Conserved Protein Domain Family
Mplasa_alph_rch

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TIGR04523: Mplasa_alph_rch 
helix-rich Mycoplasma protein
Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Statistics
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PSSM-Id: 275316
Aligned: 14 rows
Threshold Bit Score: 431.752
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jcvi:MMCAP2_0894   1 MKKLTSLLAVISVITATGLGYVGYKNI-----AVSNNTKEQSMLNQIKSIKKELKTKELELKNIQKILNDSENKKNELTN 75  Mycoplasma ...
WP_008362953       1 MKKLTSLLAVVSVFTATGLGYVSYKNI-----ANSNNAKEQNMLNKIKSIQKDLKNRQLELKNIQKTLTDKENRKHYLEN 75  Mycoplasma ...
jcvi:MMCAP2_0896   1 MKKLTSLLAAISVFTATGLGYVGYKNI-----TNFKDTEQNNVINKIKTIKNDLENSQQELKNLEKLLKEKENKKTNLNT 75  Mycoplasma ...
WP_008362957       1 MKKLPILLATISVFTSSGFAYVTLKNV-----AVKRDSRESEMSKELDTLKNQLKQKQKIAEDIQNNLILKKEQINAFNN 75  Mycoplasma ...
jcvi:MMCAP2_0895   1 MKKLIVLLTAISVFSAAGISYVGYKNLsndttINNQEHEFKQLEEKLRTLQNEILNSEAKIKDLD---TKDAEIIKNSNE 77  Mycoplasma ...
jcvi:MMCAP2_0897   1 MKRLILLLTAISVPTASGISYVRYKNLstnntINKQDNELRRLEKELEQIKYEIKTREDKIKALD---LKDAKDIQNINT 77  Mycoplasma ...
WP_008362955       1 MKKLIVLLTAISVSVASGFSYVAYKNLsnnsaGSRQENEFKQLEKELIKIQSEIKNKENEIKTLD---IKDAETIKNSNT 77  Mycoplasma ...
WP_011387686       1 MKRLTSLIAAISVFTATGLGYVGYKNI-----ATSNNTKEQKMLNKIQSIRNDLKNREQELRNLEKYLNEKESRKKYLND 75  Mycoplasma ...
WP_013729992       1 MKKLTSLLAAISVLTASGIGYVSYKNV-----TNSNSIKEQNMLNKIKSIQKDLKNRELKLKSIEKTLIDKENKKNQLND 75  Mycoplasma ...
WP_013729993       1 MKKLIVLLTAISVFSAAGISYVGYKNLsndttINNQEHEFKQLEEKLKTLQNEILNSEAKIKDLD---TKDAEIIKNSNE 77  Mycoplasma ...
jcvi:MMCAP2_0894  76 QINNLDANITSLNDKGKTNKNRLNKLDADLVKINSEIKLDNQNISLKENEIKKLEEQIKENKRLLKTILNEFFKKEKELE 155 Mycoplasma ...
WP_008362953      76 QIKELETNINDLDGKEKISKDKINKLNADLVEINNEINVDKQNISTKETEIKNVEKKIKDNKKLLTKVLDELFKKEKELD 155 Mycoplasma ...
jcvi:MMCAP2_0896  76 EIKILETSINNLNNKTKTNKTKLDKLNADLLNVNNQLDIDKQNISKKEVQISSLEKQIKETKKNIDKVATEILNKHKQIK 155 Mycoplasma ...
WP_008362957      76 EIKGLETQASNLNDQLVKNKKQLETLDSSSKKINEELKNDNDQINANKDKYNSSKKELDKVKKEIIDDLVRVTNDSNLVD 155 Mycoplasma ...
jcvi:MMCAP2_0895  78 KIKILKQLESDITSKLTQENNKINELIKNLNISISESKIKKEQKIKLEQELAKLKREKLKNDANHTFFNGEIRKLQDKLV 157 Mycoplasma ...
jcvi:MMCAP2_0897  78 KIELLKQQEKQIKDKLTKESNVINKLNEDIRLFKAEVKTKKEQKNKLEVEFNKLKEQKNQTNKKQFLINTRISWLKDQLN 157 Mycoplasma ...
WP_008362955      78 TIEILRQREKSIKNKIDKENDKINSLNKDLSVLVSEEKSKREQKDKLEKELAKLEKSKEKDNKNQKFFNEEIKRLEADLI 157 Mycoplasma ...
WP_011387686      76 QIKTLEANISDLNNKDKISKSKIDKLNSDLLKLNDELNLDKQNILTKESEINKLEKQIREIKETLNKTSTEILKKEQELK 155 Mycoplasma ...
WP_013729992      76 QIKNLESYINDLNSKEKISKDNIDKLNADLIKINKEIDDDKKIISIKETEIKSAEQQAKENKKNIIEILNELFKKEKELE 155 Mycoplasma ...
WP_013729993      78 KIKILKQQEKTIKDKINNENKKIDDLDNELSFFASEIKTKKEQKNKLEFELNKLKKEKQKNDEHEAFFKNEIKKLETNLN 157 Mycoplasma ...
jcvi:MMCAP2_0894 156 DLFAKNEKINKEKSELENVKKSFSDEIHKLESIVQKSNWKYLILNQKLSDIKKYNERINLLNSQINNLKEQSKILKTQFD 235 Mycoplasma ...
WP_008362953     156 DISNKNRETNKQKRELENYKNIYISEIANIENTIKDINSKRLALELKLLNIDSLNKKNKSLSSKITELKNQNQNLEDNLI 235 Mycoplasma ...
jcvi:MMCAP2_0896 156 ELSNKNKDTTKLKEQLENYKTTFINELSNIKSALNKIRNKRFILELRLSNIKKYEEKNKTLVSQTNDLKKQNTQLTNEVE 235 Mycoplasma ...
WP_008362957     156 EINSKINDLRKQKTELELDKDLLKEQILDIENNLTNTRKQHSKLLTTLFTLVKLDKKNKTLEKQITEFKSKNTQLTDNIT 235 Mycoplasma ...
jcvi:MMCAP2_0895 158 LSNTKLDELKERIKSYESELIKLETDKNNKQKNIDKVKNELAKKQHLILVLKLKIQEYDQLLKDYSNLEEQFNSLKKSVN 237 Mycoplasma ...
jcvi:MMCAP2_0897 158 SSNVDYDNLKKLIETYKNDLLKLEKDKLDKLKNNSDLNKQLTRSKYLLSVLQAKIQKQTELQTKLVELEEQKNNLQKTAK 237 Mycoplasma ...
WP_008362955     158 YLNSDYSRLKRQIQDYETELNTLKKDKQNKQEKIDNIRHQLRQKHYFLSLLETKKQLHKKLQDEISHLEQKQSSLNESVE 237 Mycoplasma ...
WP_011387686     156 SLTNKNQDINKEKLELENQKKLFSDQISEIKTTINQIHSKRLALELKLLNIQKYSEKNKLLTSQINELKAQNNKLESQKD 235 Mycoplasma ...
WP_013729992     156 VISHKDREINKQKLELENSKNIYLDEISKIESIIKNINSKRFALELKLSNIQSYNQKNRLLNLQINDLIRTNINLKNNIS 235 Mycoplasma ...
WP_013729993     158 YLNSNYSNLEKQIENSKKELTILENQKQNKQKNMDDIKHQLRKKNYLLSILEAKIQKHNELKIKVSDLEKQRSVLSKILE 237 Mycoplasma ...
jcvi:MMCAP2_0894 236 LEKSKLSDIEAKISFAESQLINVKSEQERIKNQLQQKQNEIDKNNKLISNLEAQLQQLKSELENLNSQKSENWNKDLKNQ 315 Mycoplasma ...
WP_008362953     236 SENQKITEIQTQISNTEKQISTIKSEHQKINTQLQEKQKEIDTQNIKINDLKNQVQQLESKLKDLKNQKDQDWTKEFKKQ 315 Mycoplasma ...
jcvi:MMCAP2_0896 236 TLNQQLNKTNSELESITQKINDTKQEQEKIKKQLIDKQKQITQNNKKIDQLTKLVKEYENQLEILKNEKNQVWHKELKDE 315 Mycoplasma ...
WP_008362957     236 KLNNDFNALKTEISTTQTNITNAKNQQIEVVEQLSAKQKEVEQANALLIEKTNQLNTLNTELSVLKNQKQQGWNSKLHEQ 315 Mycoplasma ...
jcvi:MMCAP2_0895 238 EKQKEIQEKTEILQRTHEQLQQLSNSNDNDKKELKNKISKLEQTEEKISNLNNQINQVKSEISDLNKKKESDLMN-VKSE 316 Mycoplasma ...
jcvi:MMCAP2_0897 238 EKQQEINNKQAILNNNKDQLKQLIESSTNNKNQLDNKTLELNQTSKKIKELEDQLNKLKSEISDLNKQKEEDLLK-VKTN 316 Mycoplasma ...
WP_008362955     238 KKQEEIQQKTNALQSAKNQLIQLSDLKDNTKRKLERKILESEESKQKIITLEERLQNINAEILALEQVKENEISK-IKSD 316 Mycoplasma ...
WP_011387686     236 LENKKFSELQTKILEVQKQLEDTKVQQPKIKTQLEEKESQIKQNNTKIDNLTKEFKQLESQIQNLNNQKKQGWNKELKEQ 315 Mycoplasma ...
WP_013729992     236 LKKDRLVEVKTQINNVETQINVIKSEQQKINDQLQEKQIEINKHNTTISDLEKQISELQIELNDLNNQKQQDWTKDLKEE 315 Mycoplasma ...
WP_013729993     238 QNQQEIEQKTNVLKNTQEQLNQLSNSNTDALKRLENKTLELEQAKRKNINLENGLKEIKVKILTLKQEKEEETLK-VKSD 316 Mycoplasma ...
jcvi:MMCAP2_0894 316 LKEKQDQLTQIKSEITKNEQAINRLKEQVTSLESELETSRNNNLEKQNELKEKQKKIENINKENNSKKQESLQLESQINI 395 Mycoplasma ...
WP_008362953     316 LENQKEKIRETKSEIANNEQRISKLNEEIASLEEEVNGLETDNLKKQNQITEKQRQIKDIQRDNESNKLKINNLESEISD 395 Mycoplasma ...
jcvi:MMCAP2_0896 316 LKSQENKLSEVDSQINKNNQLISELNRDISKLKQELSNLENDNSTKQQELNEKLNKIQTIKNENQSYFKQKYDLEIKTRS 395 Mycoplasma ...
WP_008362957     316 LTQQKNKKVEIENQISNNNQKITDLNNQINDLRTELNNSNSTNVSKRRELQQKEDLIRSIKSENDSKKQELQNLKSSISD 395 Mycoplasma ...
jcvi:MMCAP2_0895 317 ISDIDKQLEIANTKLSQSNESISQLKEVIKQLKKDKSHSTLENQKLDRQIEEKNTAIQKLEKEQQQYLTNIEKLNTQKSN 396 Mycoplasma ...
jcvi:MMCAP2_0897 317 IQNNKNQLEVLQNQLDQINKKIDELKQSIEQIKKSIKDKQTENQELDEQLKEKNIELEKLKKEKQKYLNSIEKLTKKSND 396 Mycoplasma ...
WP_008362955     317 IKKVERELEQSQNQLRESIKNINQLNDTINQIKNTRTNKESEKEEINRQLEEKTSELEKEERQKQEYLDTIQSLINQKEN 396 Mycoplasma ...
WP_011387686     316 LKSKQEKLTTIKSKISENEKAISEFTEQISILEKEVKDLENDNSSKQKELNEKHQQLELVKKENDSKKQEIKNLESQINS 395 Mycoplasma ...
WP_013729992     316 LKSQQNKVQQIRLDISKNEEIINSLNQKISNLEKEIDNLETDNSERKEELTQKQQEVETIKRENSSKNEEITQLKSEIKA 395 Mycoplasma ...
WP_013729993     317 IENIKKQIDNLQNQLVQSTKIINQLENTIQKIEKTRTNKESENKKINKQLEEKKSELIKLKKENQGLSDSIKNLKTQKNK 396 Mycoplasma ...
jcvi:MMCAP2_0894 396 LNSKIQEQEKVSQELEKKIKKVEKNKNIIEEEIEKLRKKITEEQKTIKNLKDQDYVLELEYDKTDSYKESLKIQTKVFEI 475 Mycoplasma ...
WP_008362953     396 LKLKIQNQEQTKQNLDGNIQSLESNKQQIEEEIQNLKSTIEKNKNTIRDLEEKDYVLELQYEELDAKRDVLNTQIKAYKY 475 Mycoplasma ...
jcvi:MMCAP2_0896 396 LKSKIRHQEQIAKKLDIKIKGIQTNKSLLEKEIDNLKQTTTKNKETLKDLIKEDNQLENKFNKLNILRDELKTKIEIFKL 475 Mycoplasma ...
WP_008362957     396 LESQIQKQKELSAELDNRIHQKQQEKRLKEQEIQELRNTNEQNKQEIERLKSKESELETTINELGNTREQLKKQIDTISA 475 Mycoplasma ...
jcvi:MMCAP2_0895 397 LEQKLEKIKKENELKEQQLENQQLEYEKLSREYTRLLAFRIVLNSEISDLTNEIAAKKIILKNHKKFIEKEEQYLESLTK 476 Mycoplasma ...
jcvi:MMCAP2_0897 397 LEQTFKDITNSNKQKEQQIKTLEQEYNKLLKQHKLLLALRIDQNSQISSLTEDITVKKLIITNLEKTTSIQQKEVDKLSG 476 Mycoplasma ...
WP_008362955     397 LNNKFQNYDKENKQKQERIEVLKQEHNELQKQQELLSEQIISQNKEISDLTNQIAAKKIVIKNLKRSTKHQEEKIEALTR 476 Mycoplasma ...
WP_011387686     396 LELKIKKQEVDTQIFDTEIEEAQESKLVIEKEIEKLKSEIAKNKDTIKDLKEQDYVFELKYEKLDSLRDDLKTQLKVFEI 475 Mycoplasma ...
WP_013729992     396 LETKIQQQQEVEQNIDSNIKNLESQKQLIEKEIQNLKSTVLKNKATIKSLEEKDHVLELKYEELDFKRDAFNTQLKVYEL 475 Mycoplasma ...
WP_013729993     397 LEQELQINDEKNKQKQEQLRIFKKENDELLKQQKDLSEQIVFQNNEISDLTNEIAAKKIAIKNLERSTKYQEEKIKLLSG 476 Mycoplasma ...
jcvi:MMCAP2_0894 476 EIRKIEHKQKEIKKELKTKEQEHKTLISETKDLSQRTKDLERQVSLSKQRIEQLNLEKTKKETELKDLESKIDKMEFNLT 555 Mycoplasma ...
WP_008362953     476 SINNLELKLEKNKKEIKSKETEINGLTEVTKELDGKVKELNQKISSSESTIQELESRKTQKENELRDLERKIEEKKFVLT 555 Mycoplasma ...
jcvi:MMCAP2_0896 476 SIKKAKSDLEWTNKQLVEKEKQIKNITNEISQLKQQQKDLVKEISFLTNSINKLESEKNTKETKLKQLETEINNIESGLT 555 Mycoplasma ...
WP_008362957     476 SINENDTSLDQLVQEFDKDVKELDELTKHNKQLKENVDYLKQKIASIKSNVDKLKALKAQKESKLDELDKKLNSLDFENK 555 Mycoplasma ...
jcvi:MMCAP2_0895 477 KYNSIKQDLKIKQQQFEQKKSELLMLKAQKTESENKISNLTKEQSEFIEKQKQLSTEIKEINNKISSKKDEFLKDNDDLK 556 Mycoplasma ...
jcvi:MMCAP2_0897 477 EYNIIKKNLQDKSKELKEKTSEFLKLNNEKTNLEKQVKDFTEKQKELLEKQKKLSSEIKQIESKTSEIKNKLLKDDQGLK 556 Mycoplasma ...
WP_008362955     477 EYKTVKNEWEDKQRELANKNSQLEKLKQQKSELEEKFAELNSRQDELLKKERELTNKISEIDRQISSKKDEVIKDNTELK 556 Mycoplasma ...
WP_011387686     476 SIKKTKQNLEKTKQELKSKEQEIKKFNDEVKKIDQENKELNKQISLLKNNVEKLESEKLEKEQEFKQLESKINEMKSNLT 555 Mycoplasma ...
WP_013729992     476 SINKLQSNLEKNKTEIKLNEQKIKSLTEETKDLNEKVKDLEPNISSFKSTIQNLEIEKSKKEKELKDLEDNINEMKFVLT 555 Mycoplasma ...
WP_013729993     477 EYENNKRNLKNQEKNLKDQTDMLLMLNKQKIDLEGTLVTLTKEKDQLIVNEEKLNNEISEINKKISDKKDELIKDDTTLK 556 Mycoplasma ...
jcvi:MMCAP2_0894 556 KEGLEKEIQNKQKEIEQLKEDKESLLATQSEIEKLLQDYESDKKDIKKQIAANMITQGSLEEEIEKTEKENRKLLSEIDG 635 Mycoplasma ...
WP_008362953     556 KDNLEKEIQEKQNQIVQLKQDYKSLIAKQEEADNLIKQYEAEKKEIGKELAKKIVLLSELENNLDNSEKEKKKLNNKIND 635 Mycoplasma ...
jcvi:MMCAP2_0896 556 KEKLEIELNEKQKEIEQLEQDQKSLLVNQEEADKLLKEYEDQKKEINKGLSKKTYTITTLEKQITEIQKENSDLDTEIRN 635 Mycoplasma ...
WP_008362957     556 FSQLEKQKRKYDEEIVKLHNEQTALKNKQRELEEKIAELESKNNALTSKQAEKEQLADQLEKQASTIKEQNRKIEAQIMK 635 Mycoplasma ...
jcvi:MMCAP2_0895 557 R--IKEVVDSSNKTIEELKHTNENIERANTEKQEEIDKKADKILDLIKEVEMYETKISQLTRDLNLAEKEHERLSTIKAN 634 Mycoplasma ...
jcvi:MMCAP2_0897 557 N--IKEVIDGLNQKISELKHTNDNLTKSNDKKYDIADQKAAEIVDLIKEIETKESKISELDKEIRIVRKKHKELSIIESN 634 Mycoplasma ...
WP_008362955     557 R--LKDVVDSINQNLSELKHTNDELEKSNKQKQELADKKSQEVQDVIKQIENYGEKVAKKTDELEKAKKEYEKLSLMKKN 634 Mycoplasma ...
WP_011387686     556 KEELEKEIQQKQKEIEQLKENYNSLLASQTEFDQLVKEYEFERKKIRSELAKKIILSSSIEDEIESVNKENKEIESQIKT 635 Mycoplasma ...
WP_013729992     556 KDNLEKEISEKQQEIEQLKLNYKSLLSNQEQVDILIKQYEAEKKEIKKQLTIKIVLLSELEEKFEKAEKENRKLNSELKN 635 Mycoplasma ...
WP_013729993     557 --NLKTVIDGIDQNLSEWKNNTSKLKKSNDQKQELADKKSKEILTIIEEIETYGMKVWNVSQKLEETKKEYEKLSLIKMN 634 Mycoplasma ...
jcvi:MMCAP2_0894 636 ILSKKNILKQEVEHMQDTIDEIRNKEPiNIDKEINTSVDLVNEIIVTMGKW---NKALAHIKPNITNKIRYGLEPSLEEH 712 Mycoplasma ...
WP_008362953     636 LKEKKNILVQEAIAIYDTIYEIRNKKPtNIETSAKDAITKVNDIIVAMKDWe--KEGWLHEKPKITRRIKNIDLPLLVIH 713 Mycoplasma ...
jcvi:MMCAP2_0896 636 IKNMKSSLVQEVKFIQTTIDNIINKKPdNADKKIKDSISKIDDVINLMETWk--QEKWLHLKPYITEHLKNIDLPTLEEH 713 Mycoplasma ...
WP_008362957     636 IQNSKDYLKEQVEQIKKQVDPTVVKTN-DIIENIKTSVIKVVDINKLMLDWk--NEKSNSRKKAITNKIRDNDLEKLKQA 712 Mycoplasma ...
jcvi:MMCAP2_0895 635 IESASNKIIEYIQQIRFGFKTTKESLA-EIIKKDQELKEDLSSFSELVKKWlvpEELSVRYNEYIKKMTPIQE--KINKN 711 Mycoplasma ...
jcvi:MMCAP2_0897 635 LELSSEKINQIIKQVKEELKKAKNTWN-EMVFKNTDIKKTIDEFIQTTKKWldpKELSIHYSKYVSEMTRIKW--QIADK 711 Mycoplasma ...
WP_008362955     635 LESSLKKINELLKLIKEQFDKVRAIWP-EIITKNKELKTIIDEFIKITRDWlipSELSIHYNKYIKPMMDTKN--KIDEK 711 Mycoplasma ...
WP_011387686     636 VLKKKHTLKQEAEAIYNTIDEIRNKKPyNIDQKTKDSISKIGDIIEAMKTWn--SESLLHIKPRITDRIRKNDLPLLEDH 713 Mycoplasma ...
WP_013729992     636 IKEKKNNLIQEASAIHDTIYEIRNKKPnNIENAAQNSLTKINDIIELMKIWd--KEGLLHVKPEITNQIRHTDLPLLEDY 713 Mycoplasma ...
WP_013729993     635 LNSSSNKINELLHSIKEEFNKIRAIWP-ETITKNKELKVIIDEFIEITQKWvdpSELSVRYKKYIKPMTEIKK--RADDK 711 Mycoplasma ...
jcvi:MMCAP2_0894 713 FKHIESELKIITELDEALNSFIDNFNDKFDDNY 745 Mycoplasma mycoides subsp. capri str. GM12
WP_008362953     714 SEKIEEELKVIDYFEDVLVDAMSKFDKKYNENT 746 Mycoplasma sp. G5847
jcvi:MMCAP2_0896 714 YKYVEKEIKIQEEFSNILEQLIDIFNKKYDDDI 746 Mycoplasma mycoides subsp. capri str. GM12
WP_008362957     713 YDKIVGELGEVQKFGKQLETIVNDFNKKFDDKF 745 Mycoplasma sp. G5847
jcvi:MMCAP2_0895 712 HKEIKELNSKLDQYKKEIKDNIKNLEKIIYDAI 744 Mycoplasma mycoides subsp. capri str. GM12
jcvi:MMCAP2_0897 712 YKNIQRINAKFLDHKKNLEINISNLEKIVDYAL 744 Mycoplasma mycoides subsp. capri str. GM12
WP_008362955     712 YLEVLDIYSKLDGYAKELKNHTNNLNKAVDDAL 744 Mycoplasma sp. G5847
WP_011387686     714 FEHVKKELEVLKEFSDILENFIKKFNQKYNDKF 746 Mycoplasma capricolum
WP_013729992     714 SKRIEEELRVLDYFEDVLVNIMSKFDKKYDENT 746 Mycoplasma mycoides
WP_013729993     712 YLEISGLYSRLDQCVKDLDSYTKKINKTIDDAL 744 Mycoplasma mycoides
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