Conserved Protein Domain Family
IPP-2

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pfam04979: IPP-2 
Protein phosphatase inhibitor 2 (IPP-2)
Protein phosphotase inhibitor 2 (IPP-2) is a phosphoprotein conserved among all eukaryotes, and it appears in both the nucleus and cytoplasm of tissue culture cells.
Statistics
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PSSM-Id: 461504
Aligned: 95 rows
Threshold Bit Score: 55.532
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_013960147  86 LKWDEAN---LYLTE--QERTSTMKITEPKTPY-AKHYDPTedpsddeeaaqgsldgaasGRKNQRAGAedDIPGLSL-G 158
XP_002902930  28 VTWDEETi----ALHnlDRG-TRMKIDEPNTPY-HYYAegdgv------------gavspARSLSGREAqpPIQWEEL-Q 88 
2_pfamImport   1 VTWDEETi----ALHdmDRG-TRMKIEEPNTPY-HYYVesdqv------------gavspARSFSGq---pSMQWEEL-Q 58 
KAH7468618    28 VTWDEETi----ARHdlDRG-TRMKIDEPNTPY-HYYAegddv------------ggvspARSLSGKEAqpPIQWDEL-Q 88 
XP_002293304  56 LTWDEHAi----EEHdlLRG-TRMKIDEPNTPY-THYDhhsedeas------tssgqhprSPDENSKHLppAIAWNAL-E 122
Q580S8         7 VMWDEKNl--EDNEEyrRTHPVTMHITEPKTPFqypedeedfee------alernddgggDEVENGGTWdpKVNELARqV 78  Trypanosoma brucei
XP_001566366   7 VEWDEQNl--EENAEyqRQHPVTMHITEPKTPFsyadg------------------ddleAEEEALLKWdpAVNAKVKeI 66 
XP_001466539   7 VEWDEKNl--EANAEyqRQHPVTMHITEPKTPYsyadg------------------ddleAEEEGLLKWdpAVNAKVKeI 66 
XP_002865901   9 VQWDEANiveIESNKpvRQ-----KITEPKTPY-HPMID-Ddgslsprgr------------------sfdecvddMQrA 63 
XP_006365232   3 VKWDEEKleeIEANKpvRM-----KITEPKTPYhHPKIDDDdnf-----------------------------eeyGNrS 48 
XP_013960147 159 EPEe----EIPERPAPATRSssEKTvhvdkes--------vtpsaeEEVVGLSPeE-RE-KHRKFEEARKKHY-E-MKSV 222
XP_002902930  89 SKLq----GVKDNKKSewdsdees---------------ssstsgaQQFAARDAeGkKIqKDPDFSEKRKMHY-NeFERV 148
2_pfamImport  59 AKLr----DVENTTQDesaesdee--------------ssssalegLNFAARDSeGkKIhKDPSFADKRKNHY-NeFERV 119
KAH7468618    89 SKLq----DVKDGKKSewdnsd------------------nessegLSFAARDEeGkKIdKDPHFAEKRKMHY-NeFERV 145
XP_002293304 123 SKLq----AVADKRDACPLSpaPSRdsnm-------------sdseGEEAVKRRkKkEMeHKKEFETHRKKHY-NeAEAM 184
Q580S8        79 Reefrkeapvvv------------------------apvapsgrpmLSDEVVSGeAlEKqRAAEFKTMRKAVYaDeGARV 134 Trypanosoma brucei
XP_001566366  67 K-----------------------EqvtgdfsdrpiapttkagrpmLAEGTVTGeLaKQqHQKEFRKMRKAVYaDeGAMF 123
XP_001466539  67 K-----------------------EqiagdfsdrpvapiaksgrpmLAEGTSTGeLaQQqHRKEFRKMRKAVYaDeGAMF 123
XP_002865901  64 EELrivlnDAAASSSRNSSQgsGGGgwsssde----------eeadpmEQDEEGsGsG--KNERFNAHRKAHY-DeFRKV 130
XP_006365232  49 DDVd---dDMASCSSKNISDdpRKNgddddddn-----dvvvmnhaDVDADEDSdEsER-K-RNFIEHRRGHY-DeYKRI 117
XP_013960147 223 AHILGHPEAMPDDED 237
XP_002902930 149 RAWKMQHADEDDDED 163
2_pfamImport 120 RNWKMQHGEEDDGND 134
KAH7468618   146 RAWKMQHAAEDEEEE 160
XP_002293304 185 KRWKMEHQNDDDEDD 199
Q580S8       135 KALLGKGNTFDDDGD 149 Trypanosoma brucei
XP_001566366 124 KKALTQNGKDEDD-E 137
XP_001466539 124 KRALAHECKDEDDE- 137
XP_002865901 131 KELRSSGSFYEEEEE 145
XP_006365232 118 KELQRNGSLLQEFDD 132
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