Conserved Protein Domain Family
Spatacsin_C

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pfam14649: Spatacsin_C 
Spatacsin C-terminus
This family includes the C-terminus of spatacsin.
Statistics
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PSSM-Id: 464236
Aligned: 33 rows
Threshold Bit Score: 287.962
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ETN66185     1663 ALGNALLRYCDALrlyrkre-rqeggsASANVQDALEsldtlivqteasdaggndsdllerldtilqqqvlslkkqntII 1741
XP_001748245 2055 DVGHALLRLNAS----------------KENGLETSV-----------------------------------------SQ 2077
EFC49385     2684 SIARQLIKLIDSDde-----------tNDDSPHKKKSrgil----------------------------------nlkCK 2718
Q55GD2       3385 TFGMKLIEATRINyesyfsvdnspgifGNTGMGSYVSpslkqqsntlngtggggg-----ngggnngsgklsspigmeAE 3459 Dictyostelium...
EFA86524     2824 TFGMRLLEATGIDfdkaavtsspvfakANSLSPSGME-----------------------------------------AE 2862
XP_004361431 2479 TFGMKLLESLDIDvekyqstnspiisgENSSSSSSSSd---------------------------------------aIS 2519
XP_002969877 1021 ELGHALMRLVIS---------------GHDMPHA--------------------------------------------CE 1041
ERN03875     3302 EIGHALMRLVIT---------------GHDIPHA--------------------------------------------CE 3322
XP_009409341 2871 halMRLVMTGQE------------------IPHA--------------------------------------------CE 2888
EAX91368     1710 SVGDHLFQRAKEL-----------------QGSQPIS-----------------------------------------VI 1731
ETN66185     1742 VALLVKAHDCFVHECSMEGIMEVLACCKQLT-QALTAAKSWNLIVRLLVGIGRYRDMCYCFETLIKNEQFESLLGQfDDR 1820
XP_001748245 2078 VILMSAAYACFKLGCDMRGLQRVHFHVQNNLvPRLEAEGDYRNMMKLVMGLKTYRRLEYVFDHLYKHHQLEVMLGSsTRD 2157
EFC49385     2719 VEIIIRAYHCYHMSSSFEGIESILKRIKGPIiQEILDDHDFSLIVRLLVSIPDFSELTFLFDILIENEQFELILKK-NKN 2797
Q55GD2       3460 VEMFVRAHFCFVIACSVDGTILVLNMVKSRV-NYYADAGKYKLLVRLITGMQCYNELQSIFDILLQHNQFELLLRK-KIH 3537 Dictyostelium...
EFA86524     2863 VELFVRAHFCFVVACSVDGSILVQNIVKSRI-NYYADAGQFKLLVRLITGMQCYNELQGILDILLQHDSFELLLRK-KIH 2940
XP_004361431 2520 VEIFIRAHFCFVIGCSVDGTIMVLNIVKSRI-QYYASKGEYKLLVRLVTGMQSYNELQGILDILLQHDQFELLLRK-KIH 2597
XP_002969877 1042 VELLILAHQFYESSACLDGMDVLVALAATRV-EAYVAEGDFSALARLVTGVSNFQALRFVLDLLIENGQLELLLKKrAAV 1120
ERN03875     3323 VELLILSHHFYKSSACLDGVDVLVALAATRV-ESYVAEGDFSCLARLVTGVSNFHALHFILDILIENGQLELLLQKfSVA 3401
XP_009409341 2889 VELLILSHHFYKSSACLDGVDVLVTLAANRV-ESYVLEGDFSCLARLVTGVSNFHALNFILNILIENGQLVLLLQKySTA 2967
EAX91368     1732 VNLLLHSSMC---TSDIDECAEMLDHIL----DKLVEEKQLSLIINIVTIFKDPALLPRYFQHLIAQEKLDALPHS-TLS 1803
ETN66185     1821 A----AS----GrrLQTAIIAYLNEHCPERKDYFRLAALHFRMYKEIAELWEAEARATIEAIVATYgqrrlv--srketv 1890
XP_001748245 2158 LsateQA----E--YKTALVDFFQRRYPEDTDAFEMLALRFSLDYEIGQSRLKNARRIAQKPNLKF-------------- 2217
EFC49385     2798 TdhdnNN----Q--LKMALSSYVQTKFPEQNEKLAMVYLRFNMLKEYGTYLYNRGCKGIKVIHKRLtdkddsstsvssnq 2871
Q55GD2       3538 Qhe-dQN----G--LKLALHSYLMKKQPLYQDKLEMLFLRFNMYREIALNNEQKARSRLESLGKMVdnhygg--sgiggn 3608 Dictyostelium...
EFA86524     2941 Qhe-dHN----G--LKLALHSYLLKKQPLYQDKLEMLFYRFNMYREIAALHEHRAKQKLESIVKDP-------------- 2999
XP_004361431 2598 Qhe-dHN----G--LKLALHSYLLKKQPLYQEKLEMLFLRFKMYREIAASHEHKAKQLLESLNIPPsk----------el 2660
XP_002969877 1121 DalkeSSasvrG--FRMAVISALKHFNPHDLDAFGMVFSHFSMAHEMANLLESRGRKGLTR------------------- 1179
ERN03875     3402 DsttgAAeavrG--FRMAVLSSLKHFNPHDLDAFAMVYNHFDMKYETSSLLESRARRSLQQ------------------- 3460
XP_009409341 2968 EmatgTAaavrG--FRMAVLTSLKLFNPHDLDAFAMVYNHFDMKHETASLLESRSLQYMQQ------------------- 3026
EAX91368     1804 K----------K--VGRVIMNCARHVQPFEPQKYFDLTLNYMLYRDHAELRMECGLRLLR-------------------- 1851
ETN66185     1891 CqqRLQTTAMLLTELTSAMDAYTHATDNYLLDNNLTLAQRAASNAELVALQIFFVRQSlgtekggggasmsspasstnps 1970
XP_001748245 2218 ------------DDLELSIQMLREAAVKFDKAACPQLVRECLLLARIVGLQAQLQ------------------------- 2260
EFC49385     2872 SitHLDEHVPLEHVMKIVCENFESAASSLAKEDCCQTAVKSTNLAALVKLQLKFYNELpnkkk----------------- 2934
Q55GD2       3609 KsnSSLNSNSSKQELLSIMKDFLDAADNYSKERSQRTAQTCISMGALIALQIKSPE------------------------ 3664 Dictyostelium...
EFA86524     3000 -----KQPGNYIKDLLIVMESFLNAADNYAKERSNRTSQYCVAMGTLVALQIKLPD------------------------ 3050
XP_004361431 2661 SkpSSPIAQQYIKDLLNIMREFMDASDNYAKERSNKTSQVCVSMGILVAAQIKNLD------------------------ 2716
XP_002969877 1180 ---SIRNDPEQNEEVLEIMRFFVEASEVYAGIDCGNKTRWCCAQASLLSLQLRMPE------------------------ 1232
ERN03875     3461 W--FLQHDRERSEELLDSMRFYVEAAESYSTIDAGNKTRQACAQASLTALQIRMPD------------------------ 3514
XP_009409341 3027 Wl-SCRDKDLRTEYLLDAMCHYIEAAEVLSGIDAGQKTHNACAQASLLSLQIRIPD------------------------ 3081
EAX91368     1852 -------GSPDKNKLQEASSHFLLALAYFLHEKCYSLSMECLKKLSLISLQLEVPD------------------------ 1900
ETN66185     1971 psrastaggsstgssasqepsntcLSVLNIRSNDegtsgggvassgaLLYYINFLLTVPQALIVGRAYGV--EINWPFAI 2048
XP_001748245 2261 ------------------------PNVLDLSRSE-------------LEQFLVSHGAYPEASIVAQYYGAdnPTVWLRPV 2303
EFC49385     2935 --------------------lqnlPIIVELGLKE-------------ARTFIQNHADFEESLIIANAYDIntMSDWIEPI 2981
Q55GD2       3665 ------------------------IPIINLRQNQ-------------AKHSMTIRPFFKESLIIANAYNLnaYSEWIDVL 3707 Dictyostelium...
EFA86524     3051 ------------------------IKLINLKQSE-------------ARQTMISRQTFRESLIIANAYNLniYSDWINVL 3093
XP_004361431 2717 ------------------------IRILNLKQSD-------------ARLLMQSRGNFRDGLIIANAYNLnnYTEWLNVI 2759
XP_002969877 1233 ------------------------IMWLNLTETN-------------ARRLLVDQRRFQEALIVAEAYGLnqPAEWVPVL 1275
ERN03875     3515 ------------------------HMWLNLSETN-------------ARRALVEQARFPEALAVAEAYGLnqPSEWVLVI 3557
XP_009409341 3082 ------------------------INWIALPETK-------------ARRVLVEQSRFQEALIVAEAYKLnqPSEWAPVL 3124
EAX91368     1901 ------------------------MNVLHLDESQ-------------VLHLMKTK-DFPFALTTAVAYDMdtEVNWAEAI 1942
ETN66185     2049 YQHYVIDGQRG-YLEDYLNRLPLTDAIIETLVKMFQL 2084
XP_001748245 2304 FHQVVELGNVD-YWTDCAQGNMFEASFYRSVVDLYLK 2339
EFC49385     2982 YNNCVKKGDLE-YFNSLRQYLPTSTNLFREVAKRVKL 3017
Q55GD2       3708 FYQVLANGNFN-YLNDYISYFSHSNLFYSDLIKRYKA 3743 Dictyostelium discoideum
EFA86524     3094 FQQVLCLGNFT-YLQDYIANFSVPQNLFHDLIKRFKG 3129
XP_004361431 2760 FNQFLVLANFN-YLSDYLNNFSSNINLYHDLIKKYKS 2795
XP_002969877 1276 WNQVLSPGWIEhFLTEFVASLPLRPSMLMELARIYRS 1312
ERN03875     3558 WNQMLRPDIIEaFLDEFVAALPLLASMLLELARFYRS 3594
XP_009409341 3125 WNQMLKPDLIEqFVAEFVAVLPLQPTMLLELARYYRS 3161
EAX91368     1943 FTQSVQNKGEE-FLTAFQYFRPLTSNLCSQVVKMYKE 1978
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