Conserved Protein Domain Family
DUF4517

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pfam15006: DUF4517 
Domain of unknown function (DUF4517)
The function of this protein remains unknown. This family of proteins is found in eukaryotes and are typically between 160 and 182 amino acids in length.
Statistics
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PSSM-Id: 464438
Aligned: 17 rows
Threshold Bit Score: 144.379
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001863348          5 HHVHFDAAv--iNDELHDNTVIYQISGEGkQLTVHLGFLQIKHRYRLELNIPVNAlaeag------fdvgSNKSFIVEEK 76 
ESO01224             19 nRVHFPAE----QLDRHDSRIIVNGDADCkCLDVHLGFLQLLHDYHINFRIPDKL------------------GKDLVCD 76 
XP_001627979         21 HHVHFS------EDVTPNTDIQVKMKGKS-EADVHVGFLQLKHKYEIEFNIPKAP------------------EAKLSPP 75 
XP_002601654        275 GHVHF-------PADLHGPELRVTQTDQD-HFSVNLGFLQIHRTYQAKFTLRHGF------------------GPSLSAP 328
XP_003384682          5 SHVRFAEGthldPDKLH----VTDDGSQYhLPEAHIGFLRNHHTYHADVPIKHGL-----------------GSDVTVTV 63 
EFX74684              7 HHVKFNEEh---DNYNKQNSINIQKISQW-KFQVHLGFLKLNNTYEIIIDVGPILespqspdntawisndCSAGAYTSIK 82 
EFN84435              6 HHVHFSGG----SGLGKDNNIMIQPQRHG-QIDAHLGFLQLHHRYHIEFSVPWNTcih----------lgGETVAPAIIA 70 
WGS:AANI:GJ12323-PB  15 HHVHFDATtlktDDFGSDSCVTYQRSGD--TIVVSLGFLQINHRYLIDLNLPVSLfgn---------tgaPGTKFVPDVS 83 
ETN58989              6 HHVHFDQTv--iNDGLHDNSIIYQVAPDGrSLMVHLGFLQIKRRYRIELNVPAQLlknag------fqigANTGFVVQDN 77 
EEC11671             11 HKVHFPESl---DTFGHDSSILVQPLNDV-LINVHLGFVQVNHRYEVRFQFATPP---------------HLGSLSVRTQ 71 
XP_001863348         77 AIPNINcklltfptn----iltdrdgkQHYTVE---VEFFAHKEKLLKEHLEVCGSEDHDRKLHLTFVARVLGRGKGTPM 149
ESO01224             77 PLQNLNvqlle-----------avptdNGHELL---LSFKAQKEKLMKEELIINSATDSDAHIKLILHARVLGKGKGTPA 142
XP_001627979         76 SEAAPTlrivev---------tpsgdgKGQKIL---LELDAHKEGLLHHKFVLENHENKEK-FKVVLHARVLGSKKGRPM 142
XP_002601654        329 PLQSVYftikeihhnvdnntdtegnqqDSHTLV---LEVCTEKDGVVKEELFLTTEEDVTKKIFVELHARIMGKGKGTPL 405
XP_003384682         64 PNYNLYvrinevq--------pttaseDGEYVTpvqLEVKTIKEGRIREKVLVHSGTDDSKSMEILITAQVMEANQGNPL 135
EFX74684             83 SCENSNnk---------------------vHLH---LILKAAKPKLMNEAIKLYSSADPTVHIEIVFLARVLGKGQGTPM 138
EFN84435             71 GNQNSNchiid-----------faqdkDGLKLK---VELLAYKEKILKENIEVMCCQSGTP-LKIVLNARVLAKDKGTPL 135
WGS:AANI:GJ12323-PB  84 ATPNLHcriteft-------gtkhdehDFYEMK---IEFFAYKEKLLREVLHIVNSNNAKELLQLVIAARVLGKGKGTPM 153
ETN58989             78 PVPNLNctlvefnn-----qtvlikdeEHLAVV---VEFFAYKEKLVKEHLHLCGKEDASHTLELVLVARVLGKGKGTPM 149
EEC11671             72 DPPNLNvrvltlr--------pvdstdFKYEVV---LEMLAYKEKLLREQLVLQSSNNPMLTLTLVLNARVLGKGKGTPF 140
XP_001863348        150 LRDGIHLISVE-DNE-ESELSDWQGF 173
ESO01224            143 LRSGVHCIKVHaDDE-DSHLSDWQGF 167
XP_001627979        143 LRDGIKCMHVDkDDEdDGEHSDWKGF 168
XP_002601654        406 LKEGVRCLKVNv-EE-DSEISDWAGF 429
XP_003384682        136 LKDGVHVVSHEvEDE-----SEWPGH 156
EFX74684            139 LKDGIHLVGVEl-DE-ESEASDWQGF 162
EFN84435            136 LRNGIRSIAIEgVDQ--DEVse---- 155
WGS:AANI:GJ12323-PB 154 LRTGIHCIGVErDDD-DSESSDFAGF 178
ETN58989            150 LRNGIHCIGVDpEEQ-ESELSDWQGF 174
EEC11671            141 LKTGIHCIGVEm-EE-ESDLSDWQGF 164
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