Conserved Protein Domain Family
Otopetrin

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pfam03189: Otopetrin 
Otopetrin
Statistics
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PSSM-Id: 460840
Aligned: 45 rows
Threshold Bit Score: 198.256
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9W4A6       203 FLRVGAIAFGLGAMIYIGLEFG---SFFEI----PFDSPCHH-------------ILIGVNPLLQMIFTFMQMYFIFMNA 262 fruit fly
CDS36423     319 YLRLGTVVFGFGVMIMDGFRVA---DQFRAv---NSERTCHS-------------ILWIPLNVIHAIYIFWQTYFLFKYH 379
ESN90352     137 FV-AGLVLFYTLSFVMDFVHLM-------------AKVDCSPvwmackynvkvtfIVDVIFHITRIVFFGCSTFFAIVYR 202
EFA02328     335 YLKIGAAVFCLGHLIHSGLLIGy--QILFLtsdgEDFYKCAT-------------VTSLILDIVYPIYSFFLLYFIFKYS 399
4_pfamImport   1 YMKVGAAGFCLGHLIHSGLLISyqlAFLMTd--sANFLRCAS-------------IATLVLDLLYPTYSFLQLFFIFKYS 65 
Q22977       146 YLRLGTVLFGTLGSVLWGCEIF---LCFFT--------ETRH-------------NIYVVKYILAFLFTYLQMHFLCCNS 201 Caenorhabditis ...
XP_003110541 162 YLRLGALLFGTLGSVLWGCEIY---LCFAG--------ECVH-------------RLVVSKHIAAIIFTFLQMHFIVCNS 217
Q22976       160 YLRLGAIFFGTLGSVLWGCEIF---LCFSG--------ECVH-------------RLVVAKHIAAIIFTFLQMHFIVCNS 215 Caenorhabditis ...
PDM84064     193 YLRIGCVVFGLIGVVYYVLMAL---VCTFGw--dGITANECN-------------ASGIAISVMAALFVFSQMWFVYCNG 254
XP_002634537 177 FLRLGSVVFGVTGVVYYAFLVF---LCELD--------TNCS-------------ALSTSLDVCAIFFIFIQMHFIFCNW 232
Q9W4A6       263 RLNIHR-FKVIARFGLMHVVATNICVWIRTLVKE-----SLLEitiyhqknePEAGASSIAHSIRQHALRHagtvlrtha 336 fruit fly
CDS36423     380 RVTFNV-QKFIIRFILSHMAVVNLGQWLSTVVEEvvsseEKSE---------HLTNTMRSLADAVVAKQSL--------- 440
ESN90352     203 SFIFAS--KCWVRYSLAVLFGVNLALWFDVLLHE------------------SARIINNSSSSAIIDNE----------- 251
EFA02328     400 NIIVNR-HLAVVRFGLMHCIASSLCFWVWTILRE-----TIESlshhkedsaSEELPTTSESAFFSSPQalp-------- 465
4_pfamImport  66 NVIINR-FKVAGRFALMHCIGSNLCFWIWTILREtvdslYHGE---------DAPVSLHHLNSHKAMYMTGmflavf--- 132
Q22977       202 KIDLPK-NNFLASFGMMHCVAVNLWVWFSLCLAKavyksDKKT---------LKLQKAEEKYKKKNMTITEa-------- 263 Caenorhabditis ...
XP_003110541 218 KITFHR-SNHLASFGMMHCVAVNIWTWFSMCLVKaqvkrLKKQ---------KKEMEYHKNSTDSYSSSSSsssssseee 287
Q22976       216 KITFHR-SNILASFGMMHCVAVNLWTWFSMCLVKaqvkkLKKQ---------KKELEYHSSSSSSSDSSSSseeilepe- 284 Caenorhabditis ...
PDM84064     255 KIAINGnSRYYISLGLMHLVATNLWLWIRYILYE--------EaqtlkeirlAKFDHNSTSTSDILQDLlav-------- 318
XP_002634537 233 KLSITG-SHMVARIGTMHLVAANLWTWIRYVLMEegvmeKEIR---------EVFKHRPMMGHYRNLSFDSsess----- 297
Q9W4A6       337 gpnsefevldgedilpkdvyksdnvlsklvrntvdgiskslgmggdqaldssttssstttttrapfttpnyqwhsttmar 416 fruit fly
CDS36423         --------------------------------------------------------------------------------    
ESN90352         --------------------------------------------------------------------------------    
EFA02328         --------------------------------------------------------------------------------    
4_pfamImport     --------------------------------------------------------------------------------    
Q22977           --------------------------------------------------------------------------------     Caenorhabditis ...
XP_003110541 288 del----------------------------------------------------------------------------- 290
Q22976           --------------------------------------------------------------------------------     Caenorhabditis ...
PDM84064         --------------------------------------------------------------------------------    
XP_002634537     --------------------------------------------------------------------------------    
Q9W4A6       417 klkkfitsattaattaagssstasstttisptissttipsttissttisssTTFSPFSPSTTTTTTTTAAAlnletsgse 496 fruit fly
CDS36423     441 ---------------------------------------------------TSDLGVPAHATLKETSQEPI--------- 460
ESN90352     252 ------------------------------------------------------IIIIRCLQRNDSTDMQShn------- 270
EFA02328     466 ------------------------------------------------lisYDKRGAKLLTAYLNTTVRQF--------- 488
4_pfamImport 133 ----------------------------------------------nsvydQNIFKNREIPRNSVRQTALI--------- 157
Q22977       264 --------------------------------------------------vAETITTTIASIVSSESSSGFradekq--- 290 Caenorhabditis ...
XP_003110541 291 ----------------------------------------esstvleglveAVVEKMKPMMSSYSSSTSSY--------- 321
Q22976       285 -------------------------------------------sstllenlIEVVLEKLKPGKGTTYTSTP--------- 312 Caenorhabditis ...
PDM84064     319 -------------------------------------------------dsHGGSHHDDNNSTDFIHALHT--------- 340
XP_002634537 298 -----------------------------------------------qeqsSEMFSSHEDEHDKKIVGSCQ--------- 321
Q9W4A6       497 spfgglqrilssaappslapvdgfgsasaatptsgsgagsfvdsflastlspasstegsasimnnlfgqgpmensfqtyt 576 fruit fly
CDS36423         --------------------------------------------------------------------------------    
ESN90352         --------------------------------------------------------------------------------    
EFA02328         --------------------------------------------------------------------------------    
4_pfamImport     --------------------------------------------------------------------------------    
Q22977           --------------------------------------------------------------------------------     Caenorhabditis ...
XP_003110541     --------------------------------------------------------------------------------    
Q22976           --------------------------------------------------------------------------------     Caenorhabditis ...
PDM84064         --------------------------------------------------------------------------------    
XP_002634537     --------------------------------------------------------------------------------    
Q9W4A6       577 dlgheeatglvsfenlesldniypaalssnigtlnSTAC--GRIdim-------------gtiVYDSAPYLYPFIIEYSL 641 fruit fly
CDS36423     461 -----------------------------------TAHC--HSQ-------------------AATFVHYLIPCGIEYSL 484
ESN90352     271 ----------------------------------fTIQCfgEETnif-------------kflNVSVVPLCYPFMYE-SC 302
EFA02328     489 -----------------------------------VSEC--QNDagl-------------sliYRNYSPYLYPFSVEYSI 518
4_pfamImport 158 -----------------------------------LKKC--HGPmqf-------------kivFETFSPYLYPFTIEYSI 187
Q22977       291 ---------------------------------------------------------lrslykLGSAANFLLTTMVEFSL 313 Caenorhabditis ...
XP_003110541 322 -----------------------------------------PTYsynstsnht-llrmqsmarLGDFSSFLLTCLVEYSL 359
Q22976       313 -------------------------------------------YpytnssnttsllrmqsmvrLGDFSSFLLTCLVEYSL 349 Caenorhabditis ...
PDM84064     341 -----------------------------------AHDC--KGVqc----------------lFGEFSEFMYTCVVEYSL 367
XP_002634537 322 -----------------------------------AVECf-----------------------LGSLSEIMFTSIVEYSL 343
Q9W4A6       642 IGAVVLYVMW---------------------------------------------------------------------- 651 fruit fly
CDS36423     485 IAGAIFYKMF---------------------------------------------------------------------- 494
ESN90352     303 VLLCERFMHWfchckrmsvrtsfkralkqpnqpsvdeetkveddnvtnvlgvnenneitiksdhlsepinenngsfylvd 382
EFA02328     519 LVVGVLFVIW---------------------------------------------------------------------- 528
4_pfamImport 188 LVVGVLFIMW---------------------------------------------------------------------- 197
Q22977       314 IAAAVYFIVW---------------------------------------------------------------------- 323 Caenorhabditis ...
XP_003110541 360 IGAAVCFIIW---------------------------------------------------------------------- 369
Q22976       350 IGAAICFIIW---------------------------------------------------------------------- 359 Caenorhabditis ...
PDM84064     368 ICAGVAFVFW---------------------------------------------------------------------- 377
XP_002634537 344 IAAAVMYIVW---------------------------------------------------------------------- 353
Q9W4A6       652 ---------------------------------------------------------KHIGRypgrmn---------ded 665 fruit fly
CDS36423     495 ---------------------------------------------------------QRIGH------------------ 499
ESN90352     383 ssndeceldnkefssaedeneledeevitdesdlddhsfhdisdinqeannnndtssKNINQqvyvkscihsevsrekmd 462
EFA02328     529 ---------------------------------------------------------QSIGKckqk-------------e 538
4_pfamImport 198 ---------------------------------------------------------QNIGThkhcrnddwns------- 213
Q22977       324 ---------------------------------------------------------KHEGEqtpqda------------ 334 Caenorhabditis ...
XP_003110541 370 ---------------------------------------------------------KYMGAtsieenvd---------- 382
Q22976       360 ---------------------------------------------------------KYMGAtniemkvd---------- 372 Caenorhabditis ...
PDM84064     378 ---------------------------------------------------------TNCGV------------------ 382
XP_002634537 354 ---------------------------------------------------------RNIGRqdhg-------------s 363
Q9W4A6       666 leHRLEVMLsr---------------------raVAMAQQArs-----------------grVDCVGSSKGLFFGL---L 704 fruit fly
CDS36423     500 --VQRRVPHsggas---------------dpipdNTETHVLplshi-----------rpddpTECHRAHKGLFVGL---L 548
ESN90352     463 fhSRADNSNtaeaqnsscsemfdsatrdnsqqiiVADNEEAnnesrrndgqltgkhskrrlsKNISDSDRKMVGSLgcaL 542
EFA02328     539 emSSTRQCDt-----------------------pVGNNDNLesnv--------------vihADCHSANKGLFSGI---V 578
4_pfamImport 214 ----------------------------------------------------gdlmsnvvlyADCHSSNKGLFAGL---I 238
Q22977       335 --------------------------------------------------------rkkhvrFDCKSTSVGIFAAI---V 355 Caenorhabditis ...
XP_003110541 383 -------------------------------------------------------kkkkklrMDCTSTTVGLFAGI---F 404
Q22976       373 -------------------------------------------------------kkkkklrMDCHNTTIGLFLGI---F 394 Caenorhabditis ...
PDM84064     383 --HGEGEKI-------------------------------Ddprpqrr--------krnivtIDCSRTAEGLFAGF---L 418
XP_002634537 364 tyVK-----------------------------------RKhq-----------------irVDCSKTTTGLFLGL---A 388
Q9W4A6       705 LLVGALICLILFFVLVRHQQFSLlAIYLADA-SHCI--------------LMAFAILAIIVGFIRVKNLKFrc------e 763 fruit fly
CDS36423     549 LFLATLVALALFYILQRRHSYKS-ALTLYQI-NYIV--------------LFAIGIIAVSIALYQIKVLGF--------- 603
ESN90352     543 FFLFTISTNVLFFIFSLLPg----AIQKNDLsAEVKhdvinrlflyytipFYGSIIISVIYGFTVAKDFPLrrsniintf 618
EFA02328     579 IMVLTVVSVILFLIAFNDSRYTEeAVSINSS-TSII--------------ITLLMTITVIFAYRQITKLDVsq------s 637
4_pfamImport 239 VLAGSFLSIILFFVAMADSKYLDvGLSVNSC-TELT--------------LIVLMSLTVVPLYSQITKLDVnr------k 297
Q22977       356 LLIGSFISIAMHYIYNN-SDMPRtADEVIGI-AETV--------------LFCVCLLAVFGAFIRMRKLQYrl------h 413 Caenorhabditis ...
XP_003110541 405 FMTAAFVTIGIYTMLYNKKNAAG-ADLVIGI-VNLV--------------LFCVALVAVIFGSWRMRVLQYrl------h 462
Q22976       395 FMTAAFVTIGIYTMLYNKKKTQS-ADLVIGI-VNLI--------------LFCVTLLATIFGAWRMRVLQYrl------h 452 Caenorhabditis ...
PDM84064     419 FLICTILAVSLYNAYSTDA---YmAQLIFLS-TEIF--------------FYGVAIVVCCYAFWRMKVLAFnhdqdende 480
XP_002634537 389 FLAVTFTSMVVYYGFTMMNKSKD-AAFVYAF-TDMF--------------QYVLSTIGVLTAIYQMRALKYfnkkthiqn 452
Q9W4A6       764 EQS----NLNDILLRISAFGLFTYSVFSIIAGSLKVLES--EPSLLVT---------TTGGVAVFQVILQLLFIADVSRR 828 fruit fly
CDS36423     604 RELseedAFDDNLLLLGLVAVLFYDLFLLIPAVDAKEEHk-KAGAMFV---------GKAILEMVQALLQVFLILEASRR 673
ESN90352     619 QGL-------DYLLFISASGPFAYNVFSLVAAYNK-------PSILVLygmnaigsvVVQVVNILQVYIQIPFCFFAGRV 684
EFA02328     638 HVS----LLDDLLLFGCIPAFFLNGIVSIIPAVIS-------QNATSI---------VLIILEVGQVLVQTPLIIDGLRR 697
4_pfamImport 298 AVS----LLDDLLLFICIPAFFVQTILIITPAWYA-------ENYVGL---------VTAVLQTVQVLIQTPFISDGLRR 357
Q22977       414 AHGq---VVDEILLIVGLAGEIVYCSTGLDLYLNGRLENtpGTSCLTV---------VAFVMRIVQVVVQSVFILVASRL 481 Caenorhabditis ...
XP_003110541 463 AHGe---VIDEILLIIGLVGELVYCSIGFDMIINGRRTGk-NAPNLAI---------AVFTFRIVQVIIQAMYILIASRL 529
Q22976       453 AHGe---VIDEILLIIGLVGELIYCSIGFDMIVNGNRTGs-HVPNLPI---------AVFTFRIIQVIIQAMYILIASRL 519 Caenorhabditis ...
PDM84064     481 SAE----FLDEILLVVGLLGELVFCLGGLLAFVNQNEIH--ALAVLLF---------VSNFLRLIQVTIQSGLIMIGSRL 545
XP_002634537 453 SDQe---LLDQILLSIGLVGELIYSVAGLVGLTGEKQWT--NFSFVLL---------FVHIFRLIQVGTQT-FLLHVARS 517
Q9W4A6       829 R--VHLPEHDRSKP----GRQIVTFLLICNVAMFAIYTFEAQKVFAN--PVQLEFYGFVPWSIIQRITLPLCIFHRF 897 fruit fly
CDS36423     674 E--AGEMGHTISKP----GRTIITLLLVLNLAMWIINTFGLKYAENH--EIFQLYYTDLAWKIITHLSLPLIIFFRF 742
ESN90352     685 ---SAVHPNGKKRPksmhFQAVLVHVSVSNATLWLVNSFATTYNNGSv-YYDSEFFGKDLWNIINSFILPITLFFRF 757
EFA02328     698 C--SNSKELRREKP----GRELLTFLIVCNVAMWIMQTFEVKSHGLQ--DHKNEFYGEELWTIIGHLCVPLMMFYRF 766
4_pfamImport 358 C--SNTKSLRVQKP----GRELLTFLIVLNVTMWITETFEIKSHTAMdgDPSSRYYGQFLWAVVTHLTFPLTMFYRF 428
Q22977       482 R--SLSASNISNQP----GKQIVTFLVVCNINLFIYHTFETIESNFGfpHKMSSVY-----SALLNISSPLVVFYRF 547 Caenorhabditis ele...
XP_003110541 530 R--CLSTANTQYQP----GKQTLTFLVIINISLFVYHAFEGMKSTYGfpSIMESKY-----FELLNISSPLVVFYRF 595
Q22976       520 R--CLSEVNARTQP----GKQTLTFLVLINITLFVYHTFEGMKSTYGfpALMETKY-----FELLNISSPLVVFYRF 585 Caenorhabditis ele...
PDM84064     546 VldIENPKTIRYKP----GKQVITLLLIINLALFFMNIFEAQKAGVT--DEVVQMYGGRSWALIVRGCSPLTVFYRF 616
XP_002634537 518 V--RMGCEDREAQP----GKQAITFLLTANLAIFFMNLFESEKAGVS--EIIIEYYGKRSWVFLVRSFSPLTIFYRF 586
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