NAIGPRGVSI 82 
CCC66997      38 ----RQSDVIFKTHNPHLGTSYKFSTNKSKDVSRLL-NAVGPRGVSV 79 
XP_003686568  39 ------STVTFKTNNPHQSTNYKFQTNKSKDVSRLL-SAMGPKGVTI 78 
XP_001645608  39 ------CTVKFNTHNSHLSSNYNFKTCKSKDVSRLL-SAIGPRGVTV 78 
XP_002498115  39 ------PQVSFKTHNPHLNCHYKFQTCKSKDVSRLL-SALGPRGVTV 78 
CCE89557      39 ----KKPVVSFKTHNSHLSNHYKFKTNKSKDVSRLL-SALGPRGVSI 80 
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