Conserved Protein Domain Family
Stork_head
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pfam10264: Stork_head 
Winged helix Storkhead-box1 domain
This is the conserved N-terminal winged helix domain of Storkhead-box1 protein which is likely to be a DNA binding domain. In humans the full-length protein controls polyploidization of extravillus trophoblast and is implicated in pre-eclampsia.
Links
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Statistics
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PSSM-Id: 431182
Aligned: 15 rows
Threshold Bit Score: 121.241
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_015793117  237 MSLVCQAKFTPLTEALCKCINDFNNRSTHVFLGDIAEAIKQSYPNIIPPTADMIKKTLRSLQRAGKVrFSTSEGYFLVKP 316 
EDX11326      118 VTPTVQGQFTPLPEALCDVIMDLTAEGQSATIEHVRSKLGSRFPHMTTPATEVIYDSLAQLMQEQKI-YQTSKGYFIFTP 196 
Q7Q578        118 VTPIVQTQFTPLTEALCDVIMELTSQGQSATIENIRNRLRSRFTHMQQPSVEVIYDTLVQLMQEIKI-YQTSKGYFIVTP 196  Anopheles gam...
XP_002432938   21 vSLINQGQFTPLPEALCWVILELTSSGQHAVLESIRNCLHLSFPDIEKPSSQVVYDTLAKLMSDKKI-YQTSQGYFIITP 99  
XP_016660151  131 vEDLNQGQFTPLSEALCLVILELTSANQNATIDTVRSALKIFFSNIQPPAEHIIYDAMVNLMSDNKI-YQTSRGYFVVTP 209 
EFN75110        8 VAPVSQGQFTPLPEALCWAILELTSQRQAATLDTLRSALRNAFPAMQRPSRELVYDALAKLMQERKI-YHTSQGYFVVTP 86  
EFX83794       72 VQPISQSQFTPLPEALCWVIWELNLAERSTALDDVTAALGNAFPDLVPPSNKVVYDTLGKLIRDRKI-FYNGKGYGVVTP 150 
XP_019473054    1 MNPCSLSQSIPLAEGICCAISDMNAHQRMVTQKTLVEQLVKRYPGIAVPSQKILYNILGTLIKERKI-YHTGEGYFIVTP 79  
XP_003258247   59 MNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLEHLMKHYPGIAIPSEDILYTTLGTLIKERKI-YHTGEGYFIVTP 137 
EDL32080        1 MSPIAQCRFVPLAEVLCCAIADMNAAQVMVTQQSLLEHLIKHYPGIAVPSPDILYSTLGALIQERKI-YHTGEGYFIVTP 79
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