Conserved Protein Domain Family
Laps

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pfam10169: Laps 
Learning-associated protein
This is a family of 121-amino acid secretory proteins. Laps functions in the regulation of neuronal cell adhesion and/or movement and synapse attachment. Laps binds to the ApC/EBP (Aplysia CCAAT/enhancer binding protein) promoter and activates the transcription of ApC/EBP mRNA.
Statistics
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PSSM-Id: 462976
Aligned: 31 rows
Threshold Bit Score: 68.1711
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q7PNZ0         1 MTARCKKRRnQNNAIRRAKNKVKEVKKLKKMLGFieeDVGEGNLMDKLKDITEQKKKEEELELLKKETLAeivqKEqka- 79  Anopheles gambi...
EFN75199       3 KSLRSKWKR-KCRAVKRERYAAKELDRLKKTLGId-dKAPKDVEMANLEEIATVVDAKQVRKDIEVKQs-----AT---- 71 
XP_011267025   3 KSLRSKWRR-KCRAVKRERYAVKELDRLKKTLGIe--NAPKDVEMADIQEIATVVDAKKIKEEQA--KAKdtksDA---- 73 
XP_011051019   3 KSLRSKWKR-KCRAIKRERYAVKELDRLKKTLGId-dNVSKDIEMTEITEIATVVDAKKVKEDVKAKRVEdvksKT---- 76 
XP_012063967   3 KSLRSKWKR-KCRAIKRERYAVKELDRLKKTLGIdddNVSKDIEMTEITEIATVVDAKKIKEDVKAKQVKdaksTT---- 77 
Q9VZC8         3 RNNRSRKRRdEMNKIKKARYEAKELIRLKKTLGLldaDGNE--IMKDISDVVEIKTAKELKREAKSKEEQeliyEHqe-- 78  fruit fly
EDV95624       3 RSNRSRKRRdEMNKIKKDRYDAKELIRLKKTLGLldaDGKE--IKMEIGEVAEIKSAKDIKKAAKTREHQeliyEHqe-- 78 
EDS41626       1 MTARSKSRRdKNNRIRRAKNKVKELKKLKKTLGMideDGMD--IMEKVKEITEQQKKKEEEEKIKAEVREdivkEEtkd- 77 
Q17PN1         1 MTARSKSRRdKNNRIRRAKNKVKELKKLKKTLGLideDGMD--IMEKVKDITEQQKKKEEEEKIKQEAMEeiirKEtnel 78  yellow fever mo...
ETN59585       1 MTARSKKRRnKNNAIRRAKNKGKELKKLKKTLGLideDGME--LMDKIKDITEQDKKEEELEIVKKEAMEdivkREtke- 77 
Q7PNZ0        80 taKREKFITVVnpkTNvKHlyNVKTKRDQFGQYPAWYNPRKERKKQMVREGKDaRRKE 137 Anopheles gambiae str. PEST
EFN75199      72 --TTDGNYMEV---EN-VRvyNKKTLRDQYGNYPVWMNLRKINKHKKGRAKTQkANTK 123
XP_011267025  74 --ITDQEQMEVekiEN-ARvyNKKTLRDQYGNYPVWMNRRKVLKHKKGRAKMQkASKV 128
XP_011051019  77 --VTGEEQMEV---EG-ARiyNKKTLRDQYGNYPVWMNHRKIVKHKKGRARTKkTDKi 128
XP_012063967  78 --VIGEEQMEI---ES-TRiyNKKTLRDQYGNYPVWMNHRKIIKHKKGRARTKkTSKT 129
Q9VZC8        79 slEKGEKVKVTnenTGvEHifNSKTLKDQYGNYPAWFKKKKTAKRLRKKQHSQkKNFK 136 fruit fly
EDV95624      79 slEKGKEIFQVnekTGvEHvyNSKTLKDQFGNYPAWFKKKKTAKRLRKKQHAQkKNFK 136
EDS41626      78 tvDHNEYIEIVhpeSKvKHrhNTRTKQDQFGQYPVWYNARKEKRKQLLRDGKIkKKRG 135
Q17PN1        79 glETEEYVEVEhqeSKvKHkyNAKTKRDQFGQYPVWYNARKERRKQLLIEGKIkKKRG 136 yellow fever mosquito
ETN59585      78 tvDPNKYVEIVnpkTNvKHvyNEKTKRDQFGTYPVWYNAKKEQRKQKMREGKItRKRQ 135
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