Conserved Protein Domain Family
tfb4
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TIGR00627: tfb4 
transcription factor tfb4
All proteins in this family are part of the TFIIH complex which is involved in the initiation of transcription and nucleotide excision repair.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Links
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Statistics
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PSSM-Id: 273181
Aligned: 4 rows
Threshold Bit Score: 417.312
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
CAA95001  22 SPSLLTVIIEIAPKLWttFDEEGneKGSIIKVLEALIVFLNAHLAFNSANKVAVIAA-YSQGIKYLYPEsts--alkASE 98  baker's yeast
BAA21460  22 TPSLLVVILDANPASW--YSLSK--KVPVSKVLADITVFLNAHLAFHHDNRVAVLAS-HSDKVEYLYPS--------IAP 88  fission yeast
CAA03035   7 ELNLLVIVVDANPIWWgkQALKEs-QFTLSKCIDAVMVLGNSHLFMNRSNKLAVIAS-HIQESRFLYPGkngrlgdfFGD 84  unidentified
CAA87423  49 NMSTLSVLIETSSCSWgmLASAHg-DRTIGIILRAIVSFCNAHLGQSANNQLLVFAYgRNVDNKMIYSSt-------RCE 120 Caenorhabditis elegans

CAA95001  99 SENKTRSDLKIINSdMYRRFRNVDETLVEEIYKLFELEKKQIEqnsqRSTLAGAMSAGLTYVNri-sKESVTTSLKSRLL 177 baker's yeast
BAA21460  89 EQKVAEVDPTKEAN-TYRKFREVDDLVLSGMKRLMSSTDKVSR----KTMISGALSRALAYIN----QVQNKNTLRSRIL 159 fission yeast
CAA03035  85 PGNPPEFNPLGSKDgKYELLTSANEVIVEEIKDLMTKSDIKGQh--tETLLAGSLAKALCYIHrmnkEVKDNQEMKSRIL 162 unidentified
CAA87423 121 DRNASFLVVKRLRElLSSDALTNDATIGAPLGPALAHAFCHMKkd-sRVVTADPCDDSLGPQTtseqSETASEKATNRAV 199 Caenorhabditis elegans

CAA95001 178 VLTCgsgsSKDEIFQYIPIMNCIFSATKMKCPIDVVKIGGSkeSTFLQQTTDATNGVYLHVESTEGLIQYLATAMFIDPS 257 baker's yeast
BAA21460 160 IFSL----TGDVALQYIPTMNCIFCAQKKNIPINVCNIEGG--TLFLEQAADATGGIYLKVDNPKGLLQYLMMSLFPDQN 233 fission yeast
CAA03035 163 VIKA----AEDSALQYMNFMNVIFAAQKQNILIDACVLDSD--SGLLQQACDITGGLYLKVPQMPSLLEYLLWVFLPDQD 236 unidentified
CAA87423 200 VISI----TPIMGSEHGSLMNLFFSAAKQSICVDVVSMGDDftGGILQQAADITGGSFLHAKKPQTLLKILMTNMLTDPT 275 Caenorhabditis elegans

CAA95001 258 LRPIIVKPNHGSVDFRTSCYLTGRVVAVGFICSVCLCVLSIIPPgnKCPACDSQF 312 baker's yeast
BAA21460 234 LRKHLNTPNQANVDFRATCFCHKKVLDIGFVCSVCLSIFCEPRV--HCSTCHTKF 286 fission yeast
CAA03035 237 QRSQLILPPPVHVDYRAACFCHRNLIEIGYVCSVCLSIFCNFSP--ICTTCETAF 289 unidentified
CAA87423 276 HRAVFSKLSHNSVDYRASCACHHQLVSSGWVCSICLSVLCQYTP--ICKVCKAAF 328 Caenorhabditis elegans
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